The LOI Aligns with Federal Priorities on Fentanyl Crisis, Artificial Intelligence, and Quantum TechnologyORLANDO, Fla., Dec. 18, 2025 (GLOBE NEWSWIRE) -- Nutriband Inc. (NASDAQ: NTRB) (NASDAQ: NTRBW) ("Nutriband" or the "Company"), a developer of transdermal pharmaceutical products including abuse-deterrent technologies, today announced the signing of a non-binding Letter of Intent ("LOI") with the Qvanta Group of Companies. The Qvanta Group comprises Qvanta LLC and its subsidiaries, Qvanta Foundry LLC and ...

MONTREAL, Dec. 18, 2025 (GLOBE NEWSWIRE) -- Knight Therapeutics Inc. (TSX: GUD) ("Knight"), a pan-American (ex-USA) specialty pharmaceutical company, announced today that Health Canada has approved WYNZORA®, a white uniform cream containing 0.05 mg/g of calcipotriol (CAL) and 0.5 mg/g of betamethasone dipropionate (BDP), indicated for the topical treatment of psoriasis vulgaris in adults and adolescents aged 12-17 years for up to 8 weeks.1 Knight obtained the Canadian rights to WYNZORA® through its June 202 ...

Key Points Eli Lilly's next-gen anti-obesity candidate hit it out of the park in a phase 3 study. This should help solidify the company's lead in this niche of the industry. Even after their strong run, Lilly's shares remain attractive at current levels. 10 stocks we like better than Eli Lilly › Can anyone stop Eli Lilly (NYSE: LLY)? The pharmaceutical leader has established itself as the leader in the fast-growing weight loss market. And although many other drugmakers are hot on its tail, Lilly ...

Group 1 - Novo Nordisk and Intuitive Surgical are both leaders in the healthcare sector but operate in different areas, with Novo Nordisk focusing on pharmaceutical drugs and Intuitive Surgical on robotic-assisted surgery devices [1] - Both companies have faced challenges this year, resulting in below-average stock-market performances, but there is potential for recovery in the coming years [2] Group 2 - Novo Nordisk's financial results have not met investor expectations, with a decline in top-line growth and a lowered outlook due to losing ground in the GLP-1 market, which is crucial for its revenue [4] - The company is expected to launch new products, including CagriSema, which, despite not meeting the target of 25% mean weight loss, achieved a competitive 22.7%, potentially aiding its position in the crowded GLP-1 market [5] - Recent and pending label expansions for semaglutide, including new approvals for reducing cardiovascular event risks and treating metabolic dysfunction-associated steatohepatitis, could enhance Novo Nordisk's sales growth [6] - Novo Nordisk's sales increased by 12% year over year to 229.9 billion Danish kroner ($36.2 billion) in the first nine months of the year, while net profit rose by 4% to 75.5 billion DKK ($11.9 billion) [7] Group 3 - Intuitive Surgical is expected to maintain its leadership in the robotic-assisted surgery niche despite facing increased competition [8] - Both Novo Nordisk and Intuitive Surgical have the potential to be long-term winners, with investment choices depending on individual risk tolerance [8]

Prescription pharmaceutical transdermal fentanyl is a valuable treatment for management of pain in opioid-tolerant patients, severe enough to require daily, around-the-clock, long-term opioid treatment for which alternate treatment options are inadequate. Illicit fentanyl and its core precursor chemicals have been designated as weapons of mass destruction to enable the US government to combat the manufacture and distribution by cartels and foreign networks that have flooded the US with illegal fentanyl. Nut ...

Core Insights - Viatris Inc. has announced four significant regulatory milestones in its global pipeline, highlighting advancements in research and development throughout 2025 [1][6][14] Group 1: Regulatory Approvals - The U.S. FDA has approved the company's octreotide acetate for injectable suspension, a generic version of Sandostatin LAR Depot, for treating acromegaly and certain cancer-related symptoms [6][14] - This approval marks the fourth injectable FDA approval for Viatris in 2025, alongside iron sucrose, paclitaxel, and liposomal amphotericin B, showcasing the company's ability to navigate complex regulatory pathways [3][14] - The FDA has accepted the New Drug Application (NDA) for a low dose estrogen weekly patch for contraception, with a target action date of July 30, 2026 [6][14] Group 2: Pipeline Developments - The investigational low dose estrogen weekly patch is designed for women with a BMI below 30 kg/m², delivering approximately 150 mcg of norelgestromin and 17.5 mcg of ethinyl estradiol per day [4][7] - The planned 505(b)(2) NDA for the patch is supported by positive results from the Phase 3 Luminous Study, demonstrating a favorable efficacy and safety profile [5][14] - The U.S. FDA has cleared the Investigational New Drug (IND) application for MR-146, a gene therapy candidate for neurotrophic keratopathy, with plans to initiate a Phase 1/2 clinical trial in the first half of 2026 [6][9][14] Group 3: International Developments - The Japan Pharmaceuticals and Medical Devices Agency has accepted the Japanese New Drug Application (J-NDA) for pitolisant in obstructive sleep apnea syndrome, supported by positive Phase 3 data [6][11][14] - The Phase 3 trial for pitolisant showed statistically significant improvements in excessive daytime sleepiness compared to placebo, indicating its potential effectiveness [11][14]

