Core Viewpoint - The company has entered into a licensing and transfer agreement with Excalipoint for its proprietary T-cell connector TOPAbody platform, which includes two preclinical assets, aiming to enhance its global strategic positioning and focus on next-generation ADC drugs and immuno-oncology bispecific/trispecific antibodies [1][2]. Group 1 - The company will receive a total upfront payment of $10 million and up to $847.5 million in milestone payments related to research and commercialization [1][2]. - Excalipoint will gain exclusive global rights to develop and commercialize the target products under the agreement [1]. - The company has the right to appoint a director to Excalipoint's board, indicating a strategic partnership [2]. Group 2 - Excalipoint is set to conduct a Series A financing round, raising a total of $41 million from various investors, including Sequoia China and Yuan Sheng Venture Capital [2]. - The successful licensing transaction and financing are expected to unlock the commercial value of the company's existing product pipeline and technology [2]. - The transaction aligns with the company's strategy to accelerate the commercialization of late-stage products [2].

Group 1 - The company, Lepu Biopharma-B (02157), has announced a licensing and transfer agreement with Excalipoint for the proprietary T-cell connector TOPAbody platform, involving two preclinical assets [1] - Excalipoint will receive exclusive global rights to develop and commercialize target products, with the company receiving an upfront cash payment of $10 million, equity in Excalipoint, milestone payments up to $847.5 million, and royalties based on sales [2] - The board believes that this licensing deal and Excalipoint's A-round financing will enhance the commercial value of the company's existing product pipeline and technology, supporting its global strategic layout [3] Group 2 - The successful completion of the licensing transaction and A-round financing will allow the company to focus on advancing next-generation ADC drugs and immuno-oncology bispecific/trispecific antibodies, accelerating the commercialization of late-stage products [3]