证券代码：430047 证券简称：诺思兰德 公告编号：2025-042 北京诺思兰德生物技术股份有限公司证券事务代表任命公告 本公司及董事会全体成员保证公告内容的真实、准确和完整，没有虚假记载、误导 性陈述或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连带法律责任。 一、证券事务代表任命的基本情况 北京诺思兰德生物技术股份有限公司(以下简称"公司")于 2025 年 6 月 30 日召开 第六届董事会第十八次会议，审议通过了《关于聘任公司证券事务代表的议案》。 聘任李丽华女士为公司证券事务代表，任职期限至第六届董事会任期届满之日止， 自 2025 年 6 月 30 日起生效。该人员持有公司股份 117,373 股，占公司股本的 0.04%， 不是失信联合惩戒对象。 （上述人员简历详见附件） 二、合规性说明及影响 （一）人员变动的合规性说明 李丽华女士具备履行职责所必需的专业知识、工作经验及相关素质，能够胜任相关 岗位职责的要求，其任职资格符合《中华人民共和国公司法》《北京证券交易所股票上 市规则》等相关法律法规的规定。 本次聘任证券事务代表对公司生产、经营无重大影响。 三、备查文件 《北京诺思兰德 ...

Investment Rating - The report assigns a "Buy" rating for the company, marking the first coverage of the stock [7][8]. Core Insights - The company has made significant progress in clinical trials for its product NL003, which is now entering the commercialization phase [5]. - The company reported a revenue of 72.11 million yuan in 2024, reflecting a year-on-year growth of 20.8%, while the net profit attributable to shareholders was -45.18 million yuan, indicating a reduction in losses compared to the same period in 2023 [4]. - The company has a comprehensive pipeline of ophthalmic drugs, with eight registered eye drop products targeting various conditions such as dry eye, allergies, and bacterial infections [4]. Financial Projections - Revenue projections for 2025, 2026, and 2027 are estimated at 88 million yuan, 185 million yuan, and 371 million yuan, respectively, with corresponding growth rates of 21.7%, 110.8%, and 100.5% [10]. - The report forecasts a gradual improvement in net profit, with expected figures of -51 million yuan in 2025, -2 million yuan in 2026, and a positive 83 million yuan in 2027 [10]. - The earnings per share (EPS) are projected to be -0.19 yuan in 2025, -0.01 yuan in 2026, and 0.30 yuan in 2027, indicating a turnaround in profitability [10]. Clinical and Production Developments - The NL003 project has completed the unblinding of its Phase III clinical trials for both ulcer and resting pain groups, with results showing significant efficacy compared to the placebo group [5]. - The company is advancing its biopharmaceutical production facility in Beijing, which is expected to enhance its production capacity for innovative drugs [6].

Group 1: Company Overview - The company achieved a revenue of 72.11 million yuan in 2024, representing a year-on-year growth of 20.8%, while the net profit attributable to shareholders was -45.18 million yuan, a reduction in losses compared to the same period in 2023 [1] - In Q1 2025, the company reported a revenue of 16.42 million yuan, a year-on-year increase of 1.85%, with a net profit of -0.77 million yuan, marking a 37.01% reduction in losses compared to the previous year [1] - The company has not yet launched any new drugs, but its ophthalmic products are the core revenue source, continuously supporting new drug development [1] Group 2: Clinical Progress - The company's NL003 project, a recombinant human hepatocyte growth factor naked plasmid injection, has made significant progress, with both the ulcer group and resting pain group of the Phase III clinical trials completing unblinding [2] - The primary endpoint of the NL003 resting pain group showed a significant improvement over the placebo group, with a p-value of less than 0.0001, indicating statistical significance [2] - NL003 successfully passed registration inspection in September 2024, with its production process meeting GMP standards, establishing a stable and controllable production and quality management system [2] Group 3: Production and Commercialization - The company's biopharmaceutical industrialization project in Tongzhou, Beijing, has achieved important milestones, including the completion of municipal power capacity approval and design for various facilities [3] - The completion of this project is expected to significantly enhance the company's production capacity in the biopharmaceutical field, providing strong support for the commercialization of innovative drugs [3] - In October 2024, the company opened a branch in Shanghai, further facilitating its commercialization efforts [3] Group 4: Financial Forecast - The company forecasts revenues of 88 million yuan, 185 million yuan, and 371 million yuan for 2025, 2026, and 2027 respectively, with corresponding EPS of -0.19, -0.01, and 0.30 yuan [4] - The current stock price corresponds to PE ratios of -114.7, -2402.2, and 70.6 times for the years 2025, 2026, and 2027 respectively, with an initial coverage rating of "buy" [4]

