Business Overview - The company focuses on the dual strategy of "Traditional Chinese Medicine + Chemical Medicine" to drive growth through reforms in R&D, production, and sales [1] - The main business remains in drug R&D, production, and sales, with stable growth in the sales of contrast agents [1] - Sales revenue from iodine contrast agents is recovering after overcoming challenges from price drops due to centralized procurement [1] Product Development - The company has expanded its gadolinium contrast agent portfolio, now offering four MRI contrast agents [2] - Gadoxetic acid injection was approved in July 2024 and began procurement in April 2025, with further market share expected from gadobenate dimeglumine [2] - Sales revenue from antidiabetic products reached CNY 125.98 million in 2024, a year-on-year increase of 33.24% [3] Traditional Chinese Medicine Strategy - The company is enhancing its Traditional Chinese Medicine (TCM) segment through acquisitions, currently holding 59 TCM licenses [4] - The self-developed Jiuwei Zhenxin Granules is the first TCM approved for generalized anxiety disorder, aiming to establish a leading brand in this category [4][5] International Expansion - The company has successfully expanded its export markets, achieving overseas revenue of CNY 132.16 million in 2024, a 15.02% increase [6] - Products like iodine contrast agents have received registrations in EU countries, facilitating further international market penetration [6] R&D Progress - The company is restructuring its R&D resources and has made significant progress in various therapeutic areas, including CNS and endocrine drugs [7] - New product registrations include gadoxetic acid and paroxetine, with several products under review that have strong market potential [8] Integration of Acquired Companies - Following the acquisition of Tianyuan Pharmaceutical, the company is integrating operations across production, marketing, and finance to enhance management efficiency [9] Recent Developments in Associated Companies - The associated company, Shihe Gene, has made breakthroughs in multi-cancer early screening technology, achieving CE and FDA certifications for its products [10][11] - Shenzhen Yiwei Medical has developed a comprehensive AI-based service for brain diseases, focusing on early screening and rehabilitation [12]

Group 1: Company Strategy and Market Position - The company has successfully adjusted its strategy in response to the national drug centralized procurement, leading to a gradual recovery in sales of contrast agents, with a steady growth trend [1][2]. - The company aims to expand its market share by actively participating in centralized procurement while enhancing marketing efforts in non-procurement markets [3]. - The approval of Gadobutrol injection in July 2024 and its subsequent inclusion in the national centralized procurement is expected to enhance the company's market presence [2]. Group 2: Product Development and R&D Progress - The company has diversified its gadolinium-based contrast agents, now offering four MRI contrast agents, which helps meet various clinical needs and enhances market competitiveness [1][2]. - Recent approvals include Gadobutrol and other formulations, with ongoing evaluations for multiple products that target significant therapeutic areas [6][7]. - The company is focusing on integrating R&D resources and improving efficiency to support its strategic expansion in various therapeutic fields [6]. Group 3: International Market Expansion - The company achieved overseas revenue of 132.16 million yuan in 2024, marking a 15.02% increase year-on-year, with products successfully entering markets in South America, Africa, and Asia [4]. - The completion of EU GMP and Brazil ANVISA GMP certifications is expected to accelerate the internationalization of the company's contrast agents [4]. Group 4: Financial Performance and Future Outlook - The company anticipates further revenue growth from the upcoming centralized procurement of Gadobutrol and Gadobenate dimeglumine, which are expected to enhance brand influence [2][3]. - The company is also exploring opportunities in the overseas market, particularly in the EU, where several products have received registration [4]. Group 5: Subsidiary and Partner Developments - The acquisition of Tianyuan Pharmaceutical has led to successful integration into the group management system, focusing on enhancing operational efficiency across various departments [10]. - Recent advancements by partners, such as the launch of innovative cancer screening technologies by Shihe Gene, indicate a positive trend in the healthcare sector [11][12].

