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一品红创新药“虚火”高悬:五年研发投入近11亿元仅资本化1300万元,学术推广费近50亿元难挽业绩颓势|创新药观察
Hua Xia Shi Bao· 2025-06-17 12:04
Core Viewpoint - The stock price of Yipinhong (300723.SZ) has seen significant fluctuations, with a notable increase of 51.54% from May 17 to June 16, 2025, driven by market interest in its innovative drug AR882, which is currently in Phase III clinical trials [2][4]. Financial Performance - In 2024, Yipinhong reported a net loss of 540 million yuan, a drastic decline of 392.52% compared to a profit in 2023 [6]. - The company's operating revenue fell to 1.45 billion yuan in 2024, down 42.07% from 2.503 billion yuan in 2023, primarily due to increased market competition and policy impacts leading to price reductions [7][8]. Business Segments - The core businesses of pediatric and chronic disease medications both experienced revenue and gross margin declines in 2024. Pediatric drug revenue was 936 million yuan, a decrease of 39.04% year-on-year, while chronic disease drug revenue was 370 million yuan, down 51.97% [9][11]. - The gross margin for pediatric drugs decreased by 12.19 percentage points, and for chronic disease drugs, it fell by 42.29 percentage points [12]. Non-Recurring Losses - Yipinhong's non-recurring losses amounted to 251.1 million yuan in 2024, a significant drop from a gain of 64.63 million yuan in 2023, primarily due to a 266 million yuan refund related to medical insurance violations and asset impairments [13]. Government Subsidies - The company received only 16.01 million yuan in government subsidies in 2024, a decline of 79.8% from 2023, indicating a significant reduction in revenue-related government support [14]. Sales and Marketing Expenses - Yipinhong's reliance on a single sales model, the academic promotion model, has led to high sales expense ratios, which were 44.88% in 2023 and 34.86% in 2024, compared to the industry average of 24.73% and 28.80% [19][20]. - Despite a significant increase in R&D expense ratio to 22.40% in 2024, actual R&D spending only rose by 24 million yuan to 325 million yuan [20][21]. R&D and Capitalization - Over the past five years, Yipinhong has spent nearly 1.1 billion yuan on R&D, but only 13 million yuan was capitalized last year, raising concerns about the uncertainty and risk associated with its R&D projects [21][22]. Market Outlook - The market's increasing competition and the company's reliance on a few products for revenue generation may weaken its resilience against market fluctuations, posing challenges for future performance [14][22].