Core Points - The theme for World Rabies Day 2023 is "Together We Act, Building a Rabies Prevention Line" [1] - Rabies is a zoonotic disease caused by the rabies virus, primarily transmitted through bites or scratches from infected animals like dogs and cats [1] - The mortality rate of rabies approaches 100% once clinical symptoms such as hydrophobia and difficulty swallowing appear [1] Group 1 - The increase in pet ownership, improved ecological conditions, and more frequent contact with wildlife heighten the importance of rabies prevention [1] - During the upcoming National Day holiday, individuals are advised to maintain distance from dogs, cats, and wild animals to avoid rabies infection [1] Group 2 - The recommended emergency response for animal bites includes three steps: washing the wound with plenty of water for about 15 minutes, bandaging the wound, and seeking medical attention promptly [2][3] - Rabies vaccination is the most crucial method for controlling and preventing rabies, with two vaccination schedules: the "5-dose" and "4-dose" regimens [3] - The "5-dose" regimen involves vaccinations on the day of exposure and on days 3, 7, 14, and 28, while the "4-dose" regimen consists of two doses on the day of exposure and one dose on days 7 and 21 [3]

Core Points - The event aimed to enhance awareness of rabies prevention among students and staff at Shandong Normal University Second Affiliated Middle School, coinciding with World Rabies Day in 2025 [1] - The event included detailed explanations about rabies, its transmission, prevention methods, and how to handle animal bites, making the information accessible and practical for the audience [1] - The increasing number of pet owners and stray animals in communities poses a challenge for schools and families in ensuring safety against rabies and other zoonotic diseases [5] Group 1 - The event was organized in collaboration with the Shandong Provincial Animal Health Technology Center to promote rabies prevention knowledge [1] - Students actively participated in the event, asking various questions about rabies transmission and pet vaccination [3] - The school emphasized the importance of proper understanding and awareness of rabies to avoid panic and enhance scientific prevention capabilities [5]

Core Insights - In 2024, China reported 170 cases of rabies, a decline of over 95% from the historical peak, indicating significant progress in disease prevention [4] - Despite the decrease in rabies cases, the number of rabies vaccinations administered has increased sharply, highlighting a disparity between disease incidence and vaccination practices [5][6] - The high fatality rate of rabies, nearly 100%, and the lack of effective treatment drive the public's awareness and demand for vaccinations [6][9] Vaccination Statistics - China consumes over 80% of the global human rabies vaccine supply, with more than 50 million doses issued annually and over 10 million people vaccinated each year [2] - The market for rabies vaccines in China grew from 3 billion yuan in 2016 to 5.3 billion yuan in 2021, with projections to reach 10.1 billion yuan by 2026 [2] Vaccination Challenges - The vaccination process is complex, requiring 4 to 5 doses within a month, leading to high costs that can exceed 1,000 yuan for a complete course [13][15] - A study covering 2 million patients revealed that only 87% sought treatment within 24 hours after exposure, and only 72% received proper care, indicating gaps in vaccination adherence [10] Market Dynamics - The rabies vaccine market in China is becoming increasingly competitive, with 23 types of human rabies vaccines available and 19 more in clinical development [18] - Leading company Chengda Biologics has seen its market share decline from over 70% to less than 40% by 2024, as new entrants capture market share [20] Pricing Trends - The price of rabies vaccines has increased significantly, with newer generation vaccines costing over 300 yuan per dose, leading to a total cost of approximately 1,500 yuan for a complete vaccination course [15] - Recently, Hualan Vaccine reduced the price of its freeze-dried rabies vaccine to 127 yuan in Wuhan, marking a 38% decrease [22] Animal Vaccination Insights - The vaccination rates for pets remain low, with only 33.5% of dogs and 35.9% of cats receiving preventive care, indicating a need for improved vaccination strategies [33] - The current focus on human rabies vaccinations may lead to a neglect of animal vaccination, particularly among stray and free-roaming dogs, which are critical in the rabies transmission chain [36]