Icahn Enterprises L.P. Investor Presentation May 2025 Forward-Looking Statements and Non-GAAP Financial Measures Forward-Looking Statements This presentation contains certain statements that are, or may be deemed to be, "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. All statements included herein, other than statements that relate solely to historical fact, are "forward-looking stat ...

CF Industries Investor Day Summary Company Overview - CF Industries is the world's largest producer of ammonia, founded in 1946 as an agricultural cooperative [4][10] - The company focuses on ammonia and derived nitrogen products used as fertilizers and for industrial applications [4][5] Core Business Insights - CF Industries emphasizes operational excellence, safety, and unmatched asset utilization to meet customer needs [5][11] - The company aims to lead in low carbon ammonia production, contributing to decarbonization in industrial and agricultural sectors [5][7] Financial Performance - In the past year, CF reported approximately $2,500 million in adjusted EBITDA, converting to $1,600 million in free cash flow, a 63% conversion rate [97] - Over the last eight years, CF generated $19,000 million in adjusted EBITDA and over $12,000 million in free cash flow, with a leading conversion rate of over 62% [98] - The company returned approximately $2,000 million to shareholders in the last year through dividends and share repurchases [97] Strategic Initiatives - CF is investing roughly $2,000 million into the BluePoint joint venture, focusing on low carbon ammonia production [17] - The company has a concurrent share repurchase program for $2,600 million [17] - CF's recent acquisition of the Wagaman ammonia production facility in 2023 is part of its strategy to enhance production capacity [16] Market Dynamics - The global nitrogen supply-demand balance is expected to tighten, with projected annual demand growth of 12 to 14 million metric tons [54][55] - Structural constraints on nitrogen supply have been exacerbated by geopolitical events, leading to rising global nitrogen prices [49][51] - CF's North American operations provide a significant cost advantage due to access to low-cost natural gas [32][33] Competitive Advantages - CF's production network consists of approximately 60 production units across eight sites in North America, with an average annual capacity of about 10,500,000 metric tons of gross ammonia [36] - The company has unmatched distribution flexibility, utilizing rail, truck, barge, and ocean-going vessels to deliver products efficiently [41][42] - CF's operational excellence is reflected in its industry-leading utilization rates, averaging 8% greater than North American peers [73] Sustainability and Decarbonization - CF aims to reduce scope one carbon emissions intensity per product ton by 25% by 2030 [74] - The company is investing in carbon capture and sequestration projects, expecting to reduce greenhouse gas emissions by over 2,500,000 metric tons of CO2 equivalent annually [75] - CF's BluePoint project is positioned to be the world's largest ammonia plant focused on low carbon production, with a nameplate capacity of 1,400,000 tons annually [87] Future Outlook - The company anticipates significant long-term demand growth for low carbon ammonia, driven by government policies and market needs [59][60] - CF believes that the tightening nitrogen supply-demand balance will offer increased margin opportunities in the future [56] - The company is strategically positioned to capitalize on these trends, leveraging its operational expertise and partnerships [82][86]

Group 1 - CVR Partners, LP has made the 2024 Schedule K-3s available online for unitholders, which contain items of international tax relevance [1] - The Schedule K-3 is particularly relevant for foreign unitholders and those needing to compute a foreign tax credit [2] - CVR Partners will not mail Schedule K-3s to investors; unitholders can request an electronic copy via a dedicated support line [3] Group 2 - CVR Partners, LP is headquartered in Sugar Land, Texas, and focuses on the production, marketing, and distribution of nitrogen fertilizer products [4] - The company primarily produces urea ammonium nitrate (UAN) and ammonia, which are essential for improving crop yield and quality [4] - CVR Partners operates two nitrogen fertilizer manufacturing facilities, one in Coffeyville, Kansas, and another in East Dubuque, Illinois, with significant production capacities [4]

