国泰海通证券股份有限公司 关于 上海奥浦迈生物科技股份有限公司 本次交易产业政策和交易类型 国泰海通证券股份有限公司（以下简称"独立财务顾问"）作为上海奥浦迈 生物科技股份有限公司（以下简称"上市公司"）发行股份及支付现金购买澎立 生物医药技术（上海）股份有限公司（以下简称"澎立生物"或"标的公司"） 资金（以下简称"本次募集配套资金"，与本次发行股份及支付现金购买资产合 称"本次交易"）的独立财务顾问，根据中国证券监督管理委员会（以下简称"中 国证监会"）颁发的《监管规则适用指引—上市类第 1 号》等规范性文件的要求， 对上市公司本次交易产业政策和交易类型相关事项进行核查，现发表如下意见： 一、本次交易涉及的行业或企业是否属于《监管规则适用指引——上市类 第 1 号》确定的"汽车、钢铁、水泥、船舶、电解铝、稀土、电子信息、医药、 农业产业化龙头企业、高档数控机床和机器人、航空航天装备、海洋工程装备 及高技术船舶、先进轨道交通装备、电力装备、新一代信息技术、新材料、环 保、新能源、生物产业；党中央、国务院要求的其他亟需加快整合、转型升级 的产业 经核查，独立财务顾问认为：根据《国民经济行业分类与代码》 （GB ...

Group 1: Financial Performance - In Q1 2025, the company reported a revenue of 1.541 billion, representing a year-on-year growth of 10.1% [3] - The net profit attributable to shareholders was 327 million, with a year-on-year increase of 15.8% [3] - The net profit excluding non-recurring gains and losses grew by 20% year-on-year [3] Group 2: Business Segments - The small molecule CDMO business revenue remained flat, with a gross margin of 45.2% [3] - Emerging business revenue grew over 80% year-on-year, with a gross margin of 33.1% [3] - The company is focusing on expanding its capabilities in peptide, oligonucleotide, and ADC businesses [3] Group 3: Cost Management and Efficiency - The net profit growth outpaced revenue growth by 5.73 percentage points, indicating effective cost management [3] - The company is implementing cost reduction measures, resulting in a decrease in period expenses [3] - Capital expenditures will focus on emerging business areas, with limited new capital for small molecule capacity [3] Group 4: Market Outlook and Strategy - The company maintains a positive outlook for 2025, expecting double-digit revenue growth and net profit growth to exceed revenue growth [3] - There is confidence in achieving the revenue growth target based on current order coverage [4] - The company plans to enhance overseas capacity, particularly in Europe, to adapt to changing international circumstances [6] Group 5: Investor Engagement and Concerns - The company has engaged with over 240 participants from more than 100 institutions during the investor relations activity [2] - Concerns regarding the impact of the U.S. Biosecurity Act and tariff policies on business operations were addressed, indicating limited effects on competitiveness [4] - The company is actively managing supply chain challenges and maintaining communication with clients to ensure product delivery [4]