布瑞基奥仑赛注射液(FKC889)
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深圳生物医药产业基金布局细胞治疗领域 拟参与复星凯瑞A轮融资,“输血”6亿元
Mei Ri Jing Ji Xin Wen· 2025-10-18 02:39
Core Viewpoint - Fosun Pharma's subsidiary, Fosun Kairui, is raising funds through a Series A financing round, with Shenzhen Biopharmaceutical Industry Fund committing to invest a total of 600 million yuan, aiming to enhance its operational capabilities and product pipeline [1][2]. Financing Details - The financing agreement involves a total investment of 600 million yuan, with a pre-money valuation of 2.2 billion yuan for Fosun Kairui [1]. - The investment will be made in three phases: an initial payment of 300 million yuan, followed by two subsequent payments of 200 million yuan and 100 million yuan, linked to specific milestones [3]. Financial Performance - Fosun Kairui is projected to generate revenues of 328 million yuan in 2024, with a net loss of 337 million yuan. For the first half of 2025, revenues are expected to be 220 million yuan, with a net loss of 161 million yuan [1]. - The company has yet to achieve profitability due to high treatment costs and limited insurance coverage for CAR-T therapies [1]. Product Development - Fosun Kairui's lead product, Aikeda (Acilin), is the first CAR-T therapy approved in China, currently approved for two indications and undergoing clinical trials for a third indication [1][2]. - The second CAR-T product, FKC889, has had its drug registration application accepted for treating acute lymphoblastic leukemia [2]. Market Context - The CAR-T market in China is becoming increasingly competitive, with seven approved CAR-T products primarily targeting large B-cell lymphoma and multiple myeloma, leading to a phenomenon of homogenized competition [4]. - The sales performance of competing CAR-T products, such as the one from King’s Ray Biotech, indicates a growing market, with significant sales figures reported [3]. Strategic Focus - Fosun Kairui aims to focus on clinical needs and expand the value of its indications through real-world research, rather than following popular targets in the CAR-T space [5].