格隆汇11月6日丨科济药业-B(02171.HK)公告，11月6日耗资2630.8万港元回购173.4万股。 ...

智通财经APP讯，科济药业-B(02171)发布公告，于2025年11月6日斥资2630.78万港元回购173.4万股股 份。 ...

FF305 翌日披露報表 (股份發行人 ── 已發行股份或庫存股份變動、股份購回及/或在場内出售庫存股份) 表格類別： 股票 狀態： 新提交 公司名稱： 科濟藥業控股有限公司 呈交日期： 2025年11月6日 如上市發行人的已發行股份或庫存股份出現變動而須根據《香港聯合交易所有限公司（「香港聯交所」）證券上市規則》(「《主板上市規則》」)第13.25A條 / 《香港聯合交易所有限公司GEM證券 上市規則》(「《GEM上市規則》」)第17.27A條作出披露，必須填妥第一章節 。 | 第一章節 | | | | | | | | --- | --- | --- | --- | --- | --- | --- | | 1. 股份分類 | 普通股 | 股份類別 不適用 | | 於香港聯交所上市 | 是 | | | 證券代號 (如上市) | 02171 | 說明 | | | | | | A. 已發行股份或庫存股份變動 | | | | | | | | | | 已發行股份（不包括庫存股份）變動 | | 庫存股份變動 | | | | | 事件 | 已發行股份（不包括庫存股份）數 目 | 佔有關事件前的現有已發 行股份（不包括庫存 ...

股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年10月31日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: 科濟藥業控股有限公司 呈交日期: 2025年11月6日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 02171 | 說明 | | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | | 法定/註冊股本 | | | 上月底結存 | | | 200,000,000,000 | USD | | 0.00000025 | USD | | 50,000 | | 增加 / 減少 (-) | | | | | | | USD | | | | 本月底結存 | | | 200,000,000,000 | USD | | 0.00000025 | USD | | 50,000 | ...

11月4日，国家医保局发布消息表示，10月30日至11月3日，国家医保局组织开展2025年国家基本医保药 品目录谈判竞价和商保创新药目录价格协商工作，120家内外资企业现场参与，其中参与基本医保药品 目录谈判竞价的目录外药品127个，参与商保创新药目录价格协商的药品24个。后续相关技术、行政和 法律程序完成后，新版基本医保药品目录及首版商保创新药目录拟于12月第一个周末在广州线上线下同 步发布，明年1月1日起正式实施。 每年一次的医保谈判是影响中国医药行业的大事，今年最大的亮点是商保创新药目录，这也是首次设立 商保创新药目录。根据此前公布的数据，今年商保创新药目录申报信息共有141份，涉及药品通用名141 个，121个通过形式审查，其中同时申报基本医保目录和商保创新药目录的有79个。 国家基本医保的定位是"保基本"，以百万元一针的CAR-T疗法等高值创新药始终未能如愿通过医保谈判 进入基本医保目录。业内普遍认为，这与国家医保谈判"50万不谈，30万不进"的规则有关。商保创新药 目录就是聚焦创新程度很高、临床价值巨大、患者获益显著，但因超出"保基本"定位暂时无法纳入基本 医保目录的药品。国家医保局曾对外表示，将 ...

Group 1 - MSCI announced the results of the November index review, with adjustments effective after the market close on November 24 [1] - The MSCI Global Small Cap Index will include 22 new stocks, such as Gilead Sciences (01672) and Meili Tianyuan Healthcare (02373) [1] - 17 stocks will be removed from the MSCI Global Small Cap Index, including China Gold International (02099) and China Nonferrous Mining (01258) [1] Group 2 - The MSCI Hong Kong Index will add 7 new stocks, including Chow Sang Sang (00116) and MGM China (02282) [2] - Stocks removed from the MSCI Hong Kong Index include Kintor Pharmaceutical (02171) and HKT Trust (00215) [2][3]

Group 1 - MSCI announced the results of the November index review, with adjustments effective after the market close on November 24 [1] - A total of 22 stocks were added to the MSCI Global Small Cap Index, including companies such as Genscript Biotech (01672) and Youzan (08083) [1] - 17 stocks were removed from the MSCI Global Small Cap Index, including China Gold International (02099) and Longi Green Energy (601869) [1] Group 2 - The MSCI Hong Kong Index included 7 new stocks, such as Chow Sang Sang (00116) and MGM China (02282) [2] - The MSCI Hong Kong Index removed stocks like Kintor Pharmaceutical (02171) and HKT Trust (00215) [2][3]