证券代码：430047 证券简称：诺思兰德 公告编号：2025-040 北京诺思兰德生物技术股份有限公司 关于申请银行贷款的公告 本公司及董事会全体成员保证公告内容的真实、准确和完整，没有虚假 记载、误导性陈述或者重大遗漏，并对其内容的真实性、准确性和完整性承 担个别及连带法律责任。 一、向银行申请贷款的基本情况 为了满足公司发展的资金需求，北京诺思兰德生物技术股份有限公司（以下 简称"公司"）拟向上海浦东发展银行股份有限公司北京分行申请不超过 3,000 万元人民币的贷款额度，额度使用期限为自协议签订日至 2026 年 5 月 26 日（可 循环使用，担保方式为信用），具体融资品种为流动资金贷款。上述贷款额度为 公司可使用的贷款额度，不等于公司的实际贷款金额，实际贷款金额以银行与公 司实际发生的金额为准，具体将视公司实际经营需求决定，其他借款事项、借款 时间、金额和用途等，公司将根据实际需要与银行协商确定。 上述计划事项自董事会审议通过之日起一年内实施，并授权公司法定代表人 代表公司与银行签订相关协议文件（包括但不限于申请书、合同、协议、凭证等 文件）。本次申请贷款额度是公司实现业务发展及经营的正常所需，对 ...

证券代码：430047 证券简称：诺思兰德 公告编号：2025-039 北京诺思兰德生物技术股份有限公司 第六届董事会第十七次会议决议公告 7.召开情况合法、合规、合章程性说明： 本公司及董事会全体成员保证公告内容的真实、准确和完整，没有虚假记载、 误导性陈述或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连 带法律责任。 一、会议召开和出席情况 （一）会议召开情况 1.会议召开时间：2025 年 6 月 16 日 2.会议召开地点：北京市海淀区上地开拓路 5 号 A406 室会议室 3.会议召开方式：现场及通讯方式 4.发出董事会会议通知的时间和方式：2025 年 6 月 13 日以书面方式发出 5.会议主持人：董事长许松山先生 6.会议列席人员：监事、高级管理人员 本次董事会的召集、召开和议案审议程序符合《公司法》及《公司章程》的 有关规定，表决结果合法有效。 （二）会议出席情况 会议应出席董事 9 人，出席和授权出席董事 9 人。 董事许日山、陈垒、王英典、徐辉、任自力因公差以通讯方式参与表决。 二、议案审议情况 （一）审议通过《关于公司拟申请银行贷款的议案》 1.议案内容： 为了满足公司发展 ...

证券代码：430047 证券简称:诺思兰德 公告编号：2025-038 北京诺思兰德生物技术股份有限公司股票交易异常波动公告 本公司及董事会全体成员保证公告内容的真实、准确和完整，没有虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连带法律责任。 一、股票交易异常波动的具体情况 公司股票最近 3 个有成交的交易日（2025 年 5 月 29 日至 2025 年 6 月 3 日）以内收盘 价涨幅偏离值累计达到 40.97%，根据《北京证券交易所交易规则（试行）》的有关规定，属 于股票交易异常波动情形。 二、公司关注并核实的相关情况 1、 核实对象： 公司控股股东、实际控制人及其一致行动人，持股 5%以上股东，在任的董事、监事及 高级管理人员。 3、 核实结论： 前期公告的事项不存在需要更正、补充之处,未发现可能或已经对本公司股票交易价格 产生较大影响的媒体报道或市场传闻，不涉及热点概念事项；近期公司经营情况及内外部经 营环境未发生重大变化；公司、控股股东和实际控制人不存在关于本公司的应披露而未披露 的重大事项，或处于筹划阶段的重大事项；不存在其他可能对股价产生较大影响的重大事件。 ...

