北京阳光诺和药物研究股份有限公司 （一）公司不存在《管理办法》等法律、法规和规范性文件规定的禁止实施 股权激励计划的情形，公司具备实施股权激励计划的主体资格。 （二）本次限制性股票激励计划所确定的激励对象具备《公司法》、《证券 法》、《公司章程》等法律、法规和规范性文件规定的任职资格；名单人员均不 存在《管理办法》、《上市规则》规定的禁止成为激励对象的情形，符合《激励 计划（草案）》规定的激励对象范围。公司 2025 年限制性股票激励计划激励对 象的主体资格合法、有效。 公司将在召开股东会前，在公司内部公示激励对象的姓名和职务，公示期不 少于 10 天。董事会薪酬与考核委员会在充分听取公示意见后，将于股东会审议 《激励计划（草案）》前 5 日披露对激励对象名单的审核意见及对公示情况的说 明。 （三）《激励计划（草案）》的制定、审议程序、内容符合《公司法》、《证 券法》、《管理办法》等有关法律、法规和规范性文件的规定；对各激励对象限 制性股票的授予安排、归属安排等事项未违反有关法律、法规和规范性文件的规 定，未侵犯公司及全体股东的利益。 （四）公司不存在向激励对象提供贷款、贷款担保或任何其他财务资助的计 划或安 ...

Core Viewpoint - The company held its 2024 annual general meeting and approved several key resolutions, including a share buyback plan and financial reports for the year [2][11]. Group 1: Meeting Details - The annual general meeting was held on April 29, 2025, at the Sheraton Hotel in Shanghai [2]. - All 12 current directors and 3 supervisors attended the meeting, along with the company secretary and CFO [3]. Group 2: Resolutions Passed - The following resolutions were approved: - 2024 Board of Directors' Work Report [4]. - 2024 Supervisory Board's Work Report [4]. - 2024 Financial Settlement Report [5]. - 2024 Profit Distribution Plan [5]. - Authorization for the Board to formulate a mid-term dividend plan [5]. - Special dividend plan for 2025 [5]. - External guarantee limit for 2025 [5]. - Reappointment of accounting firms for 2025 [5]. - Approval for foreign exchange hedging business limit for 2025 [5]. - Change of registered capital and amendments to the Articles of Association [6]. - Share buyback plan for A-shares [6][12]. - Approval of the 2025 H-share incentive trust plan [7]. - General authorization for the Board to issue debt financing instruments [8]. Group 3: Share Buyback Plan - The company plans to repurchase A-shares with a total fund of RMB 1 billion, estimating to buy back approximately 10,863,661 shares, which is about 0.38% of the total issued shares [12]. - The registered capital will decrease from RMB 2,887,992,582 to RMB 2,877,128,921 following the buyback [12]. Group 4: Debt Notification - The company notified creditors that they have 45 days from the announcement date to declare their debts and request repayment or guarantees [13]. - Specific documentation is required for debt declaration, including contracts and identification [14][15].

Summary of Key Points Core Viewpoint - WuXi AppTec experienced significant trading activity on April 30, with a total of 152,200 shares traded through block transactions, amounting to 9.2017 million yuan, at a price of 60.45 yuan per share, reflecting a premium of 2.16% over the closing price of the day [2]. Trading Activity - On April 30, there were 2 block trades for WuXi AppTec, totaling 152,200 shares and 9.2017 million yuan in transaction value [2]. - The stock's closing price on the same day was 59.17 yuan, which represented a decline of 2.12% [2]. - The daily turnover rate was 1.72%, with a total trading volume of 2.561 billion yuan and a net outflow of 246 million yuan in main funds [2]. - Over the past 5 days, the stock has increased by 5.25%, with a total net inflow of 72.5224 million yuan [2]. Financing and Ratings - The latest margin financing balance for WuXi AppTec is 3.906 billion yuan, which has decreased by 323 million yuan over the past 5 days, a decline of 7.63% [2]. - In terms of institutional ratings, 6 institutions provided ratings for the stock in the past 5 days, with Huatai Securities setting the highest target price at 93.30 yuan as of April 29 [2].