Core Insights - The National Medical Insurance Negotiation concluded on November 4, with 120 companies participating, involving 127 off-list drugs and 24 drugs for commercial insurance innovation [1] Group 1: Introduction of Commercial Health Insurance Innovation Drug Directory - The "Commercial Health Insurance Innovation Drug Directory" was introduced for the first time this year, building on the existing medical insurance directory adjustment mechanism [2] - A total of 121 drug names passed the formal review for the commercial health insurance innovation drug directory, with 79 drugs applying for both the basic medical insurance and the commercial health insurance directories [2] Group 2: CAR-T Therapy and Pricing Negotiations - The high-priced CAR-T therapies are highlighted as a significant focus in the commercial health insurance innovation drug directory [4] - Five CAR-T therapies have passed the formal review for the commercial insurance directory, with three also applying for the basic medical insurance directory [5] - The only CAR-T therapy priced below one million yuan is the one from Huyuan Biotechnology, priced at 999,000 yuan per injection, and negotiations for this therapy have reportedly gone smoothly [5][6] Group 3: Market Dynamics and Future Implementation - The introduction of the commercial health insurance innovation drug directory is seen as a key step to break the payment deadlock, potentially lowering patient out-of-pocket expenses and expanding the patient population [6] - The new basic medical insurance drug directory and the first commercial health insurance innovation drug directory are expected to be released in early December, with implementation starting on January 1 of the following year [6]

本报讯 （记者矫月）据科济药业控股有限公司（以下简称"科济药业"，02171.HK）官微消息，11月3 日，科济药业公布了基于公司自主研发的THANK-u Plus®平台开发的通用型BCMA CAR-T产品CT0596 治疗复发/难治性多发性骨髓瘤（R/R MM）的临床数据，以及通用型CD19/CD20 CAR-T产品CT1190B 治疗复发/难治性非霍奇金淋巴瘤（R/R NHL）的临床数据。数据显示，这两款通用型CAR-T产品均具 有初步良好的安全性和令人鼓舞的疗效信号。 业内人士分析，当前已上市的CAR-T产品均为自体CAR-T产品，自体CAR-T是一种高端定制疗法，医生 需要从患者体内获取T细胞，在体外通过基因工程在T细胞表面表达针对癌症抗原的嵌合抗原受体 （CAR），然后将增殖后的细胞输回患者体内，制备周期长达3-4周左右，存在生产难度大、成本高、 患者等待时间长的问题，限制大规模的临床使用。 据了解，自体CAR-T"一人一批"的定制模式导致单剂价格超百万元，在当前美国自体CAR-T单剂价格最 低要37万美元，国内目前主流价格在120万元左右，美国仅有20%符合条件的患者能接受治疗，中国这 一比例更低 ...

Core Insights - Kintor Pharmaceutical (02171.HK) announced clinical data for its universal BCMA CAR-T product CT0596 and universal CD19/CD20 CAR-T product CT1190B, both showing promising safety and efficacy signals for treating relapsed/refractory multiple myeloma (R/R MM) and non-Hodgkin lymphoma (R/R NHL) respectively [1][2] Group 1: Product Development - CT0596 is a universal CAR-T cell therapy targeting BCMA, currently undergoing investigator-initiated clinical trials for R/R MM and plasma cell leukemia (PCL), with plans to submit an IND application in the second half of 2025 [1] - CT1190B targets CD19/CD20 and is involved in clinical trials for treating relapsed/refractory B-cell non-Hodgkin lymphoma (B-NHL) and severe refractory systemic lupus erythematosus (SLE) or refractory/progressive systemic sclerosis (SSc) [2] Group 2: Company Overview - Kintor Pharmaceutical is a biopharmaceutical company focused on developing innovative CAR-T cell therapies to address unmet clinical needs, including hematologic malignancies, solid tumors, and autoimmune diseases [2] - The company has established end-to-end capabilities in CAR-T cell research and development, from target discovery to commercial-scale production, positioning itself as a leading global player in CAR-T therapy [2] - Kintor currently has 10 CAR-T pipeline products, including 4 autologous CAR-T and 6 universal CAR-T, all of which are self-developed with global rights [2]