Core Insights - The innovative drug sector is experiencing strong performance driven by multiple catalysts, including the approval of 11 innovative drugs by the National Medical Products Administration, showcasing the commercialization potential of pharmaceutical companies [4] - China's pharmaceutical companies are achieving breakthroughs through technological innovation and international expansion, with a significant increase in the number of innovative drugs under development, reaching 4,804 by 2024, making China the second globally after the US [4] - The government is providing comprehensive support for innovative drugs, with policies aimed at enhancing the entire value chain from research and development to payment, which is expected to improve the commercialization process for innovative drugs [4] Industry Analysis - The demand for innovative drugs is driven by an aging population and unmet medical needs in areas such as cancer and autoimmune diseases, with the elderly population expected to reach 310 million by the end of 2024, accounting for 22% of the total population [4] - The penetration rate of innovative drugs for autoimmune diseases remains low, indicating substantial market demand [4] Company-Specific Insights - **NuoSiLanDe**: An innovative biotech company with its first gene therapy drug expected to be approved by 2025, targeting new pathways and preparing for commercialization [4][5] - **KangLeWeiShi**: Focused on HPV vaccines, with significant progress in its pipeline, including a three-valent HPV vaccine expected to be approved by 2025 [4] - **DeYuan Pharmaceutical**: Specializes in chronic disease markets, with a focus on diabetes and cardiovascular diseases, and is developing a first-class innovative drug in collaboration with WuXi AppTec [4][5] - **JinBo Bio**: Leading in recombinant collagen technology with applications in skincare and medical fields, collaborating with various research institutions to advance its product offerings [7] - **HaiNeng Technology**: Aiming to replace imported scientific instruments, particularly in the chromatography sector, with plans to launch a new chromatography workstation software by 2025 [7] - **XinZhi Bio**: Focused on life science instruments, with a strategy to streamline its product offerings and enhance application scenarios [7] - **FeiYi Pharmaceutical**: Engaged in CDMO business, providing services to major pharmaceutical companies in Japan and South Korea, with plans to expand into cardiovascular drug production [7]

A股创新药板块午后持续冲高，舒泰神、冠昊生物20cm涨停，诺思兰德大涨18%，华纳药厂涨超17%， 睿智医药、北陆药业跟涨。 ...

证券代码：430047 证券简称：诺思兰德 公告编号：2025-037 北京诺思兰德生物技术股份有限公司 投资者关系活动记录表 □新闻发布会 □分析师会议 □路演活动 □其他 二、 投资者关系活动情况 本公司及董事会全体成员保证公告内容的真实、准确和完整，没有虚假记载、 误导性陈述或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连 带法律责任。 一、 投资者关系活动类别 √特定对象调研 □业绩说明会 □媒体采访 □现场参观 活动时间：2025 年 5 月 22 日 活动地点：北京市通州区靓丽五街 3 号院 7 号楼 汇恩兰德会议室 参会单位及人员：国盛证券、申万宏源证券、开源证券、中泰证券、中金公 司、中国银河证券、中邮证券、西南证券、首创证券、东吴证券、东北证券、招 商基金、金长川资本、北京青创伯乐投资、真科私募基金、北京量化投资、中承 东方资产、景策基金、风炎投资、北京昊青私募基金、明汯投资、北京钇沣资本 等机构（排名不分先后） 上市公司接待人员：董事长兼总经理：许松山先生；董事、副总经理：聂李 亚先生、韩成权先生；董事、财务总监兼董事会秘书：高洁女士 三、 投资者关系活动主要内容 本次调研活动 ...

□现场参观 证券代码：430047 证券简称：诺思兰德 公告编号：2025-037 北京诺思兰德生物技术股份有限公司 投资者关系活动记录表 本公司及董事会全体成员保证公告内容的真实、准确和完整，没有虚假记载、 误导性陈述或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连 带法律责任。 一、 投资者关系活动类别 √特定对象调研 □业绩说明会 □媒体采访 □新闻发布会 □分析师会议 □路演活动 □其他 二、 投资者关系活动情况 活动时间：2025 年 5 月 22 日 活动地点：北京市通州区靓丽五街 3 号院 7 号楼 汇恩兰德会议室 参会单位及人员：国盛证券、申万宏源证券、开源证券、中泰证券、中金公 司、中国银河证券、中邮证券、西南证券、首创证券、东吴证券、东北证券、招 商基金、金长川资本、北京青创伯乐投资、真科私募基金、北京量化投资、中承 东方资产、景策基金、风炎投资、北京昊青私募基金、明汯投资、北京钇沣资本 等机构（排名不分先后） 上市公司接待人员：董事长兼总经理：许松山先生；董事、副总经理：聂李 亚先生、韩成权先生；董事、财务总监兼董事会秘书：高洁女士 三、 投资者关系活动主要内容 本次调研活动 ...