同机理的针对黑色素生成的酪氨酸酶抑制剂Thiamidol已于2024年11月获我国药监局批准注册，成为自 2021年《化妆品监督管理条例》实施以来，首个亦是目前唯一获批注册的美白剂化妆品新原料，也是继 377之后，时隔12年国内获批注册的第二个美白剂化妆品原料。KT-939有望成为我国首个自主研发并获 批注册的美白剂化妆品新原料，实现我国在该领域完全自主知识产权的"零突破"，为我国乃至全球祛斑 美白化妆品市场提供新的选择。 截至本公告日期，KT-939已完成多项安全性和毒理学评估试验以及一项连续28天外用的人体功效试 验。试验结果表明，KT-939在功效性和安全性方面均表现良好。基于前期对KT-939与肽安密多 (Thiamidol)、苯乙基间苯二酚(377)等常用美白成分在功效性与安全性方面的对比，公司正积极推进KT- 939的注册申请准备工作，计划于明年第三季度正式向我国药监局递交注册申请。 开拓药业-B(09939)午前涨超8%，截至发稿，涨8.52%，报2.42港元，成交额963.88万港元。 消息面上，9月9日，开拓药业-B发布公告，自主研发的抑制黑色素生成的新型高效酪氨酸酶抑制剂KT- 939的人 ...

Group 1: DNV Group in China - DNV Group considers China as one of its most important regions globally, with the Chinese market accounting for approximately 28% of DNV's global business [2] - DNV operates five companies in China, with DNV (China) Ltd. serving as the headquarters, providing inspection and consulting services for new shipbuilding and offshore units [4] - DNV has issued over 8,000 certificates globally, with more than 6,000 certificates issued in China, serving various industries including automotive, aerospace, energy, and food [5] Group 2: Future Developments and Innovations - DNV is involved in around 30 joint development projects annually in China, focusing on new ship types and transformation solutions, particularly in the LNG shipbuilding sector [6] - The company has seen a nearly 30% increase in employee numbers over the past five years and emphasizes the training of local talent [6] - DNV aims to leverage Shanghai's advantages to enhance research and development in artificial intelligence, digital solutions, and alternative fuel technologies [6] Group 3: L'Oréal's R&D Center in China - L'Oréal's R&D center in Shanghai has become the largest and most comprehensive globally, with over 400 scientists and 372 patent applications expected in 2024 [7][10] - The center focuses on providing solutions for skin issues and benefits from Shanghai's thriving e-commerce ecosystem and digitalization [10] - L'Oréal is committed to investing in China, recently partnering with Veminsyn to develop innovative bioactive ingredients and launching a skin health management innovation center [11]