Core Viewpoint - The article highlights the alarming increase in diabetes prevalence in China, emphasizing the urgent need for effective prevention and control strategies to address this public health crisis [9][15][16]. Summary by Sections Diabetes Prevalence and Trends - As of 2023, the total number of diabetes patients in China has reached 233 million, with a prevalence rate of 15.88%, marking a 163% increase from 88.48 million patients in 2005 [9][15]. - The age-standardized prevalence rate (ASR) has risen from 7.53% in 2005 to 13.67% in 2023, with an annual growth rate of 3.36% [9][10]. - The years of life lost due to disability (YLDs) related to diabetes reached 32.49 million in 2023, reflecting a significant decline in overall health quality [9]. Regional Distribution and Characteristics - The eastern region has the highest number of diabetes patients at 78.47 million, followed by central and northern regions [11]. - The northern region has the highest ASR at 17.20%, with major cities like Beijing and Tianjin exceeding a 20% prevalence rate [12]. - The southwestern region shows the fastest growth in diabetes prevalence, increasing from 5.65% in 2005 to 11.77% in 2023, driven by dietary changes [12]. Future Projections and Challenges - Projections indicate that if current trends continue, the ASR could reach 16.15% by 2030, 21.52% by 2040, and potentially 29.10% by 2050, adding nearly 150 million new diabetes patients [13][15]. - The healthcare system will face unprecedented pressure due to the high costs associated with diabetes treatment and management [10][15]. Prevention and Control Strategies - The article advocates for a shift from treatment to early screening, lifestyle interventions, and strengthening primary healthcare [10][15]. - A differentiated regional strategy is necessary, focusing on complication management in high-prevalence areas and lifestyle interventions in rapidly growing regions [14][16]. - Implementing obesity intervention strategies could significantly reduce the projected diabetes prevalence by 2050, potentially keeping it below 15% [13][15].

Core Insights - Personalized health check-ups play a crucial role in early screening and health management of chronic diseases [1] - Early detection of chronic disease risk factors is essential, as many potential health risks may be overlooked until patients exhibit clinical symptoms in advanced stages [1] - The concept of "precision stratification" in personalized health check-ups helps avoid both under-checking and over-checking, ensuring tailored health assessments [1] Group 1 - The importance of personalized health check-ups in identifying potential health risks and enhancing disease prevention effectiveness is emphasized [1] - The use of AI-driven questionnaires and big data integration to create health profiles for risk stratification is highlighted [1] - The "1+X" package model is introduced, where "1" represents essential checks for everyone, and "X" includes additional tests based on risk levels [1] Group 2 - Obesity is identified as a significant risk factor for metabolic diseases, increasing the likelihood of diabetes, hypertension, cardiovascular diseases, and tumors [2] - Various obesity-related metrics, such as waist circumference, body composition, and other health indicators, should be monitored during health check-ups [2] - A comprehensive approach to obesity intervention is recommended, focusing on lifestyle changes and personalized health management based on individual assessments [2]