Good morning one and all. I'm here to talk about my needs makeover. Let me begin with my own story.13 years of my career teaching anatomy in a medical college. No growth, no promotion, no appreciation. I felt completely stuck.In some weak moments, I started feeling myself as a failure. This is not the first time I associated with the term failure. It's all started with one deep negative seed that got rooted in my mind.When I was studying postgraduation, my mother took me to an astrologer. She was worried ab ...

[Music] Good morning ladies and gentlemen. I'm going to talk about how to rewire your brain to overcome your fears. Fear is a very natural human being.All of us have some kind of fears. Some fears which we are aware of and some fears which are unknown. There's no person on this planet who can claim that he doesn't have any kind of fears.Only the magnitude or the feeling could be found. If you broadly look at what kind of fears surround us, one is the fear of rejection. Getting rejected in interview or also ...

Good morning everyone. Hope you're doing well right now. Can anyone name an exact moment their life changed.Anyone. You can raise your hand if you want to. Well, most of the people think that they can.Maybe it was the day they moved to a new country, switched schools, or made a life-changing decision. And for sure, those moments feel big, defining, and important. But what if I told you that the real turning points aren't the ones we really remember.What if the biggest changes in our lives have been happenin ...

Core Idea - Small, consistent habits can lead to significant life changes [1][2][8] - Focus on building habits that are simple and easy to maintain daily [2][4] - Emphasize the importance of patience and gradual progress in habit formation [5] Practical Application - Start with tiny habits, such as making your bed or reading one page daily [4] - Build upon initial successes by gradually increasing the intensity or duration of the habit [5] - Be patient and persistent, acknowledging that progress takes time and consistency [5] Psychological Impact - Building small habits can increase confidence and motivation [7][8] - Neuroplasticity explains how repeated actions create stronger neural pathways, making habits automatic [6][7] - Noticing positive changes resulting from small habits can further motivate continued effort [5]

Core Argument - The speech advocates for incorporating rhythm, specifically Indian classical music's "tal," as a form of brain exercise to improve cognitive functions, mental agility, and mental fitness [1][10] - The speech positions rhythm as a universal tool for managing stress, enhancing mental sharpness, and promoting overall well-being [20][21][22] Cognitive Benefits of Rhythm - Mental exercises like mindfulness and rhythmic activities such as "tal" can build focus, emotional resilience, and cognitive flexibility, strengthening the brain [3][18] - Practicing "tal" engages multiple brain areas, including the prefrontal cortex (problem-solving), motor areas, and cerebellum (balance and coordination), promoting neuroplasticity [18] - Rhythm can serve as a daily mental workout, similar to puzzles or memory games, but potentially more powerful [21] Rhythm in Clinical Interventions - Rhythm can be used in clinical interventions to manage conditions like obsessive-compulsive disorder (OCD) by restructuring neural pathways [13][15] - Techniques like drumming, tapping, and guided movement, as well as Emotional Freedom Technique (EFT), can help manage stress and anxiety [15][16][17] Cultural Significance of Rhythm - Rhythm is integral to various cultures, seen in Indian classical music and dance, Latin American salsa, East Asian Buddhist chants, and Western jazz, highlighting its universal presence [11][12] - "Tal" is not just a musical construct but a way of understanding and expressing life, originating in temples and structuring rituals, dance, and chants [11]

Core Argument - Change, whether physical or mental, originates in the mind, emphasizing the power of thoughts to influence outcomes [2][3] - The principle of cause and effect applies universally, including to thoughts, where inputs (thoughts) create outputs (results) [14][15][16] - Individuals are not defined by their past experiences or trauma but by their thoughts, urging proactive and intentional thinking [18][19] Neurological Basis of Thought - Repeated thoughts strengthen neural connections, making those thoughts easier and more automatic over time [5][6] - The brain is neuroplastic, meaning new neural pathways can be created intentionally through repetition and conscious effort [7][8] Sources of Negative Thought Patterns - Negative thought patterns often stem from personal experiences, which can be limiting if not properly contextualized [9][10][11] - Poor education, from various sources, can instill limiting beliefs disguised as truth, which individuals internalize and rationalize [12][13] Actionable Strategies - Question every mental seed before it takes root, exercising the power to challenge and reframe limiting beliefs [13] - Fiercely protect your inputs by guarding what you watch, hear, and who you associate with, to create desired outcomes [17]

[Música] Muito boa tarde, super poderosos. Que prazer estar aqui com vocês hoje. É uma honra para mim poder falar de um tema no qual eu acredito tanto, que é tão transformador, como ativar os seus superperes.Mas antes disso, eu quero trazer para vocês a história de um superherói, do meu superherói, do meu pai, Senr. Carmo José da Silva, que aos 53 anos de idade decidiu realizar um dos seus maiores sonhos, que era cursar a Universidade de Direito. O meu pai naquela altura passou por algumas dificuldades, mas ...

