自愿披露关于 JT118 获得药物临床试验 批准通知书的公告 证券代码：688180 证券简称：君实生物 公告编号：临 2025-044 上海君实生物医药科技股份有限公司 研究院、北京航空航天大学达成合作，共同开发猴痘重组蛋白疫苗。截至本公告 披露日，国内尚无预防猴痘病毒感染疫苗获批上市。 近日，上海君实生物医药科技股份有限公司（以下简称"公司"）控股子公 司上海君拓生物医药科技有限公司收到国家药品监督管理局核准签发的《药物临 床试验批准通知书》，JT118 注射液（项目代号"JT118"）的临床试验申请获 得批准。由于药品的研发周期长、审批环节多，容易受到一些不确定性因素的影 响，敬请广大投资者谨慎决策，注意防范投资风险。现将相关情况公告如下： 一、药品基本情况 药品名称：JT118 注射液 申请事项：境内生产药品注册临床试验 受理号：CXSL2500478 申请人：上海君拓生物医药科技有限公司 审批结论：根据《中华人民共和国药品管理法》《中华人民共和国疫苗管理 法》及有关规定，经审查，2025 年 6 月 11 日受理的 JT118 注射液符合药品注册 的有关要求，同意开展用于预防猴痘病毒感染的临床试验。 ...

君实生物公告，控股子公司上海君拓生物医药科技有限公司收到国家药品监督管理局核准签发的《药物 临床试验批准通知书》，JT118 注射液（项目代号"JT118"）的临床试验申请获得批准。JT118 是由猴痘 病毒抗原 A35 和 M1 串联融合组成的"二合一"重组蛋白疫苗，拟主要用于预防猴痘病毒感染。 ...

Market Overview - The Hang Seng Index is constrained by the March high of 24,874 points, with expectations of new financial policies from mainland China to stabilize the market, including reserve requirement ratio cuts and interest rate reductions [2] - The recent US-China trade negotiations have led to a temporary reduction in tariffs, with US tariffs on Chinese imports dropping from 145% to 30%, and Chinese tariffs on US goods decreasing from 125% to 10% for a 90-day period [2][3] - The Hang Seng Index's valuation has returned to reasonable levels, requiring significant positive developments in trade agreements and corporate earnings improvements to maintain upward momentum [2] Sector Focus - The report highlights a positive outlook for sectors such as financial stocks, automotive parts, and gold mining stocks, driven by recent developments in trade agreements and geopolitical factors [7][8] - The automotive sector in mainland China saw a year-on-year sales increase of 11.2% in May, with new energy vehicle sales rising by 36.9% [9] Company News - Horizon Robotics plans to raise approximately HKD 47 billion through a share placement at a discount of nearly 7% [10] - Kintor Pharmaceutical is preparing for an IPO in Hong Kong, aiming to raise around USD 100 million [10] - Pop Mart has expanded its production capacity but still faces supply shortages due to high demand for its products [11] - JD Logistics is expanding its operations in Saudi Arabia, having recruited over a thousand staff for its logistics services [10] - Alibaba is focusing on re-establishing its leadership in the technology sector, emphasizing AI and cloud infrastructure as key strategic pillars [10] Economic Indicators - The US Consumer Price Index (CPI) for May showed a year-on-year increase of 2.4%, with core CPI rising by 0.1% month-on-month, indicating that tariffs have not yet significantly impacted overall inflation levels [8] - The Federal Reserve is expected to maintain interest rates, with projections indicating two rate cuts totaling 0.5% for the year [4][8]