YL201(B7H3)
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前高管创业纠纷落幕:科伦博泰与宜联生物和解 共分产品收益
2 1 Shi Ji Jing Ji Bao Dao· 2025-12-18 23:15
Core Viewpoint - Kolonbo Tai has reached a settlement agreement with Yilian Bio and its key personnel to resolve previous disputes, aiming to save litigation time and costs [1] Group 1: Settlement Agreement - The settlement involves Yilian Bio sharing revenue and net profits from six products (YL201, YL202, YL211, YL212, YL221, YL222) with Kolonbo Tai [1] - Kolonbo Tai stated that the settlement aligns with the overall interests of the company and its shareholders, and will not significantly impact the group's financial status or operations [1] Group 2: Background of the Dispute - The dispute originated from Kolonbo Tai's criminal complaint against Yilian Bio in 2024 and subsequent civil lawsuits in 2025 regarding alleged commercial secret infringements [1][2] - Key executives of Yilian Bio, including its founder and CEO, have previous ties to Kolonbo Tai, which may have contributed to the disputes [2][3] Group 3: Product Development and Collaborations - Yilian Bio's product YL201 is in Phase III clinical trials and received breakthrough therapy designation from the FDA for small cell lung cancer [6] - The company has established significant collaborations, including a global partnership with Roche for YL211, which includes a $50 million upfront payment and potential milestone payments nearing $1 billion [6][7] - Yilian Bio has also engaged in multiple strategic collaborations with BioNTech and Zai Lab, indicating strong business development activity [7] Group 4: Market Context and Future Prospects - The rapid resolution of the dispute may be linked to Yilian Bio's plans for an IPO, as resolving intellectual property issues is crucial for the approval process [2][8] - The current hot market for Hong Kong IPOs suggests that Yilian Bio could aim for a 2026 listing, emphasizing the importance of business development capabilities and clinical progress [8]
科伦博泰与“前员工”和解,宜联生物付出6条ADC管线授权及销售分成
Mei Ri Jing Ji Xin Wen· 2025-12-17 09:15
Core Viewpoint - The long-standing dispute between Kolon Biotech (科伦博泰) and its former executive team has been resolved through a settlement agreement, which includes sharing future revenues from key ADC (antibody-drug conjugate) pipelines developed by Yilian Biopharma (宜联生物) [1][2]. Group 1: Dispute Background - The dispute began in 2020 when key executives left Kolon Biotech to establish Yilian Biopharma, escalating to criminal charges and civil lawsuits regarding "trade secret infringement" by 2024-2025 [1]. - The former executives involved include Xue Tongtong, who was the General Manager at Kolon Biotech, and other key figures who played significant roles in drug development and commercialization [3]. Group 2: Settlement Details - The settlement agreement stipulates that Yilian Biopharma will share a portion of the revenues and net profits from six core ADC pipelines with Kolon Biotech, which have been developed using the TMALIN platform [1][5]. - The specific ADC pipelines mentioned include YL201, YL202, YL211, YL212, YL221, and YL222, with YL201 currently in Phase III clinical trials for small cell lung cancer and nasopharyngeal carcinoma [5]. Group 3: Financial Implications - YL202 was licensed to BioNTech for a $70 million upfront payment, with potential total payments exceeding $1 billion [5]. - YL211's global exclusive rights were granted to Roche for an upfront payment of $50 million, along with nearly $1 billion in potential milestone payments based on future sales [6]. Group 4: Strategic Insights - The settlement reflects a significant shift in Yilian Biopharma's operational strategy, which has focused on an authorization model for survival, necessitating the sharing of revenue as a cost of resolving the dispute [7].