撰文丨王聪 编辑丨王多鱼 排版丨水成文 铁死亡 （Ferroptosis） 是 2012 年由哥伦比亚大学 Brent Stockwell 实验室发现的一种铁依赖性的新型细胞程序性死亡方式，由过度堆积的 过氧化脂质 （peroxidized lipids） 诱导发生，其形态特征，作用方式以及分子机制与其他程序性死亡方式截然不同。同时，细胞中存在多个对抗铁死亡的防御途径， 例如 GPX4 通过 谷胱甘肽 （GSH） 特异性催化过氧化脂质来抑制铁死亡的发生； FSP1 通过产生 辅酶 Q10 （CoQ10） 的抗氧化形式促进癌细胞对铁死亡的抵抗。 然而，目前我们对于调控 FSP1 表达和稳定性的机制仍知之甚少，这阻碍了将 FSP1 作为癌症治疗靶点的研究。 近日， Nature Structural & Molecular Biology 和 Nature Cell Biology 同时发表了两项研究， 揭示了 维生素 B2 代谢 与 铁死亡抗性 之间的关联，为基于铁死 亡的癌症治疗带来了新思路。 2026 年 3 月 13 日，加州大学伯克利分校的 研究人员在 Nature 子刊 Nature Structur ...

Group 1: Company Highlights - Zhonghua Yantu is a leading geotechnical and underground engineering service provider in China [2] - Shandong Molong specializes in oil drilling machinery and is a key supplier to CNOOC [2] - Sinopec Oilfield Services ranks fourth globally in the oil service industry [2] - Beiken Energy is a comprehensive service provider for oil and gas resource development [2] - Huibo Pu focuses on oil and gas engineering services and has gained access to multiple oil and gas companies in the UAE, Kuwait, Iraq, and Kurdistan [2] - Maohua Shihua is primarily engaged in petrochemicals [2] Group 2: Market Trends - The market is seeing a rise in state-owned asset securitization and leveraging of state-owned funds [2] - Companies like Wuhan Holdings and Sanxia New Materials are under the control of state-owned assets [2] - The coal enterprise Dayou Energy is undergoing strategic restructuring [2] Group 3: Financial Performance - Haizhou Group's net profit is expected to increase by 625.83% to 756.71% year-on-year [4] - New Link Electronics reported a net profit growth of 421.43% in Q3, attributed to increased investment income [5] - North China Holdings, a major mining vehicle manufacturer, anticipates a net profit increase of 56.9% to 70.74% year-on-year [5] Group 4: Industry Developments - The company plans to acquire an 81.8091% stake in Guangdong Changxing Semiconductor Technology Co., enhancing its control over the semiconductor sector [4] - The domestic market for artificial meat is gaining traction, with companies like Beyond Meat experiencing significant stock price increases [3] - The photovoltaic sector is witnessing a revenue growth of 71.04% year-on-year, with companies like Bluefeng Biochemical leading the way [7]