Core Insights - Pfizer has acquired global rights to an oral weight-loss drug from Fosun Pharma, aiming to enhance its position in the competitive weight management market [1][4] - The collaboration is potentially valued at over $2 billion, highlighting the growing interest in innovative medications developed in China, particularly GLP-1 drugs [5][12] Group 1: Licensing Deal Details - Fosun Pharma's subsidiary, Yao Pharma, has granted Pfizer an exclusive worldwide license for the oral GLP-1 receptor agonist YP05002, which is still in early-stage development [6][8] - The deal includes an upfront payment of $150 million, with additional potential payments of up to $350 million tied to clinical and commercial milestones, and sales-related payments that could total $1.59 billion, leading to a maximum deal value of approximately $2.09 billion [7][12] Group 2: Market Context and Competition - GLP-1 therapies have become a significant focus for global pharmaceutical companies, with Novo Nordisk's semaglutide generating $25.46 billion in sales and Eli Lilly's tirzepatide achieving $24.84 billion in sales in the first three quarters of 2025 [10] - The oral version of GLP-1 drugs, like YP05002, could offer advantages over injectables, potentially improving patient compliance due to convenience [11] Group 3: Fosun Pharma's Performance - Fosun Pharma reported an 18.09% increase in revenue from innovative drugs in the first three quarters, despite an overall revenue decline of 4.91% to 29.39 billion yuan ($4.17 billion) due to price pressures in China's drug procurement [14] - The partnership with Pfizer is seen as a significant milestone in Fosun Pharma's strategy for innovation and internationalization, potentially enhancing its global market presence [15] Group 4: Future Outlook - Fosun Pharma's focus on innovative drugs is expected to drive growth, as it continues to divest non-core assets and allocate resources to research and development [16] - The company's current price-to-earnings ratio of around 17 times suggests potential for multiple expansion compared to other established Chinese drugmakers [16]

INDIANAPOLIS, Dec. 18, 2025 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) today announced positive topline results from the ATTAIN-MAINTAIN trial. The Phase 3 study evaluated orforglipron, an investigational, once-daily oral small molecule glucagon-like peptide-1 (GLP-1) receptor agonist, for weight maintenance over 52 weeks after initial treatment for 72 weeks with the highest tolerated doses of Wegovy (semaglutide) or Zepbound (tirzepatide), in participants from SURMOUNT-5 who were offered the opportu ...

Core Insights - Eli Lilly's obesity pill, orforglipron, has shown promising results in maintaining weight loss for patients transitioning from injections like Zepbound and Wegovy in a late-stage trial [1][3][4] Group 1: Trial Results - The phase three trial involved over 300 patients who had previously taken Wegovy or Zepbound for 72 weeks, followed by a 52-week period where they were randomized to receive either the pill or a placebo [4] - Patients switching from Wegovy regained an average of only 2 pounds, while those switching from Zepbound regained about 11 pounds by the end of the trial [5] - The pill met its primary goal of demonstrating superior weight loss maintenance compared to placebo among patients who had plateaued while on injections [4] Group 2: FDA Approval and Market Potential - Eli Lilly has filed for FDA approval of orforglipron, which has received a priority review voucher that could expedite the review process [2] - Analysts suggest that positive trial results could allow Eli Lilly to capture market share from Novo Nordisk's semaglutide products, potentially impacting the competitive landscape [7] Group 3: Safety and Tolerability - The safety profile of the pill was consistent with previous studies, with common side effects being mild-to-moderate gastrointestinal issues [8] - Discontinuation rates due to side effects were 4.8% for those switching from Wegovy and 7.2% for those switching from Zepbound [9] Group 4: Market Forecast - Analysts predict that oral medications will capture a 24% share of the global weight loss drug market by 2030, valued at approximately $95 billion [12] - Eli Lilly's pill is expected to hold a 60% share of the daily oral segment, translating to around $13.6 billion, while Novo Nordisk's oral semaglutide is projected to have a 21% share [13]

年末各个地方集采仍在持续开展。 同期值得注意的是，推进的河北牵头京津冀赣化药集采规模再创新高，187个纳入品种中不乏水飞蓟 宾、复方氨酚烷胺、塞替派等重磅产品。其中水飞蓟宾胶囊2024年销售额6.98亿元，2025年上半年达 3.31亿元；维生素D滴剂作为首年约定采购量最大的品种，仅河北、江西两省填报总量就接近2400万 瓶，2024年销售额达18.88亿元。 2025 年末，地方联盟集采进入集中落地期，多省联动采购模式持续扩容，纳入品种均聚焦临床用量 大、市场规模高的核心品类，形成 "国家集采补位 + 地方特色覆盖" 的全方位采购体系。 本月，地方药品集采密集落地——河南牵头34种药品省际联盟集采、京津冀赣化学药品集中带量采购、 河北联盟集采到期接续采购等多项举措接连推进，地方联盟集采的扩面提速态势显著。 此外，国家医保局年初已明确规划，2025年将在地方层面开展具备专业特色的全国联盟采购预计达到20 个左右，包括中成药、中药饮片以及高值耗材等，预计2025年国家和联盟组织开展的药品集采品种将达 到700个。 本月初，河南省医保局启动省际联盟集采，覆盖 34 个市场关注度较高的品种，剂型分布呈现 "注射剂 ...