Group 1 - The stock of Quan Shi International (00381) closed at HKD 0.22 on December 19, 2025, with a 0.93% increase from the previous trading day [1] - The stock opened at HKD 0.22, reached a high of HKD 0.22, and a low of HKD 0.21, with a trading volume of HKD 340,300 [1] - Over the past 52 weeks, the stock's highest price was HKD 1.72 and the lowest was HKD 0.20 [1] Group 2 - Quan Shi International announced a supplementary publication regarding its 2024 annual report, indicating the completion of a placement of convertible bonds totaling HKD 45 million on February 6, 2024, with net proceeds of approximately HKD 44.5 million [1] - Approximately HKD 30 million of the proceeds from the convertible bonds will be used for the construction of a traditional Chinese herbal medicine planting base in Hubei, and about HKD 10 million will be allocated for establishing a new production line for Chinese medicine pieces [1] - On September 30, 2024, the company completed the placement of 470 million ordinary shares, raising net proceeds of approximately HKD 51.3 million, with HKD 51 million used to repay outstanding amounts on the Hubei convertible bonds [1] - The company issued shares to creditors on May 17 and October 10, 2024, to settle debts, involving amounts of approximately HKD 19.2 million and HKD 7.98 million, respectively [1] - As of December 31, 2024, all proceeds have been fully utilized as intended, and the board confirmed that this supplementary information does not affect other contents of the 2024 annual report [1]

长期以来，人们一直认为肺癌是吸烟者的疾病。然而，随着世界许多国家和地区的烟草使用量的下降，一个令人担忧的趋势出现了： 从不吸烟者患肺癌的比例正 在上升 。 撰文丨王聪 编辑丨王多鱼 排版丨水成文 肺癌 是全世界发病率最高的癌症 ，也是全世界癌症死亡的最主要原因，据 世界卫生组织国际癌症研究机构 （IARC） 于 2024 年 发布的最新评估数据，肺癌每 年新增 248 万例，导致 180 万人死亡 。 从不吸烟者肺癌 （LCINS） 约占所有肺癌病例的 25%，这类肺癌对女性的影响尤为严重，尤其是亚裔女性，而且在东亚国家比在西方国家更为普遍。 一项发表于 Nature 期刊的最新研究，提供了令人信服的基因组证据，表明了 空气污染、 传统中草药以及其他环境因素是从不吸烟者肺癌的主要潜在因素。 | 国际顶尖学术期刊 | Nature | 。论文通讯作者为美国国家癌症研究所 | Maria Teresa Landi | | 研究员和加州大学圣地 | | | | --- | --- | --- | --- | --- | --- | --- | --- | | 该研究以： 亚哥分校 | The mutagenic f ...