Workflow
渐冻症药物
icon
Search documents
万邦德(002082) - 002082万邦德投资者活动记录表20250918
2025-09-18 13:26
Group 1: Company Overview - The company introduced its innovative drug pipeline, focusing on Alzheimer's disease and related research [1] - The Alzheimer's II/III clinical trial is the largest key registration study in China, designed scientifically with dual endpoints (ADAS-Cog and ADCS-ADL) to evaluate cognitive function and daily living abilities [2] Group 2: Alzheimer's Disease Research - The clinical trial employs a multi-center, randomized, double-blind design with placebo and positive drug controls, assessing the drug's impact on disease progression and biomarkers [2] - The drug Huperzine A is a cholinesterase inhibitor showing potential benefits in anti-inflammation, cholinergic regulation, neuroprotection, mitochondrial protection, and antioxidant stress [2] - The controlled-release formulation of Huperzine A aims for rapid onset, reduced adverse reactions, and improved patient compliance with once-daily dosing [2] Group 3: ALS (Amyotrophic Lateral Sclerosis) Development - The company is developing WP205 for ALS, which has received orphan drug designation from the FDA and is patent pending [3] - The company plans to explore the multi-target mechanism of Huperzine A in ALS treatment and has patented core compounds for drug development targeting MCR [3]