Core Insights - The PoNS Therapeutic Experience Program (PoNSTEP) study demonstrates long-term benefits of PoNS Therapy for gait deficits in individuals with Multiple Sclerosis (MS) [1][2] - The study results were presented at the 2025 Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting, highlighting the importance of treatment adherence for achieving clinically meaningful improvements [2][3] Study Details - The PoNSTEP study is an open-label, observational, interventional multi-center research study assessing adherence to PoNS Therapy for gait deficits in MS patients [5] - The study involved 43 MS participants and was conducted at six Centers of Excellence across the United States [5] - The primary endpoint is the maintenance of gait improvement from the end of supervised therapy to the end of unsupervised therapy, with secondary endpoints including maintenance of improvement over six months [5] Treatment and Mechanism - PoNS Therapy combines the Portable Neuromodulation Stimulator (PoNS) device with physical therapy, applied for 100-120 minutes per day [5][7] - The PoNS device delivers mild electrical impulses to the tongue and is indicated for short-term treatment of gait deficits due to mild-to-moderate MS symptoms [7][8] Clinical Impact and Recognition - The study provides the first clinical trial evidence of PoNS Therapy's long-term benefits for functional rehabilitation in the MS population [3] - There is growing recognition of PoNS Therapy's direct effect on the central nervous system and its targeted mechanism of action compared to other interventions [3] Reimbursement and Access - Helius Medical Technologies has successfully obtained initial reimbursement from federal and private payers, which is expected to lower barriers to prescribing PoNS Therapy [4] - The company is actively engaging with health insurance providers to expand access to PoNS Therapy for all individuals with MS [3][4]

Core Insights - BetterLife Pharma Inc. is focused on developing BETR-001, a non-hallucinogenic neuroplastogen aimed at treating psychiatric and neurological disorders [1][8] - BETR-001 has shown significant potential in promoting neuroplasticity, which is crucial for brain rewiring and forming new neuronal connections [2][4] - The company has received a composition of matter patent for BETR-001 and is preparing for IND filing and human trials projected for H1 2026 [7][9] Group 1: Scientific Developments - BETR-001 has been demonstrated to significantly induce the formation of new dendrites and spines in cultured rat brain cortical neurons, outperforming ketamine in these aspects [2][3] - The drug's neuroplasticity data suggests its effectiveness in treating various conditions such as depression, anxiety, PTSD, traumatic brain injury, migraines, and neuropathic pain [4][9] Group 2: Regulatory and Development Status - BetterLife has completed most of the required IND-enabling studies and has had a pre-IND meeting with the FDA [7] - The company is also developing BETR-002, which targets anxiety-related disorders, and is exploring strategic alternatives for other drug candidates [10]

Core Insights - Helius Medical Technologies, Inc. will present the final results of the PoNSTEP study, which confirms the efficacy of the Portable Neuromodulation Stimulator (PoNS) device for improving gait in individuals with multiple sclerosis (MS) [1][2] - The study highlights a statistically significant relationship between adherence to PoNS therapy and improvement in gait, indicating that consistent use leads to sustained benefits [3][4] Study Overview - The PoNSTEP study was a three-phase, real-world therapeutic experience designed to evaluate the impact of adherence on gait deficits and long-term outcomes in MS patients [3][8] - Participants underwent two weeks of supervised therapy, followed by 12 weeks of combined clinic and at-home use, concluding with a six-month follow-up to assess the durability of improvements [3][9] Key Findings - Stronger adherence to PoNS therapy resulted in better therapeutic outcomes, with highly adherent participants achieving over 6 points improvement in their Dynamic Gait Index (DGI) scores during the first 14 weeks [4][5] - More than 95% of participants maintained their level of improvement six months post-treatment, demonstrating the durability of the therapy's effects [5][7] Clinical Implications - The study provides evidence of the effectiveness of neuromodulation and neuroplasticity in rehabilitating gait deficits in MS patients, marking a significant advancement in treatment options for this population [7][10] - PoNS therapy is now accessible through insurance via the U.S. Department of Veterans Affairs and Department of Defense, with some commercial healthcare providers beginning to reimburse the device [7][12] About PoNS Device - The Portable Neuromodulation Stimulator (PoNS) is a non-implantable device that delivers neurostimulation through a mouthpiece, used in conjunction with physical rehabilitation exercises to improve balance and gait in MS patients [12][14] - The device is indicated for short-term treatment of gait deficits due to mild-to-moderate MS symptoms and is prescribed for patients aged 22 and older [12][13]