Core Insights - The article discusses the development of a 3D micro-nano robot by the Institute of Physics and Chemistry, Chinese Academy of Sciences, which can perform precise tasks in the microscopic world, paving the way for future advancements in precision medicine [1][7]. Group 1: Micro-Nano Robot Overview - Micro-nano robots are intelligent miniature machines that operate at the micro to nano scale, capable of movement, rotation, and manipulation of tiny particles or cells, thus enabling human interaction in the microscopic realm [2]. - The new design overcomes limitations of existing micro-nano robots, which often use single material systems and struggle with multi-step operations in complex environments [2][5]. Group 2: Design and Functionality - The micro-nano robot features a hand-like design that allows for flexible observation and manipulation of target particles, enhancing its operational capabilities [2]. - It is constructed using femtosecond laser direct writing technology, which allows for high-precision fabrication of various micro-nano structures with different functionalities [5]. Group 3: Operational Mechanism - The robot operates by responding to changes in pH levels in its environment, with its "hands" opening and closing like a flower in response to acidic or alkaline conditions [6]. - It can transport and release particles or cells with a maximum speed of 65.56 micrometers per second, demonstrating agility in navigating obstacles [6]. Group 4: Potential Applications - The micro-nano robot has significant potential in precision medicine, such as drug delivery and cellular manipulation, and could serve as an invisible assistant to doctors [7]. - Beyond medical applications, it can also be utilized in environmental remediation and micro-manufacturing, such as removing specific pollutants from water environments [7].

人民日报海外版记者 周姝芸 在显微镜下，一滴水可以奇妙得像一个城市。最近，这个微观"城市"里迎来了一名"快递员"——中 国科学院理化技术研究所最新研发的3D微纳机器人。它的尺寸仅为40微米左右，比头发丝的直径还要 小，却能像机械手一样完成抓取、运输和释放颗粒、细胞的精密任务，在微观世界实现"手到擒来"，为 未来精准医疗开辟了新路径。 "我们的出发点，是想要克服当前微纳机器人的局限。"中国科学院理化技术研究所仿生智能界面科 学中心研究员郑美玲介绍，目前微纳机器人多采用单一材料体系，功能难以扩展，在复杂环境中，要实 现多刺激协同控制、完成多步操作，是科研界面临的挑战。 基于此，团队提出了一个新思路：采用多材料多模块加工微纳机器人。 谈到为什么选择"手"的造型，郑美玲说："生活里，我们常用手抓取物体，所以在设计时，首先想 到了仿手型的微纳机器人。不仅如此，这只微型'手'采取双手向上托举的姿态，手掌部分能够灵活开 合。相比于封闭的结构，手指的开放造型更便于观察目标颗粒，也能在释放时更加灵活。" 如何做出这么精巧的"手"？科研人员表示，依靠的是"微观画笔"——飞秒激光直写技术。 微观"托举"的灵感 微纳机器人是什么？它 ...

Core Viewpoint - The article discusses the development of a 3D micro-nano robot by the Institute of Physics, Chinese Academy of Sciences, which can perform precise tasks in the microscopic world, paving the way for advancements in precision medicine [1][2]. Group 1: Micro-Nano Robot Overview - Micro-nano robots are intelligent miniature machines that can perform tasks such as movement, rotation, and the manipulation of small particles or cells, offering significant potential in fields like precision medicine, environmental remediation, and micro-manufacturing [2]. - The new design overcomes limitations of existing micro-nano robots, which often use single material systems and struggle with multi-stimulus control in complex environments [2][5]. Group 2: Design and Functionality - The robot is designed in the shape of a hand, allowing for flexible observation and manipulation of target particles, with a structure that opens and closes to enhance functionality [2][5]. - It utilizes femtosecond laser direct writing technology to create various micro-nano structures from different materials, enabling each part to have distinct functions [5]. Group 3: Operational Mechanism - The robot operates by responding to changes in pH levels in its environment, allowing its "hand" to open or close automatically, similar to a human hand reacting to heat [6]. - It can navigate around obstacles and accurately locate target particles or cells, successfully performing tasks such as grabbing and releasing under specific environmental conditions [6]. Group 4: Performance and Reliability - Experimental results show that the robot can successfully manipulate polystyrene microspheres and human kidney cancer cells, achieving a maximum speed of 65.56 micrometers per second while maintaining reliable performance after multiple cycles of pH changes [6][7]. - The robot's design addresses the limitations of traditional micro-nano robots, enabling more complex operations in the microscopic realm [7]. Group 5: Future Applications - The micro-nano robot has potential applications in medicine, such as targeted drug delivery and minimally invasive surgeries, as well as in environmental cleanup and micro-manufacturing [7]. - It could serve as a micro-operation platform for cell sorting, injection, and mechanical studies, contributing to advancements in both medical and scientific research [7].