在关于口腔黏膜脱落的各类猜测中，牙膏中的月桂醇硫酸酯钠（SLS）表面活性剂常常成为焦点，不少 消费者将其视为口腔黏膜脱落的"罪魁祸首"。事实上，对于SLS的安全性，要理性客观看待。 正常脱皮无须恐慌 口腔黏膜是人体第二大黏膜组织，由复层鳞状上皮构成，有着完整的代谢周期：基底细胞层持续进行有 丝分裂，新生细胞不断向表层迁移并逐渐角化，最终自然脱落。研究显示，口腔黏膜更新速度较快，且 口腔黏膜上皮表层每3小时左右便会更替一次，每天更替约8次，黏膜表面黏附的细菌也会随之脱落，是 一种正常的保护机制。不过，这种正常的脱皮现象通常不易被察觉。 如果刷牙后偶尔感觉口腔黏膜上有白皮脱落下来，没有其他不适，这种情况可能是牙膏中一些成分将自 然脱落的口腔黏膜连接成片，无须过度担心。但是如果经常、反复出现成片黏膜脱落，尤其伴随水疱、 红肿、疼痛等不适，要引起注意，及时就医。 表面活性剂的真相 （来源：中国消费者报） 图：资料图片 近期，网络上关于"牙膏导致口腔'脱皮'"的讨论引发广泛关注，让不少消费者心生困扰，进而对牙膏安 全产生疑虑。其实，口腔黏膜脱落并非都是异常信号，其背后涉及口腔组织正常代谢规律、刷牙方式、 身体健康状况等 ...

Core Insights - The article discusses the potential adverse effects of Sodium Lauryl Sulfate (SLS) found in many toothpaste products, particularly its association with oral health issues such as mouth ulcers and irritation [1][7][11] Group 1: SLS Overview - SLS, or Sodium Lauryl Sulfate, is a surfactant commonly used in toothpaste to create foam, aiding in the removal of food debris and plaque [3][5] - It is also found in various personal care products, including shampoos, body washes, and cleaning agents, due to its low cost and effective cleaning properties [5] Group 2: Health Implications - SLS has been linked to increased incidence and severity of oral ulcers, with studies indicating that individuals using SLS-containing toothpaste experience more pain and longer healing times [7][9] - Some research suggests that switching to SLS-free toothpaste can reduce the frequency and duration of mouth ulcers, highlighting the sensitivity of oral mucosa to SLS [9][11] Group 3: Recommendations for Sensitive Individuals - Dental professionals recommend that individuals prone to mouth ulcers or with sensitive skin avoid SLS-containing products and opt for SLS-free alternatives [11] - SLS is generally considered safe for most users, with concentrations in toothpaste typically ranging from 0.5% to 2%, but warnings are advised for those experiencing irritation [11]