Core Viewpoint - The stock of ZhiJie AnKang-B (02617) has surged nearly 88%, reaching a high of 204.6 HKD, representing an increase of over 1455% from its IPO price of 13.15 HKD, driven by its inclusion in the Hong Kong Stock Connect list and positive developments regarding its core product, Tiengertinib [1][1][1] Company Developments - ZhiJie AnKang's Tiengertinib is the world's first and only FGFR inhibitor to enter the registration clinical stage for treating patients with recurrent or refractory cholangiocarcinoma [1][1] - The company has received multiple positive updates for Tiengertinib, including the approval for a Phase II clinical trial in China for treating HR+ and HER2- recurrent or metastatic breast cancer, which was granted clinical implied permission on September 10 [1][1] - Tiengertinib is also involved in an open-label, multicenter Phase II clinical study for advanced hepatocellular carcinoma (HCC) in combination with other therapies, with the first patient recently dosed [1][1] - The drug has received Fast Track designation from the FDA for the treatment of metastatic castration-resistant prostate cancer [1][1]

Group 1 - The stock of Yaojie Ankang-B (02617) rose over 10%, reaching a new high of 30.7 HKD, which is an increase of over 130% from the IPO price of 13.15 HKD [1] - As of the report, the stock was up 8.83% at 30.2 HKD, with a trading volume of 24.18 million HKD and a market capitalization that briefly exceeded 12 billion HKD [1] - Yaojie Ankang announced that its self-developed multi-target kinase inhibitor, TT-00420, received Fast Track designation from the FDA for the treatment of metastatic castration-resistant prostate cancer [1] Group 2 - According to Frost & Sullivan, the global CCA drug market is expected to reach 2 billion USD by 2024, with a compound annual growth rate (CAGR) of 16.2% from 2019 to 2024 [2] - The market is projected to grow to 3.2 billion USD by 2027, with a CAGR of 17.1% from 2024 to 2027, and further increase to 4.6 billion USD by 2030, with a CAGR of 12.8% from 2027 to 2030 [2] - The company is a leader in the niche industry, with Tinengotinib being the first and only FGFR inhibitor entering the registration clinical stage for treating recurrent or refractory cholangiocarcinoma patients [2]