Investment Rating - The report maintains a "Buy" rating for WuXi AppTec, indicating a potential return of over 15% in the next 12 months [19]. Core Insights - WuXi AppTec reported strong financial performance for Q1 2025, with revenue increasing by 21.0% year-on-year to RMB 9.65 billion, and adjusted non-IFRS net profit rising by 40.0% to RMB 2.68 billion [1][2]. - The TIDES business segment experienced significant growth, with revenue soaring by 187.6% to RMB 22.4 billion, driven by expanded capacity and contributions from oral GLP-1 projects [2]. - Despite ongoing macroeconomic uncertainties, management reaffirmed its annual performance guidance, expecting a revenue growth of 10-15% and an expansion in adjusted non-IFRS net profit margin [1][2]. Financial Summary - For FY25E, revenue is projected at RMB 42.97 billion, reflecting a year-on-year growth of 9.5%, while adjusted net profit is expected to reach RMB 11.61 billion, a growth of 9.7% [4][16]. - The company’s unfulfilled contract amount grew by 47.1% year-on-year to RMB 52.33 billion by the end of Q1 2025, indicating a solid foundation for future growth [1]. - The report also highlights a decrease in the P/E ratio from 16.5 in FY24A to 15.0 in FY25E, suggesting improved valuation attractiveness [4][16]. Shareholder Returns - WuXi AppTec's board proposed a series of shareholder return plans, including maintaining a 30% annual cash dividend payout ratio and a one-time special dividend of RMB 10 billion in 2025 [3]. - The total proposed dividend and buyback plan amounts to nearly RMB 60 billion, representing 62% of the net profit attributable to shareholders for 2024 [3]. Valuation - The target price has been adjusted from RMB 94.05 to RMB 77.22 based on DCF valuation, reflecting a downside risk of 27.7% from the current price of RMB 60.45 [5][6].

Summary of the Conference Call for Zhaoyan New Drug Company Overview - **Company**: Zhaoyan New Drug - **Industry**: Pharmaceutical and Laboratory Services Key Financial Performance - **Q1 Revenue**: 411 million CNY, a year-on-year increase of 115.11% [2][3] - **Net Profit**: 41.12 million CNY, with a non-recurring net profit of 25.66 million CNY [2][3] - **Laboratory Segment Loss**: 41.34 million CNY, attributed to quarterly factors and industry pressures [2][3] - **Biological Asset Value Change**: Gain of 53 million CNY [2] - **Funds Management Contribution**: 16.62 million CNY [2] Order and Client Status - **New Orders**: Approximately 430 million CNY in new orders, a year-on-year increase [2][3] - **Backlog**: 2.2 billion CNY in backlog, stable compared to the previous quarter [2][3] - **Order Cancellations**: Decreased significantly, indicating a return to normal client status [2][14] Industry Dynamics - **Domestic IND Growth**: Slowed to 2.54%, but remains at a high level with stable order prices [2][5] - **FDA Policy on Animal Testing**: Proposed to use AI and organoids as alternatives, with limited short-term impact; ongoing monitoring of policy developments is necessary [2][5] - **Monkey Prices**: Stable due to supply-demand balance; domestic supply remains tight [2][7][8] Capacity and Expansion - **Non-Clinical Business Utilization**: High capacity utilization; new facility in Guangzhou nearing completion [2][9] - **M&A Activity**: Focused on enhancing laboratory service capabilities, with ongoing domestic and international acquisitions [2][10] Financial Management - **Accounts Receivable**: Good condition with high client creditworthiness; collection pressure is low [4][19] - **Cost Control**: Emphasis on managing costs and improving operational efficiency [15] Market Outlook - **Profitability Pressure**: No specific guidance on gross margin and net profit due to market demand and pricing uncertainties [4][12] - **Competition**: Industry competition remains stable, with some small companies exiting the market [19] Additional Insights - **Order Execution Cycle**: Typically ranges from 6 to 12 months, with no significant backlog currently [15] - **Emerging Fields**: New segments are growing faster than traditional ones, indicating a shift in market dynamics [22] This summary encapsulates the key points from the conference call, highlighting the financial performance, order status, industry dynamics, capacity expansion, financial management, market outlook, and additional insights relevant to Zhaoyan New Drug.