Core Viewpoint - Plug Power is positioning itself as a leader in the hydrogen economy, focusing on expanding its integrated ecosystem and securing significant projects to drive growth and profitability in the coming years [1][16]. Expansion of Hydrogen Economy - Plug Power has expanded its partnership with Allied Green Ammonia, securing a deal to supply 2 gigawatts (GWs) of proton exchange membrane (PEM) electrolyzers for a $5.5 billion sustainable fuels project in Uzbekistan [3][4]. - This project aims to produce sustainable aviation fuel, green urea, and green diesel, with government backing from Uzbekistan [3]. Project Developments - The collaboration with Allied Green continues from a previous commitment to supply 3 GWs of electrolyzers for a green ammonia facility in Australia [4]. - A final investment decision (FID) for the Australian project is expected in Q4 2023, later than the initial Q2 expectation, with manufacturing and delivery of PEM electrolyzers planned for 2027 [5]. Growth Targets - Plug Power is targeting a 30% compound annual growth rate in its energy business and applications business through 2030, driven by its electrolyzer and cryogenic solutions [7]. - The company anticipates 2025 to be a transformational year, aiming for a positive gross margin run rate and significant annual savings through its Project Quantum Leap [8]. Financial Challenges - The company has faced challenges in financing its operations, with net cash used in operating activities amounting to $728.6 million in 2022, $1.1 billion in 2023, and $828.6 million in the previous year [10]. - To fund operations, Plug Power has raised capital through issuing new stock, leading to a significant increase in outstanding shares and a decline in stock price by over 90% in the past three years [11][13]. Funding and Future Outlook - Plug Power has raised $280 million by selling over 185 million shares and secured a $525 million credit facility, along with a $1.66 billion loan guarantee from the U.S. Department of Energy [14]. - Despite these efforts, the company does not expect to reach profitability until 2028, raising concerns about potential future dilutive equity issuances [15].

Key Takeaways CF stock surged 20.8% in 3 months, outperforming the fertilizer industry. Strong nitrogen demand and rising prices are fueling CF's top-line growth. CF repurchased $434M in shares in Q1 and approved a new $2B buyback program through 2029.CF Industries Holdings, Inc.’s (CF) shares have gained 20.8% over the past three months. The company has also outperformed the Zacks Fertilizers industry’s 19.2% rise over the same time frame. CF has also topped the S&P 500’s roughly 4% increase over the sam ...

Core Viewpoint - CF Industries Holdings, Inc. has experienced a 15% increase in share price over the past month, outperforming both the Zacks Fertilizers industry and the S&P 500 index during the same period [1][3]. Group 1: Demand Factors - The rising global demand for nitrogen fertilizers is primarily driven by significant agricultural needs and recovering industrial demand post-pandemic [3]. - In North America, high levels of corn planted acres and low nitrogen channel inventories are expected to boost nitrogen demand [3]. - Brazil is anticipated to see strong urea demand due to increased corn plantings, while India is expected to experience low inventory levels, driving urea imports [5]. Group 2: Supply-Demand Balance - The global supply-demand balance for nitrogen fertilizers is expected to remain favorable due to low corn stocks-to-use ratios and challenging production conditions in Europe [4]. - CF Industries anticipates strong nitrogen demand during the spring application season, driven by favorable returns for corn compared to soybeans [5]. Group 3: Financial Performance - CF Industries reported a 13% year-over-year increase in net sales, reaching $1,663 million in the first quarter, attributed to higher nitrogen prices [6]. - The company’s net cash provided by operating activities increased by approximately 32% year-over-year to $586 million [8]. - CF Industries repurchased 5.4 million shares worth $434 million during the quarter and has a remaining $630 million in its current $3 billion share repurchase program, along with a newly authorized $2 billion program effective through 2029 [8].

