以下文章来源于内分泌早知道 ，作者关注内分泌的 内分泌早知道 . 深度分享内分泌用药经验、病例剖析、指南专业解读并紧跟国内外内分泌领域前沿进展。 最新一项覆盖中国近6万名2型糖尿病患者的全国性研究揭示，睡眠时间与体重管理存在显著相关性。研究发现，无论是夜间睡眠不 足7小时还是超过8小时，亦或是午睡时长超过1.5小时，都会显著增加肥胖风险，这种影响甚至可能达到翻倍的程度。这种关联性在不 同遗传背景的人群中表现出明显差异，提示基因因素在睡眠与肥胖的复杂关系中扮演着重要角色。 数据表明，糖尿病患者群体中普遍存在睡眠障碍问题，而异常的睡眠模式又会反过来加剧代谢紊乱，形成恶性循环。专家特别强调，相 较于普通人群，2型糖尿病患者对睡眠时长的变化更为敏感，其体重管理更容易受到睡眠质量的影响。这项研究为糖尿病患者的体重管 理提供了新的干预思路，提示临床医生在制定治疗方案时应将睡眠评估纳入常规管理范畴。对于广大糖尿病患者而言，保持7- 8小时的 夜间睡眠和不超过1小时的午睡，可能是控制体重的关键因素之一。 ▍糖胖危机：全球代谢病双重威胁 世界卫生组织最新统计数据显示，全球超重人口已突破19亿，其中肥胖人群高达6.5亿，而糖尿病 ...

Core Insights - Personalized health check-ups play a crucial role in early screening and health management of chronic diseases [1] - Early detection of chronic disease risk factors is essential, as many potential health risks may be overlooked until patients exhibit clinical symptoms in advanced stages [1] - The concept of "precision stratification" in personalized health check-ups helps avoid both under-checking and over-checking, ensuring tailored health assessments [1] Group 1 - The importance of personalized health check-ups in identifying potential health risks and enhancing disease prevention effectiveness is emphasized [1] - The use of AI-driven questionnaires and big data integration to create health profiles for risk stratification is highlighted [1] - The "1+X" package model is introduced, where "1" represents essential checks for everyone, and "X" includes additional tests based on risk levels [1] Group 2 - Obesity is identified as a significant risk factor for metabolic diseases, increasing the likelihood of diabetes, hypertension, cardiovascular diseases, and tumors [2] - Various obesity-related metrics, such as waist circumference, body composition, and other health indicators, should be monitored during health check-ups [2] - A comprehensive approach to obesity intervention is recommended, focusing on lifestyle changes and personalized health management based on individual assessments [2]