NO.1 赛力斯向港交所递交上市申请 4月28日，港交所文件显示，赛力斯集团股份有限公司向港交所提交上市申请书。今年3月底，赛力斯就宣布拟赴港上市，其彼时表示，发行H 股股票并上市是为了深入推进全球化战略布局，打造国际化资本运作平台，提高综合竞争力。H股募资将用于新能源汽车技术研发、海外市场 拓展及供应链优化。 点评：此次赴港上市旨在打造国际化资本运作平台，提高综合竞争力。H股募资将用于新能源汽车技术研发、海外市场拓展及供应链优化，这 将有助于赛力斯在全球新能源汽车市场中占据更有利的位置。 NO.2 昭衍新药一季度业绩同比扭亏为盈 4月28日，昭衍新药（HK06127，股价15.26港元）公布2025年第一季度业绩，公司实现营业收入约2.87亿元，同比减少11.54%；归属于上市公司 股东的净利润约4111.95万元，同比扭亏为盈；基本每股收益0.05元。公告称，净利增长主要系上年同期生物资产公允价值变动损失较多所致。 点评：尽管昭衍新药一季度营业收入有所下降，但净利润实现扭亏为盈，主要得益于上年同期生物资产公允价值变动损失的减少。这表明公司 在成本控制和运营效率方面取得了一定成效。 NO.3 耀才证券金融复 ...

但随着这个瓜的剧情发酵，舆情开始关注起了那位被医生搞大肚子的董医生，她的经历有些特殊。 父亲是某央企的总经理\党委副书记（副厅级），母亲是北京211高校的副院长（副处级），女儿高中就去美国读书，之后在哥伦比亚大学读了 一个经济学本科。 到这其实都还算正常，但之后回国通过协和4+4项目，四年后获得医学博士学位（M.D.）。看到这估计很多人就懵逼了，之前还是经济学本 科，回国读4年就变成医学博士了？ 我一开始也以为是通过父母权力寻租开的后门，结果去搜了一下发现协和这个4+4项目，专门收 非医学 类本科毕业生，但是要求本科是全球前 100的名校毕业，这个董医生是符合的，另外需要有2位医学领域的副教授写推荐信，学费也不便宜，一年15万。每年招30-45人。 感觉这个项目...是专门给背景人士的孩子留的后门，海外本科和高昂学费把普通家庭筛掉了，还要2个副教授写推荐信，这要不是在那个圈子里 的可不好找。 普通医学生的路径是5+3+3，5年本科，3年专硕，后面再规培3年当苦力。相比之下这位董医生国外回来4年就拿到博士学位，规培时间也压缩 到1年，之后就临床做手术了，而且还是在北京知名医院工作，直接把普通医学生羡慕坏了。 最 ...

从交易标的看，朗研生命成立于2010年7月14日，是一家药物研发生产商，专注于高难度首仿药、创新药研发、生产、销售一体化 服务，在研产品管线覆盖了心脑血管、肿瘤、消化、感染等适应症。 需要指出的是，本次交易对方为利虔、赣州朗颐投资中心（有限合伙）等朗研生命股东，而阳光诺和的实际控制人也是利虔，因 此此次交易构成关联交易。 星标 ★ IPO日报 精彩文章第一时间推送 4月24日晚间，北京阳光诺和药物研究股份有限公司（以下简称"阳光诺和"，688621.SH）发布公告称，公司拟通过发行股份 及可转换公司债券方式购买江苏朗研生命科技控股有限公司（以下简称"朗研生命"）100%股权，并向不超过35名特定投资者 发行股份募集配套资金。 经初步测算，本次交易预计构成重大资产重组，且构成关联交易，本次交易不会导致公司实际控制人发生变更。公司股票自2025 年4月25日开市起开始停牌，预计停牌时间不超过5个交易日。 制图：佘诗婕 曾收购失败 反观上市公司本身，阳光诺和于2021年上市，是一家专业的药物临床前及临床综合研发服务CRO，为国内医药企业和科研机构提 供全过程的一站式药物研发服务，致力于协助国内医药制造企业加速实现进 ...