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Fulcrum Therapeutics Inc (FULC) 2025 Conference Summary Company Overview - Fulcrum Therapeutics is a SMIDGAP biotech company focused on rare benign hematological conditions, with its lead program, Posiridir, targeting sickle cell disease currently in Phase 1b studies [4][2] Market Opportunity in Sickle Cell Disease - Sickle cell disease affects approximately 100,000 people in the U.S. and 4.4 million globally, with a significantly decreased life expectancy of 20 to 25 years [6][6] - Recent drug approvals have not met expectations; Voxelotor was pulled from the market, and Crizanlizumab failed to show significant efficacy in reducing vaso-occlusive crises [7][8] - The unmet need in the sickle cell market remains extremely high, creating an opportunity for Posiridir [8][8] Mechanism of Action - Posiridir induces fetal hemoglobin (HBF) expression, which can mitigate the effects of sickle hemoglobin by diluting it and preventing sickling under hypoxic conditions [10][12] - The drug works by inhibiting the PRC2 enzyme complex, leading to an altered gene expression profile that upregulates the HBG gene responsible for fetal hemoglobin production [11][12] Clinical Development and Regulatory Updates - A clinical hold was placed by the FDA in early 2023 due to preclinical findings of hematological malignancies, but the hold was lifted after redefining the patient population to include more severely affected patients [14][16][18] - The new inclusion criteria restrict concomitant use of hydroxyurea, which is labeled as a carcinogen, to ensure patient safety during early development [19][21] Patient Population and Enrollment - Approximately 10% of the 100,000 U.S. sickle cell patients meet the new inclusion criteria, equating to about 10,000 potential participants for the study [22][22] - The company anticipates that demonstrating the drug's efficacy in increasing fetal hemoglobin levels could lead to a relaxation of these criteria in future studies [24][24] Efficacy and Clinical Meaningfulness - There is a strong correlation between increased fetal hemoglobin levels and reduced vaso-occlusive crises, with a target of achieving a clinically meaningful reduction of at least 25% in these crises [29][30] - Initial cohorts showed dose-dependent increases in fetal hemoglobin, with higher doses leading to more significant increases [26][27] Competitive Landscape - Renewed interest in fetal hemoglobin as a treatment mechanism has emerged, with several competitors entering the field, including BMS, Novartis, and GSK, although they are at earlier stages of development compared to Fulcrum [33][34] Financial Position and Future Aspirations - Fulcrum has a cash position of approximately $226 million, with an annual burn rate of $55 to $65 million, providing a runway until at least 2027 [40][41] - The company aims to expand beyond sickle cell disease and become a leader in benign hematological rare conditions [41][42]

Core Viewpoint - CF Industries is positioned to benefit significantly from the recent reduction in tariffs between the US and China, which is expected to enhance farm profits and boost demand for fertilizers [3][4]. Group 1: Tariff Impact - The reduction of tariffs from 125% to 10% on US exports to China and from 145% to 30% on Chinese exports is favorable for CF Industries, as it creates a "Goldilocks" tariff zone that protects US suppliers while facilitating trade [4]. - CF Industries, being a major US fertilizer producer, stands to gain from improved profitability in American agriculture due to these tariff changes [4]. Group 2: Production and Cost Advantages - CF Industries operates six plants in the US, one in Canada, and one in the UK, allowing it to leverage cheaper North American natural gas, which constitutes 70% of ammonia production costs [5]. - The company is planning to increase its output in the US, indicating a proactive approach to meet rising demand [5]. Group 3: Strategic Initiatives - CF Industries is investing in a new $4 billion ammonia plant in Louisiana, which will incorporate advanced carbon capture technology, addressing the global ammonia shortage [10]. - The construction of the new plant is being executed through a joint venture with Japanese firms, which helps mitigate financial risk [11]. Group 4: Financial Performance and Shareholder Returns - CF Industries has returned $5 billion to shareholders through dividends and buybacks since 2022, with an additional $2 billion buyback authorization recently approved [13]. - The company's shares are currently trading at approximately 11.4 times trailing earnings, significantly lower than the S&P 500 average of around 23, indicating a potential undervaluation [12]. - The dividend yield stands at 2.3%, with expectations for future increases due to a reduced share count and a healthy balance sheet, which shows only $1.6 billion in long-term debt against $13.3 billion in assets [14].

Core Insights - Tenable has introduced significant enhancements to its flagship platform, Tenable One, including Tenable One Connectors and customizable risk dashboards, aimed at providing a comprehensive exposure management solution [1][6] - The platform addresses the challenges posed by the fragmented security landscape, where organizations typically manage an average of 83 disconnected tools, leading to operational inefficiencies and blind spots [2][6] - Tenable One integrates data from both native and third-party security tools, offering a unified view of organizational risk and enabling faster, smarter security decisions [3][4] Product Features - The new ecosystem of out-of-the-box Connectors allows seamless integration with various third-party tools, enhancing endpoint detection, cloud security, and vulnerability management [3] - The Tenable Exposure Data Fabric serves as the platform's scalable, cloud-native architecture, which normalizes and connects data across the security ecosystem [4] - Customizable risk dashboards are designed to streamline reporting processes, providing security teams with tailored insights that align with specific business roles and priorities [5] Market Context - The cybersecurity market is characterized by a saturation of point solutions that operate in isolation, which can hinder security efforts and leave organizations vulnerable [6] - Tenable's acquisition of Vulcan Cyber is highlighted as a strategic move to enhance its capabilities in the exposure management market, reinforcing its commitment to providing comprehensive security solutions [6][8]