北京和上海活动报名： 第三届全球手术机器人大会 2025医疗器械研发创新论坛 2025年8月25日，医疗器械公司 ProVerum 宣布完成 8000万美元（约合人民币5.7亿）B轮股权融资 。本轮由 MVM Partners 领投，OrbiMed 与爱尔兰战略投资 基金（ISIF）新加入，既有投资方 Gilde Healthcare、Lightstone Ventures、Atlantic Bridge 与 Enterprise Ireland 全部跟投。融资完成后，MVM合伙人 Hugo Harrod 与 OrbiMed合伙人 Dina Chaya 将加入公司董事会。 对一家仍处于产品商业化前夜的公司来说，这样的融资阵容和金额并不常见。更关键的是，资金将直接投入到 ProVee 系统的临床推进与商业化准备 之中。这枚由 镍钛合金制成的"前列腺扩张支架"，被ProVerum寄予厚望：它要成为 良性前列腺增生（BPH） 患者介于药物与手术之间的全新选择。 从资本的角度看，这是一次典型的"背书式"融资：顶级机构的进入，意味着它们不仅认可 ProVee 的技术潜力，也看好它在泌尿介入赛道的商业机会。从公司自身 来 ...

Financial Data and Key Metrics Changes - Second quarter revenues were $780.9 million, an increase of 4.2% year over year on a GAAP basis and up 1% on an adjusted constant currency basis [5][6] - Adjusted earnings per share were $3.73, a 9.1% increase year over year [6][25] - Adjusted gross margin was 59.7%, a 110 basis point decrease year over year, primarily due to cost inflation and unfavorable product mix [24] - Adjusted operating margin was 26.9%, a 20 basis point year over year increase [24] Business Line Data and Key Metrics Changes - Vascular Access revenue increased 1.4% year over year to $185.5 million, driven by growth in PICCs [9] - Interventional revenue was $170 million, an increase of 19.3% year over year, led by intra aortic balloon pumps and complex catheters [9] - Anesthesia revenues decreased 7.6% year over year to $96.4 million, impacted by tough comps in military orders [10] - Surgical business revenue increased 1.4% year over year to $114 million, with solid underlying trends [10] - Interventional Urology revenue decreased 8.3% year over year to $76.4 million, with pressure on UroLift [11] Market Data and Key Metrics Changes - Americas revenues were $525.7 million, a 2% increase year over year [7] - EMEA revenues decreased 2.1% year over year to $166.2 million, with strength in Interventional business offset by Anesthesia challenges [7] - Asia revenues were $89 million, a 1.2% increase year over year, driven by Southeast Asia, India, and Japan [8] Company Strategy and Development Direction - The company is progressing with the separation announced in February, aiming for focused strategic direction and streamlined operations [12][13] - A potential sale of NewCo is being pursued, with significant interest from potential buyers [13] - The acquisition of BioTronic's vascular intervention business is expected to enhance growth and improve margins, with anticipated annual revenues exceeding $800 million [16] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in operational excellence and value creation, with updated financial guidance reflecting strong performance [5][28] - The company expects total constant currency growth for 2025 to be in the range of 7.7% to 8.7% [28] - Management highlighted the positive impact of proposed CMS reimbursement changes on UroLift and Barajel, which could enhance growth prospects [72][73] Other Important Information - The company completed the acquisition of BioTronic for a net initial cash payment of €4 million [15] - The impact from tariffs is now estimated at approximately $29 million for 2025, a reduction from previous estimates [30] - The company plans to initiate a U.S. pivotal study for PRESOLVE technology in the coming months [19] Q&A Session Summary Question: Can you provide more context on the guidance bridge between tariffs, FX, and business outperformance? - Management expects organic growth of the BioTronic business in the second half of the year to be mid single digits, with a long-term growth expectation of 6% or better starting in 2026 [40][41] Question: Can you provide a rough breakout between the growth of remainco and newco? - Remainco is expected to grow in the upper 5% range, while newco's growth is anticipated to be in the mid single digits [45] Question: What is the outlook for the interventional business growth? - The interventional business is expected to grow high single to low double digits for the full year of 2025 [46] Question: Can you provide an update on the timing for the sale versus spin of NewCo? - If a spin proceeds, it is expected to occur in mid-2026, while the timing for a sale remains uncertain [50][81] Question: How will the proposed CMS rule impact UroLift? - The proposed rule is expected to provide a 10% uplift in reimbursement, which could significantly benefit UroLift's growth [72][84] Question: What is the site of service mix for Barajel? - The site of service mix for Barajel is spread across all three service sites, with the proposed uplift expected to encourage more product movement to the office side [87]

