Core Viewpoint - Shanghai Serum Bio-Technology Co., Ltd. reported a steady growth in revenue and net profit for the first half of 2025, with a focus on the development and production of antiserum and antitoxin products, particularly in the field of biological safety and toxin treatment [1][2]. Company Overview and Financial Indicators - The company achieved an operating income of 100.82 million yuan, a 2.82% increase compared to the same period last year [2][3]. - The total profit reached 37.77 million yuan, reflecting a 1.92% increase year-on-year [2][3]. - The net profit attributable to shareholders was 32.98 million yuan, up 2.07% from the previous year [2][3]. - The net assets attributable to shareholders were 1.11 billion yuan, a 1.03% increase from the end of the previous year [2][3]. Industry and Main Business Situation - The company operates in the pharmaceutical manufacturing industry, specifically in the biopharmaceutical sector focusing on antiserum and antitoxin production [4][5]. - The company is a leader in the antiserum and antitoxin field, producing unique products such as antivenom for snake bites and tetanus immunoglobulin, which have reached advanced production levels [4][5]. - The antivenom products are the only effective treatments for snake bites in China, with no direct substitutes available [4][5]. Research and Development - The company is actively engaged in the research and development of new antivenom products, including specific antivenoms for viper bites and bee venom, which are currently in various stages of clinical trials [10][12]. - The company has established a strong technical foundation in the production of antiserum and antitoxin, with proprietary technologies in antigen purification, immune response enhancement, and virus inactivation [15][18]. - New projects include the development of broad-spectrum antivenom and recombinant snake venom coagulants, aimed at improving treatment options for snake bites and enhancing surgical hemostasis [10][12][13]. Market Expansion - The company has strengthened its market presence through educational initiatives and improved public awareness regarding snake bite treatment, enhancing the accessibility of its products [13][14]. - The company is also working on improving the procurement and distribution of its rabies antiserum, which has shown significant results in clinical applications [14].

Group 1 - The establishment of designated hospitals for snakebite treatment in Guangzhou has significantly improved the treatment outcomes for snakebite patients [2] - The number of designated snakebite treatment hospitals in Guangzhou has increased from 2 to 11 since September 2022, ensuring that patients can receive timely medical care close to their location [2] - Hospitals are well-stocked with various types of antivenom, including those for pit viper, five-step snake, cobra, and silver-ringed snake, alleviating public concerns about antivenom shortages [2] Group 2 - City representatives suggest enhancing public awareness regarding snakebite prevention, emergency response, and treatment, including promoting designated hospitals and self-rescue techniques [3] - There is a proposal to conduct scenario simulation classes in schools and communities to educate parents and students on snakebite treatment knowledge [3] - Continuous monitoring and advocacy for increased publicity and emergency response capabilities at designated hospitals are emphasized to ensure public safety [3]

Core Viewpoint - The article highlights the rising concern over snakebite incidents in China, emphasizing the importance of immediate medical response and the availability of antivenom in hospitals [1][2]. Summary by Sections Snakebite Statistics and Trends - China experiences approximately 250,000 to 280,000 cases of snakebites annually, predominantly affecting middle-aged and elderly individuals [1]. - The peak activity period for snakes is from April to October, with the highest incidence of bites occurring from July to September [1]. First Aid Guidelines - Key steps for first aid after a snakebite include moving away from the danger, observing the snake's characteristics, removing jewelry and tight clothing, minimizing movement, and calling emergency services immediately [1][2]. Antivenom Availability - There are four types of antivenom available in China: antivenom for cobra, viper, silver ring snake, and five-step snake [2]. - Different snake species require specific antivenom, with common venomous snakes in the region including the short-tailed viper, silver ring snake, cobra, and king cobra [2]. Hospital Resources in Changsha - Various hospitals in Changsha have stocked different types of antivenom: - Xiangya Hospital of Central South University has four types of antivenom [3]. - Hunan Provincial People's Hospital also stocks four types of antivenom [5]. - Hunan University of Traditional Chinese Medicine First Affiliated Hospital has four types of antivenom available [6]. - Changsha Central Hospital has two types of antivenom and can procure others quickly [8]. - Other hospitals like Changsha First Hospital and Changsha Fourth Hospital also maintain stocks of various antivenom types [9][10].

Core Points - A tourist's death due to an unknown animal bite has sparked widespread public discussion [1] - The family is demanding video footage and has communicated with the involved parties [2] - The Hainan Provincial Health Commission has intervened in the investigation [3] Group 1: Medical Response and Treatment - Experts indicate that if the bite was from a venomous snake, it is a treatable condition with existing antivenom [5] - Timely medical intervention is crucial; delays can lead to irreversible damage [5][35] - The first hospital did not have antivenom readily available, raising concerns about emergency preparedness [14][19] Group 2: Diagnosis Challenges - Diagnosing snake bites is complex and relies on various factors including the type of snake and symptoms presented [8][9] - Symptoms of different snake venoms vary significantly, complicating diagnosis [9] - The initial diagnosis at the first hospital was inconclusive, leading to a transfer to a second facility [7] Group 3: Antivenom Availability and Guidelines - There are only four main types of antivenom available, and not all hospitals stock them due to low incidence rates of snake bites [15][19] - The World Health Organization recommends that antivenom should be part of treatment protocols in primary healthcare settings [14] - A unified network for snake bite treatment is suggested to improve response times and outcomes [25] Group 4: Public Awareness and Education - Public awareness campaigns are encouraged to help individuals identify snakes and seek timely medical help [33][34] - The importance of rapid treatment within the first few hours post-bite is emphasized to improve survival rates [36]