登录新浪财经APP 搜索【信披】查看更多考评等级 证券代码：300016 证券简称：北陆药业 公告编号：2025-094 一、重要提示 本半年度报告摘要来自半年度报告全文，为全面了解本公司的经营成果、财务状况及未来发展规划，投 资者应当到证监会指定媒体仔细阅读半年度报告全文。 所有董事均已出席了审议本报告的董事会会议。 非标准审计意见提示 □适用 √不适用 董事会审议的报告期利润分配预案或公积金转增股本预案 3、公司股东数量及持股情况 单位：股 ■ 持股5%以上股东、前10名股东及前10名无限售流通股股东参与转融通业务出借股份情况 □适用 √不适用 公司计划不派发现金红利，不送红股，不以公积金转增股本。 董事会决议通过的本报告期优先股利润分配预案 □适用 √不适用 公司是否需追溯调整或重述以前年度会计数据 □是 √否 ■ □适用 √不适用 前10名股东及前10名无限售流通股股东因转融通出借/归还原因导致较上期发生变化 □适用 √不适用 公司是否具有表决权差异安排 □是 √否 二、公司基本情况 1、公司简介 ■ 2、主要会计数据和财务指标 4、控股股东或实际控制人变更情况 控股股东报告期内变更 □适用 √不适用 ...

Group 1: Contrast Agent Product Strategy - The company has successfully integrated multiple contrast agent products into the national drug centralized procurement system, leading to significant changes in the competitive landscape and sales model of the industry, creating both challenges and opportunities [1] - The company has overcome challenges posed by price reductions in iodine contrast agents and is experiencing a recovery trend, with a focus on expanding market share for iodinated contrast agents [1] - The company has diversified its gadolinium-based contrast agents, with the approval of Gadobutrol injection in July 2024, enhancing its product offerings to meet various clinical needs [1] - In 2024, the contrast agent products achieved sales revenue of CNY 58,804.95 million, representing a year-on-year growth of 9.87% [2] Group 2: Jinlianhua Granule Procurement Progress - Jinlianhua Granule, a core product of Tianyuan Pharmaceutical, is a natural single-component preparation with applications in treating upper respiratory infections and is covered by national insurance [3] - The product is a unique offering in the market and has been included in procurement lists across multiple provinces, enhancing its market presence [3] Group 3: Medical Technology Focus - The company's subsidiary, Shenzhen Yiwei Medical Technology Co., Ltd., specializes in brain disease early screening, precise diagnosis, and rehabilitation training, making it a leader in the field of brain science AI [4] - Yiwei Medical's core products target stroke, Alzheimer's disease, cognitive disorders, and developmental disorders in youth, providing a comprehensive solution for brain disease management [4] Group 4: Yiwei Medical's Business Model - Yiwei Medical offers a full-service model from screening to rehabilitation for brain diseases, creating a closed-loop medical service system [6] - The company collaborates with health check institutions to provide a comprehensive "brain routine" health check package and has developed a unique diagnostic platform for neurodegenerative diseases [6] - Yiwei Medical is exploring additional business models to expand market coverage and increase revenue streams [6] Group 5: Zhiyou Medical Progress - Zhiyou Medical has received NMPA approval for its BCR/ABL and AML1/ETO fusion gene testing kits, marking a significant milestone in the field of blood cancer molecular diagnostics [7] - The approval solidifies Zhiyou Medical's position in the precision diagnosis of blood cancers and complements its existing product offerings for solid tumors [7][8] - The company has obtained nearly 200 NMPA certifications, covering various disease areas and advancing the FISH technology from high-end testing to clinical application [8]

Financial Performance - In Q1 2025, Beilu Pharmaceutical achieved operating revenue of 28,268.07 million yuan, a year-on-year increase of 36.23% [2] - The net profit attributable to shareholders increased by 26.13%, amounting to 1,308.80 million yuan, while the net profit excluding non-recurring gains and losses rose by 14.34% [2] Business Growth Drivers - The growth in Q1 2025 was primarily driven by three core segments: chemical generic drugs, traditional Chinese medicine, and overseas markets [3] - The acquisition of Tianyuan Pharmaceutical has led to significant integration efforts, enhancing marketing strategies and operational efficiency [3] Market Expansion - The company plans to leverage EU and Brazil GMP certifications to accelerate market development in these regions, aiming to enhance international brand influence and market share [4][5] - In Q1 2025, the subsidiary Haichang Pharmaceutical's iodinated contrast agent received approval for sale in South Korea, and the iodinated injection was approved in the EU [4] Financial Structure - The debt ratio reached 42.49% in Q1 2025, an increase attributed to a new long-term loan of 160 million yuan for acquiring 80% of Tianyuan Pharmaceutical [4] - Future plans include optimizing the capital structure and reducing the debt ratio through diversified financing channels [4] Subsidiary Developments - The company has established several wholly-owned subsidiaries, including: - Beijing Aipai Kesi Pharmaceutical R&D Co., focusing on product development and technological upgrades [5] - Anhui Luying Pharmaceutical Co., assisting in operations at the Bozhou production base [5] - Hong Kong Yuan Zhi Pharmaceutical Co., serving as an overseas window for market expansion [5] Product and Market Strategy - The company is actively promoting the Jiuwei Zhenxin Granules to enhance market share, despite stable procurement prices for key ingredients [5] - The company has not yet entered the veterinary medicine sector, focusing instead on prescription drugs [7]

