For purposes of this notice, the "presentation" that follows shall mean and include the slides that follow, any oral presentation of the slides by members of management of Immunome, Inc. ("Immunome") or any person on its behalf, any question-and-answer session that follows that oral presentation, hard copies of this document and any materials distributed at, or in connection with, that presentation. References to "we," "our," and "us" refers to Immunome and its subsidiaries. This presentation shall not cons ...

Immunome, Inc. (IMNM) shares rallied 6% in the last trading session to close at $9.3. This move can be attributable to notable volume with a higher number of shares being traded than in a typical session. This compares to the stock's 0.1% gain over the past four weeks.The sudden price rise can be attributed to growing investor optimism regarding the company’s efforts to develop its lead pipeline candidate, varegacestat, which is currently in late-stage clinical studies for the treatment of desmoid tumors. I ...

2025年1月，Immunome完成1.5亿美元融资，此轮融资将推动核心管线的临床转化。3月，Immunome宣布靶向ROR1的ADC（抗体-偶联药物）IM-1021完 成I期临床试验首例患者给药。其核心产品管线Varegacestat（AL102）Ⅲ期RINGSIDE试验也已完成入组，预计2025年下半年公布顶线数据。 Immunome的核心竞争力是快速抗体筛选与精准递送技术。高效、精准且安全性高的治疗优势突破了传统癌症治疗中"脱靶损伤"与研发周期过长的行业瓶 颈。 这家临床阶段的靶向肿瘤学公司已累计融资5.989亿美元、21轮资本加持——成立17年的Immunome，凭什么让投资者持续买单？ 利用天然抗体解决脱靶损伤的精准性难题 传统化疗与放疗的局限性在于其作用机制缺乏特异性，药物或辐射在攻击癌细胞的同时会无差别损伤快速分裂的健康细胞（如骨髓、消化道细胞），导致 患者免疫力下降、脱发等严重副作用。这种攻击对人体健康组织损伤率高达60%。以胰腺癌为例，传统放疗虽能缩小肿瘤，但患者容易出现消化道溃疡等 严重并发症。 据塔夫茨药物开发研究中心数据，开发一款新药平均耗时10年、耗资26亿美元左右，且90%以上候选 ...