PD1/VEGF 双抗

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康方生物(09926):引领全球IO2.0,依沃西有望占据最大市场份额
Huafu Securities· 2025-08-09 08:36
Investment Rating - The report maintains a "Buy" rating for the company, expecting a relative increase of over 20% in stock price compared to the market benchmark index within the next six months [6][17]. Core Viewpoints - The company is leading the global progress with its product AK112, which is expected to capture the largest market share in the second-generation IO market [2][4]. - The broad-spectrum anti-cancer effects of PD-1 and VEGF targets are promising, with a significant existing market potential of nearly 60 billion USD globally [3]. - The company has already received approval for two indications of AK112 in China, making it the only PD-1/VEGF dual antibody product available globally [4]. Financial Forecast and Valuation - Projected revenues for the company from 2025 to 2027 are estimated at 35.18 billion, 57.65 billion, and 93.72 billion CNY respectively, with net profits expected to be -1.86 billion, 8.03 billion, and 29.66 billion CNY [6][8]. - The estimated peak overseas sales for AK112, after risk adjustments, could reach approximately 197 billion USD [6]. - The report calculates a reasonable market value of 222.8 billion HKD based on a DCF valuation with a WACC of 8.06% and a perpetual growth rate of 1% [6].