Group 1: Financial Performance - The company's revenue for 2024 reached 98,355.45 million, a year-on-year increase of 10.42% [2] - Net profit attributable to shareholders was 1,365.17 million, up 119.02% year-on-year, with the parent company's net profit at 5,635.84 million, increasing by 838.39% [2] - In Q1 2025, revenue was 28,268.07 million, showing a growth of 36.23% year-on-year, while net profit rose to 1,453.85 million, up 26.13% [2] Group 2: Profitability and Margins - The gross margin for 2024 was 47.67%, an increase of 0.66 percentage points compared to 2023 [3] - The company plans to enhance gross margins through continuous improvement in production processes and cost reduction [3] Group 3: Product Performance - Sales revenue from contrast agents reached 58,804.95 million in 2024, a growth of 9.87% year-on-year [3] - Sales of antidiabetic products grew by 33.24% year-on-year, attributed to successful bidding and subsequent contracts [4] Group 4: Research and Development - R&D expenses for 2024 were 6,923.81 million, a decrease of 43.40% compared to the previous year, due to a more stable phase in R&D and improved efficiency [5] - The company has 12 projects under review and 23 new R&D projects initiated [5] Group 5: Subsidiary Developments - The acquisition of Tianyuan Pharmaceutical increased the number of traditional Chinese medicine products to 59, with a focus on promoting unique products [8] - The construction of the production base for Luzhibao Pharmaceutical is ongoing, with trial production expected to start within the year [7] Group 6: Investor Relations and Governance - The total number of shareholders decreased by 7.37% by the end of Q1 2025, indicating a shift towards attracting more quality investors [10] - The company emphasizes a stable and scientific dividend policy to ensure sustainable returns to shareholders [10] Group 7: Debt Management - The company has sufficient funds to repay the principal and interest of convertible bonds due next year, ensuring no repayment risk [11]

Group 1: Financial Performance - The company achieved a turnaround in 2024, primarily due to product structure optimization and increased marketing efforts, leading to stable revenue growth in the chemical drug sector [1] - The acquisition of 80% of Tianyuan Pharmaceutical contributed to revenue growth in the traditional Chinese medicine segment [1] - The company managed to reduce R&D investment compared to 2023 while maintaining a high level of overall R&D input [1][2] Group 2: R&D Strategy - In 2025, the R&D focus will be on chemical drugs, traditional Chinese medicine, and the health sector, aiming for technological innovation and market expansion [3] - The company received approval for "Silicone Oil Emulsion" and "Compound Polyethylene Glycol Electrolyte Powder (III)" in February 2025, enhancing its product pipeline in the digestive system field [3] - A strategic partnership with Anhui Chengqing Tang National Medicine Co., Ltd. aims to modernize traditional Chinese medicine production [3] Group 3: Subsidiary Operations - Shenzhen Yiwei Medical Technology Co., Ltd., a subsidiary, specializes in early screening, precise diagnosis, and rehabilitation for brain diseases, recognized as a national "little giant" enterprise [4] - Yiwei Medical's core products address stroke, Alzheimer's disease, cognitive disorders, and developmental disabilities, providing comprehensive solutions in the brain disease sector [5] Group 4: Business Model - Yiwei Medical offers a full-service model from screening to rehabilitation, creating a closed-loop medical service system [6] - The company collaborates with health check institutions to provide a comprehensive "brain routine" health check package [6] Group 5: International Expansion - The company has made significant progress in overseas markets, achieving full product line sales of contrast agents and obtaining EU GMP and Brazil ANVISA GMP certifications for its production line [7][8] - The company is accelerating the registration of contrast agent products for international markets, laying the groundwork for broader market expansion [8] Group 6: Acquisition Strategy - Recent acquisitions, such as Haichang Pharmaceutical and Tianyuan Pharmaceutical, have strengthened the company's competitive position in the contrast agent and traditional Chinese medicine markets [9] - Future acquisitions will align with the company's overall strategic development and business growth needs, adhering to regulatory requirements [9]