Group 1: Company Overview - Beilu Pharmaceutical's subsidiary, Shenzhen Yiwei Medical Technology Co., Ltd., focuses on brain disease early screening, precise diagnosis, and rehabilitation training, being the only AI enterprise in China with NMPA Class III certification in both neurodegenerative and cerebrovascular diseases [1] - Yiwei Medical's core products target stroke, Alzheimer's disease, cognitive disorders, and developmental disorders in youth, providing comprehensive solutions for screening, diagnosis, and rehabilitation [1] Group 2: National Policy Support - Recent national policies have significantly supported the development of precision diagnosis for brain diseases, aiming to train 500-1000 professionals annually and establish over 2100 cognitive disorder diagnosis centers by 2025 [2] - The National Health Commission emphasizes autism screening and intervention for children, enhancing screening, diagnosis, and intervention rates [3] Group 3: Product Development - Yiwei Medical has launched three main products: - Yiwei Brain Doctor, the first AI medical software for early Alzheimer's diagnosis, with both NMPA Class III and CE certifications [5] - Yiwei Smart Brain, a one-stop AI-assisted diagnosis platform for stroke, achieving dual certification from NMPA and FDA [5] - Yiwei Digital Therapy, integrating eye-tracking and VR technology for cognitive assessment and rehabilitation [5] Group 4: Business Model - Yiwei Medical offers a full-cycle service from screening to rehabilitation, collaborating with over 200 hospitals and health institutions, and exploring diverse revenue streams [6] - The company has introduced a comprehensive "brain routine" health check package and established digital rehabilitation centers in communities [6] Group 5: Financial Performance - In 2024, Beilu Pharmaceutical's revenue from contrast agents reached CNY 58.80 million, a 9.87% increase; diabetes products generated CNY 12.60 million, up 33.24%; while raw materials saw a decline of 20.83% to CNY 9.00 million [9] - The company anticipates continued growth across its business segments in 2025 [9] Group 6: International Expansion - Beilu Pharmaceutical's overseas revenue reached CNY 13.22 million in 2024, marking a 15.02% increase, with successful product exports to South America, Africa, and Asia [11] - The company is advancing its internationalization efforts with certifications in the EU and plans for further market expansion in Southeast Asia [11]

Group 1: Business Performance and Revenue - In 2024, the company achieved sales revenue of CNY 58,804.95 million for contrast agents, a year-on-year increase of 9.87% [1] - Sales revenue for hypoglycemic products reached CNY 12,598.34 million, growing by 33.24% year-on-year [1] - The company reported a decline in raw material sales revenue to CNY 9,003.14 million, down by 20.83% [1] - Sales revenue for traditional Chinese medicine preparations was CNY 16,844.68 million, reflecting a year-on-year growth of 19.65% [1] - The company’s overseas revenue for 2024 was CNY 13,216.14 million, marking a 15.02% increase [4] Group 2: Strategic Developments - The company continues to implement a "chemical + traditional Chinese medicine" dual-driven strategy, focusing on contrast agents, hypoglycemic drugs, and central nervous system traditional Chinese medicine [1] - The construction of the Cangzhou Phase III raw material production project has been completed, enhancing the production capacity for gadolinium and iodine contrast agents [2] - The Bozhou production base is progressing, with the first phase expected to start trial production and process validation within the year [3] Group 3: Market Expansion and Product Development - The company is expanding its market presence internationally, with successful exports of contrast agents and raw materials to South America, Africa, and Asia [4] - The company’s subsidiary, Haichang Pharmaceutical, is one of the few domestic producers with iodine contrast agent production qualifications, with an annual capacity of 1,000 tons [2] - The "MERCURY non-invasive blood test" technology developed by the affiliated company, Shihe Gene, allows for the screening of nine types of cancer from a single blood sample [7]

Group 1: Company Overview and Financial Performance - Beilu Pharmaceutical's contrast agent products generated sales revenue of 58,804.95 million yuan in 2024, representing a year-on-year growth of 9.87% [1] - The company achieved EU GMP and Brazil ANVISA GMP certifications for its production lines, supporting ongoing business growth [1] - The company plans to continue expanding its global market presence in 2025, focusing on steady growth in its contrast agent business [1] Group 2: Product Development and Innovation - The company has actively completed the bidding and registration processes for iodinated contrast agents, including Iohexol and Iopamidol [1] - In July 2024, the company received approval for Gadobutrol injection, which has been included in the national procurement list, enhancing market share and brand influence [1] Group 3: Medical Technology and Product Offerings - Yiwei Medical has launched three main products: - Yiwei-Brain Doctor, the first AI medical software for early Alzheimer's diagnosis, certified by both the National Medical Products Administration and CE [2] - Yiwei-Ruibrain, a comprehensive AI-assisted diagnosis platform for stroke, with dual certification from the National Medical Products Administration and FDA [2] - Yiwei-Digital Therapy, a cognitive assessment and rehabilitation product integrating eye-tracking and VR technologies [2] Group 4: Business Model and Market Strategy - Yiwei Medical focuses on precision diagnosis and treatment of brain diseases, offering a full-service model from screening to rehabilitation [3] - The company collaborates with health check institutions to provide a comprehensive "brain routine" health check package [3] - Yiwei Medical is exploring additional business models to expand market coverage and increase revenue streams [3] Group 5: Recent Developments in Partner Companies - Shihe Gene has made significant advancements in multi-cancer early screening technology, utilizing ultra-low depth whole genome sequencing and AI models [4] - The "Shihe Eagle Eye" product can screen for nine types of cancer with a single blood sample, significantly improving screening efficiency [4] - The product has received CE certification in the EU and breakthrough device designation from the FDA, outperforming international counterparts [4] Group 6: Industry Position and Competitive Advantage - Haichang Pharmaceutical is one of the few domestic companies with production capacity for iodinated contrast agent raw materials, with an annual output of 1,000 tons [5] - The recent approvals for Iopamidol and Iopromide raw materials enhance the company's competitive edge and product diversity [5]