JAK/ROCK抑制剂罗伐昔替尼
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——海外消费周报(20260227-20260305):海外医药:中生与赛诺菲就JAK/ROCK抑制剂达成授权合作协议,信达生物BTK抑制剂国内获批新适应症-20260308
Shenwan Hongyuan Securities· 2026-03-08 11:30
海外消费服务 2026年03月08日 相关研究 劳研究知 证券分析师 黄哲 A0230513030001 huangzhe@swsresearch.com 周文远 A0230518110003 zhouwy@swsresearch.com 贾梦迪 A0230520010002 jiamd@swsresearch.com 册 分歧行 胡梦婷 A0230524060004 humt@swsresearch.com 联系人 胡梦婷 A0230524060004 humt@swsresearch.com 申万宏源研究微信服务号 海外医药:中生与赛诺菲就 JAK/ROCK 抑制剂达成授权 合作协议,信达生物 BTK 抑制剂国内获批新适应病 -海外消费周报(20260227-20260305) 本期投资提示: 海外医药:中生与赛诺菲就 JAK/ROCK 抑制剂达成授权合作协议,信达生物 BTK 抑制剂国 ● 内获批新适应症 业绩:晶泰控股:2025 年,公司预计实现收入不少于 7.8 亿元,同比增长至少约 193%; 净利润和归母净利润均不少于 1 亿元,同比祖亏为盈。和誉:2025 年,公司实现收入 6.12 亿元,同 ...
海外消费周报:中生与赛诺菲就JAK/ROCK抑制剂达成授权合作协议,信达生物BTK抑制剂国内获批新适应症-20260308
Shenwan Hongyuan Securities· 2026-03-08 10:08
Investment Rating - The report maintains an "Overweight" rating for the overseas pharmaceutical industry, indicating a positive outlook for the sector's performance compared to the overall market [5][10]. Core Insights - The report highlights significant developments in the pharmaceutical sector, including a licensing agreement between China National Pharmaceutical Group (Sinopharm) and Sanofi for the JAK/ROCK inhibitor, and the approval of a new indication for Innovent Biologics' BTK inhibitor in China [1][2]. - Performance forecasts for companies such as Crystal Holding and He Yu indicate substantial revenue growth, with Crystal Holding expected to achieve at least 780 million RMB in revenue for 2025, representing a year-on-year increase of approximately 193% [6][7]. Summary by Sections 1. Overseas Pharmaceuticals - Sinopharm and Sanofi have entered into an exclusive licensing agreement for the global development, production, and commercialization of the JAK/ROCK inhibitor, with potential milestone payments totaling up to 1.395 billion USD [2][7]. - Innovent Biologics' BTK inhibitor, Jiepalit (Pirtobrutinib), has received NMPA approval for a new indication in adult patients with chronic lymphocytic leukemia (CLL) who have previously undergone systemic treatment [2][7]. - Roche's BTK inhibitor Fenebrutinib has successfully met primary endpoints in a Phase III trial for relapsing multiple sclerosis, potentially becoming the first effective oral treatment for both relapsing and primary progressive forms of the disease [3][8]. 2. Performance Updates - Crystal Holding anticipates a revenue of no less than 780 million RMB in 2025, with a net profit of at least 100 million RMB, marking a turnaround from losses [6][7]. - He Yu expects to achieve 612 million RMB in revenue for 2025, reflecting a 21% year-on-year growth, with net profit projected at 55 million RMB, a 95% increase [6][7]. 3. Investment Recommendations - The report suggests focusing on innovative pharmaceutical companies with active commercialization and business development opportunities, including companies like BeiGene, Innovent Biologics, and others [10]. - It also highlights the importance of monitoring clinical progress in key pipelines for companies transitioning towards innovation [10].