Core Viewpoint - Sunshine Nuohua plans to acquire 100% equity of Jiangsu Langyan Life Science Technology Co., Ltd. through share issuance and convertible bonds, constituting a major asset restructuring and related party transaction, with no change in actual control [1][3]. Group 1: Acquisition Details - The acquisition target, Langyan Life, established in July 2010, focuses on high-difficulty generic drugs and innovative drug R&D, with product pipelines covering cardiovascular, oncology, digestive, and infectious diseases [3]. - The transaction involves shareholders including Li Qian and Ganzhou Langyi Investment Center, with Li Qian also being the actual controller of Sunshine Nuohua, thus constituting a related party transaction [3]. - Previous attempts to acquire Langyan Life were unsuccessful, with a failed acquisition plan announced in October 2022 [4][5]. Group 2: Financial Aspects - The transaction price is set at 1.611 billion yuan, with an additional 1.007 billion yuan to be raised for cash consideration and project expansions [5]. - Langyan Life's revenue was 510 million yuan in 2021 and 617 million yuan in 2022, with net profits of 37.54 million yuan and 85.13 million yuan respectively [5]. - Performance commitments from the sellers include net profits of no less than 95 million yuan, 125 million yuan, and 158 million yuan for 2023, 2024, and 2025, totaling at least 378 million yuan [5][6]. Group 3: Strategic Intent - The acquisition aims to extend Sunshine Nuohua's main business into the CDMO sector, creating an integrated service platform for clinical research and customized production, enhancing competitive strength and strategic layout [7]. - Sunshine Nuohua, listed in 2021, provides comprehensive drug R&D services, assisting domestic pharmaceutical companies in achieving import substitution and innovation [7]. - Despite a projected revenue increase of 15.7% to 1.078 billion yuan in 2024, net profits are expected to decline due to rising fixed costs and increased R&D investments [8].

Core Insights - The company reported a revenue of 544 million yuan for 2024, representing a year-on-year growth of 11.18%, while the net profit attributable to shareholders decreased by 54.59% to 17.08 million yuan [1] - The company is a new drug research and development service provider, increasing its R&D investment, which amounted to 47.26 million yuan, accounting for 8.68% of total revenue [1] - The compound annual growth rate (CAGR) for revenue from 2022 to 2024 is 6.70%, while the CAGR for R&D expenses is significantly higher at 40.21% [1] R&D and Technical Platforms - As of the end of 2024, the company has delivered a total of 55 candidate drug molecules to clients, with 10 new additions compared to 2023, and 47 of these are First-in-Class (FIC) projects, making up 85.45% of the total [1] - The company has established 12 core technology platforms since 2019, including CADD/AIDD, enzyme chemistry, photochemistry, and others, to enhance its technological capabilities [1] Business Development - The CADD/AIDD technology platform has supported 80 new drug projects, with 6 entering clinical Phase I and 1 entering clinical Phase II, and the number of clients utilizing CADD/AIDD services has reached 40 [2] - The company has intensified its marketing and promotional efforts, participating in 19 domestic and international exhibitions and forums during the reporting period, leading to progress in active customer numbers and new order amounts [2] - The company provides comprehensive services for global pharmaceutical and biotechnology companies, focusing on drug discovery, pharmaceutical process development, and customized/commercial production of active pharmaceutical ingredients and key intermediates [2]