Financial Data and Key Metrics Changes - Second quarter revenues were $780.9 million, an increase of 4.2% year over year on a GAAP basis and up 1% on an adjusted constant currency basis, exceeding previous guidance of $769 million to $777 million [5][6] - Adjusted earnings per share were $3.73, a 9.1% increase year over year [6][25] - Adjusted gross margin was 59.7%, a decrease of 110 basis points year over year, primarily due to cost inflation and unfavorable product mix [23][24] - Adjusted operating margin was 26.9%, a 20 basis point year over year increase [23][24] Business Line Data and Key Metrics Changes - Americas revenues were $525.7 million, a 2% increase year over year, driven by intra-aortic balloon pumps [7] - EMEA revenues decreased 2.1% year over year to $166.2 million, with strength in Interventional business offset by challenges in Anesthesia [7] - Asia revenues were $89 million, a 1.2% increase year over year, driven by Southeast Asia, India, and Japan [8] - Vascular Access revenue increased 1.4% year over year to $185.5 million, led by growth in PICCs [9] - Interventional revenue was $170 million, a 19.3% increase year over year, driven by intra-aortic balloon pumps and complex catheters [9] - Anesthesia revenues decreased 7.6% year over year to $96.4 million, primarily due to tough comps in military orders [10] - Surgical business revenue increased 1.4% year over year to $114 million, with solid underlying trends [10] Market Data and Key Metrics Changes - The company expects continued revenue improvement in China through the remainder of 2025, despite previously announced volume-based procurement dynamics [8] - The acquisition of the Vascular Intervention business is expected to generate over $800 million in annual revenues [15] Company Strategy and Development Direction - The company is progressing with the separation announced in February, aiming for focused strategic direction and streamlined operations [12][36] - A potential sale of NewCo is being pursued, with significant interest from potential buyers [13][36] - The acquisition of BioTronic's vascular intervention business is a key part of the value creation strategy, expected to enhance global presence and improve patient care [15][16] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about operational excellence and value creation, with updated financial guidance reflecting strong performance [5][36] - The company anticipates total constant currency growth for 2025 to be in the range of 7.7% to 8.7%, significantly higher than previous guidance [27][28] - Management highlighted the positive impact of proposed reimbursement changes from CMS on UroLift and Baragel, which could enhance growth prospects [71][72] Other Important Information - Cash flow from operations for the first half of 2025 was $81.2 million, a decrease from $204.5 million in the prior period, primarily due to unfavorable changes in working capital [26] - The company expects a tariff impact of approximately $29 million in 2025, a reduction from previous estimates [30] Q&A Session Summary Question: Can you provide more context on the guidance bridge between tariffs, FX, and business outperformance? - Management indicated that the organic growth expectation for the Biotronic business is mid-single digits for the second half of the year, with overall operational performance contributing positively to EPS [40][41] Question: What is the growth outlook for remainco and newco? - Remainco is expected to grow in the upper 5% range, while newco's interventional business is anticipated to grow high single to low double digits for the full year of 2025 [44][46] Question: Can you discuss the timing and decision-making process for NewCo? - The timing for a potential spin-off is still mid-2026, with ongoing due diligence and interest from potential buyers [50][81] Question: How will the proposed CMS rule impact UroLift? - The proposed rule is expected to provide a 10% uplift in reimbursement for UroLift, which could significantly enhance growth prospects [71][84] Question: What are the expectations for the integration of the BioTronic salesforce? - The integration is expected to leverage existing channels, with significant opportunities for revenue synergies due to the combined sales force [94][95]

Summary of Teleflex Conference Call Company Overview - **Company**: Teleflex - **Industry**: Medical Technology Q1 Results - **Growth Performance**: Q1 growth was reported at -3.8%, adjusted for two less selling days, the growth was approximately -1.7% [3][4] - **Product Performance**: Strong performance noted in balloon pumps in The Americas and progress with Pallet and Baragel products [3][4] - **OEM Challenges**: OEM segment experienced negative growth due to a lost customer costing approximately $7 million and inventory management issues among key customers [5][6] Guidance and Growth Expectations - **Full Year Guidance**: Reiterated guidance of 1% to 2% growth for the year, with expectations of acceleration in the second half [7][10] - **Quarterly Projections**: Anticipated growth of 1% in Q2, 3.5% in Q3, and 6% in Q4, with a significant pickup expected due to the anniversary of the lost customer and additional selling days in Q4 [7][8][10] Tariff Impact - **Tariff Guidance**: Total tariff impact estimated at $55 million, with 50% attributed to China. The company is hopeful for exemptions for medical devices [11][13][15] - **Mitigation Strategies**: Strategies include improving USMCA compliance, pricing adjustments, and supply chain changes to mitigate tariff impacts [20][21] Business Separation Strategy - **Separation Rationale**: Decision to separate into two entities based on different capital allocation and growth strategies, aiming to unlock shareholder value [25][26] - **Growth Profiles**: One entity expected to grow at low single digits with mid-fifties gross margins, while Teleflex RemainCo projected to grow at over 6% with mid-sixties gross margins [27][28] Market Dynamics - **OEM Business Outlook**: Anticipated negative growth of 10-12% for the OEM segment in 2025, but expected to return to growth in 2026 [35][36] - **UroLift Challenges**: UroLift has faced pressure due to reimbursement changes, but improvements are expected as the reimbursement environment stabilizes [37][38] Acquisition Interest - **Interest in NewCo**: Significant inbound interest in NewCo assets from both financial and strategic parties, indicating strong market validation [41][42] - **Sale vs. Spin**: The decision on whether to sell or spin off NewCo will be based on what maximizes shareholder value [43][46] Product Performance Highlights - **Pallet Growth**: Pallet product grew approximately 30% in the previous year and continues to trend above initial growth expectations [59][60] - **Baragel Market Expansion**: Anticipated market expansion for Baragel with a new indication for post-radical prostatectomy spacing expected by the end of 2026, potentially adding $100 million to the addressable market [61][63][64] Conclusion - Teleflex is navigating a challenging environment with strategic adjustments in response to market dynamics, tariff impacts, and a focus on unlocking shareholder value through business separation and product innovation.