Group 1 - The "China Type 1 Diabetes Ecological Co-construction Cooperation Alliance" was officially launched, marking a significant collaboration between Shenzhen YHLO Biotech Co., Ltd. and Sanofi in the management of Type 1 diabetes [1][3] - This partnership aims to transform the treatment model from "passive treatment" to "active intervention," enhancing early screening, diagnosis, and integrated treatment levels for Type 1 diabetes in China [3][4] - YHLO's precise detection solutions provide reliable diagnostic bases for doctors, forming a complete "diagnosis + treatment" loop in collaboration with Sanofi's innovative therapeutic drugs [4][6] Group 2 - The collaboration is expected to win patients and their families a valuable "buffer period" through early screening and precise intervention, effectively delaying disease progression and allowing patients to navigate critical life stages more smoothly [6][7] - YHLO has been recognized as a "National Manufacturing Single Champion Enterprise," showcasing its strong product capabilities and leadership in the autoimmune diagnostic field [7][9] - The global autoimmune disease diagnostics market is projected to grow from approximately $14.2 billion in 2022 to $17.9 billion by 2028, with a compound annual growth rate (CAGR) of 3.9% [8][9]

Core Viewpoint - The company reported a significant decline in revenue and net profit for the first half of 2025, primarily due to domestic market pressures and increased competition, while overseas business showed growth potential [1][2]. Financial Performance - In H1 2025, the company achieved revenue of 808 million yuan, a year-on-year decrease of 15.79%, and a net profit of 26 million yuan, down 84.82% year-on-year [1]. - In Q2 2025, revenue was 391 million yuan, reflecting a 26.12% year-on-year decline, with net profit at 16 million yuan, down 84.93% year-on-year [1]. - The company's main business revenue was 671 million yuan, a decrease of 14.98% year-on-year, with domestic revenue at 542 million yuan, down 21.08%, while overseas revenue grew by 26.00% to 129 million yuan [2]. Business Segments - The self-produced chemiluminescence business generated 603 million yuan in revenue, down 15.87% year-on-year, with a gross margin of 61.58% [2]. - The company installed 1,090 self-produced chemiluminescence instruments in H1 2025, with 546 units in the domestic market and 544 units overseas [3]. - The pipeline business saw a remarkable growth of 54.05%, with 57 new installations, including 11 new contracts for the self-developed iTLA Max pipeline [3]. Strategic Initiatives - The company is advancing its "AI + IVD" strategy, focusing on product transformation and upgrades based on clinical needs [4]. - In the diabetes sector, the company launched the PIFI digital platform for standardized assessment of pancreatic function, utilizing large-scale clinical data and machine learning [4]. - The company has developed an intelligent interpretation system for autoimmune diseases, achieving a recognition accuracy of 91.3% and deployed it in over 30 top-tier hospitals [4]. Investment Outlook - The company maintains a "buy" rating, with projected revenues of 1.851 billion yuan, 2.167 billion yuan, and 2.542 billion yuan for 2025-2027, reflecting a year-on-year growth of -8.0%, 17.1%, and 17.3% respectively [5]. - Expected net profits for the same period are 114 million yuan, 300 million yuan, and 415 million yuan, with corresponding EPS of 0.20, 0.53, and 0.73 yuan [5].

Investment Rating - The report maintains a "Buy" rating for the company [9] Core Views - The company's revenue for the first half of 2025 was 808 million yuan, a year-on-year decrease of 15.79%, with a net profit attributable to the parent company of 26 million yuan, down 84.82% year-on-year [2] - Domestic business is under short-term pressure due to medical insurance cost control policies, while overseas business continues to grow significantly, with overseas revenue increasing by 26.00% to 129 million yuan [3] - The company's "AI + IVD" strategy is being implemented, enhancing product lines in diabetes and autoimmune disease diagnostics [5] Financial Performance - In the first half of 2025, the company's gross profit margin was 61.58%, with the chemical luminescence reagent business gross margin at 80.15% [3] - The company expects revenues of 1.85 billion yuan in 2025, with a projected net profit of 114 million yuan, reflecting a year-on-year decline of 62.1% [11] - The earnings per share (EPS) is projected to be 0.20 yuan in 2025, with a price-to-earnings (P/E) ratio of 77x [9][11] Business Segments - The company installed 1,090 chemical luminescence instruments in the first half of 2025, with a notable increase in the number of production lines, which grew by 54.05% year-on-year [4] - The company has deepened its customer coverage, with over 6,210 domestic medical institutions, including more than 1,260 top-tier hospitals [4] Strategic Initiatives - The company has launched the PIFI digital platform for diabetes, enhancing clinical diagnosis through machine learning [5] - The development of an intelligent interpretation system for autoimmune diseases has improved accuracy to 91.3% [5] - The integration of AI technology in laboratory automation is being explored to enhance operational efficiency [8]