Group 1 - The establishment of the academician expert workstation at Deyizhi Pharmaceutical Co., Ltd. is approved by the Beijing Association for Science and Technology, marking a significant step in the company's innovation-driven development strategy [1] - The collaboration with Academician Yang Baofeng will focus on drug research and development in various fields, including cardiovascular diseases, tumors, metabolic system diseases, pulmonary hypertension, and neurological disorders [1][2] - Deyizhi Health is actively advancing several innovative drug projects, including neuroprotective agents, antithrombotic drugs, and cannabinoid-related medications [2] Group 2 - The partnership with Academician Yang Baofeng's team is expected to enhance the company's technological capabilities and innovation strategies, leading to the development of competitive new products and processes [2] - The approval of the academician expert workstation is seen as a crucial move to improve the company's research capabilities, attract high-end talent, and promote the transformation of research results [3] - The company aims to strengthen existing innovation platforms, enhance technological innovation capabilities, and accelerate the industrialization of research achievements to drive revenue growth and diversify its business structure [3]

Group 1: Research and Development - The company has 4 specialized pharmaceutical research institutions and 1 postdoctoral workstation, with a research team of approximately 200 people, accounting for about 20% of total employees. In 2024, R&D investment is expected to be 16.76% of sales revenue [1] - The WYY project is a novel compound with over 20 intellectual property applications globally, demonstrating superior efficacy and safety compared to competitors in animal studies. It is currently in the preclinical research stage, with an IND application planned for submission within the year [2] Group 2: Project Updates - The Wuhan Psychological Rehabilitation Hospital project received its medical institution practice license by the end of December 2024, aiming to operate as a tertiary specialized hospital [4] - The company is advancing the production line for recombinant collagen, with stable production processes meeting industry standards, and is preparing for large-scale production [6] Group 3: Market and Financial Insights - The gross profit margin for the company's main product, "A Le," has remained around 60% despite the impact of centralized procurement policies [8] - The company is considering external licensing for the WYY project based on clinical trial progress and commercialization conditions [3] Group 4: Future Developments - The company is focusing on developing CBD for treating pulmonary arterial hypertension, with a significant unmet market demand, as there are approximately 12 million patients in China [7][8] - VGX-3100, a key project of a major associate company, is undergoing phase III clinical trials for HPV-related cervical lesions, with plans to complete participant enrollment by 2025 [8]

Core Viewpoint - The company is in a transformation phase but is increasing R&D investment, with several innovative drugs making progress, which provides assurance for future revenue growth [1][2]. Financial Performance - In 2024, the company achieved revenue of 466 million yuan, with a net loss attributable to shareholders of 20.41 million yuan, resulting in a basic earnings per share of -0.0095 yuan [1]. - For Q1 2025, the company reported revenue of 89.28 million yuan and a net loss attributable to shareholders of 22.11 million yuan [1]. - The gross profit margin improved to 64.13% in 2024, an increase of 5.39 percentage points from the previous year, primarily due to significant reductions in labor and manufacturing costs [1]. - As of the end of 2024, total assets were 5.319 billion yuan, with total liabilities of 154 million yuan, mostly interest-free; equity attributable to shareholders was 5.158 billion yuan, and the debt-to-asset ratio remained low at 2.91% [1]. R&D Investment - The company increased R&D investment to 78.20 million yuan in 2024, a year-on-year growth of 53.05%, with R&D expenses accounting for 16.76% of revenue, up 6.50 percentage points from the previous year [1]. - In 2024, the company was granted 11 invention patents and filed 43 patent applications, indicating strong R&D activity [1]. Innovative Drug Projects - The WYY innovative drug project has completed laboratory research and is progressing in pharmacology and toxicology, with expectations to obtain clinical trial permits in both China and the U.S. by the end of 2025 [3]. - The company has initiated production line construction for the semaglutide project and completed pilot tests for recombinant human collagen [3]. - Progress has been made in CBD-related projects, including preclinical studies for a new drug for pulmonary arterial hypertension and the establishment of a pharmaceutical-grade CBD raw material workshop [3]. Other Key Projects - The company’s associate, Dongfang Lue Biotechnology, is advancing the VGX-3100 project, which is in Phase III clinical trials for treating cervical precancerous lesions caused by HPV [4]. - Other key projects are ongoing, including the ZT project, which is optimizing lead compounds, and a flavonoid compound project for pancreatic cancer [4]. Future Strategy - In 2025, the company plans to leverage industry policy benefits, strengthen existing product lines, enhance innovation capabilities, and promote the industrialization of research outcomes [5]. - The company aims to establish a new ecosystem in the pharmaceutical and health industry, focusing on a "pharmaceutical + medical + health" business model [5].