Core Insights - The research team from Xinjiang Uygur Autonomous Region People's Hospital and Tsinghua University published a groundbreaking study on predicting biological age using large language models, marking a significant advancement in health technology [1][3]. Group 1: Research and Development - The Tianshan Yuekang model was developed based on the research findings, providing personalized health recommendations and enhancing health management [3]. - This study is the first in the world to apply large language models for multi-organ aging assessment, enabling precise modeling and intelligent alerts for aging states [3][4]. - The research integrated health databases from China, the UK, and the US, with a total sample size exceeding 10 million, making it one of the largest studies of its kind globally [3]. Group 2: Technological and Methodological Innovations - The research achieved three major breakthroughs: 1. The biological age predicted by the large language model significantly outperformed traditional indicators like telomere length and epigenetic clocks in predicting mortality and disease risk [4]. 2. It was the first to model biological age at the individual level for multiple organs, revealing the phenomenon of "asynchronous aging" where different organs age at different rates [4]. 3. The identification of 316 potential blood protein biomarkers associated with accelerated aging, with about 60% (approximately 190) being reported for the first time [4]. Group 3: Practical Applications and Benefits - The core advantages of this research include low cost, ease of promotion, and strong universality, requiring only routine health check data to create an individual's "aging profile" and predict biological aging and future health risks [4]. - This model aims to bring advanced health assessment technologies to grassroots levels, benefiting a wider population and aiding in early disease screening and proactive intervention [4]. Group 4: Global Impact and Collaboration - This "China original" technological breakthrough offers an innovative paradigm for global health management, contributing "Xinjiang wisdom" to address aging challenges worldwide [5]. - The successful experience from this research can benefit countries involved in the Belt and Road Initiative, sharing the dividends of technological progress [5].