证券之星消息，12月23日动物保健板块较上一交易日上涨0.36%，生物股份领涨。当日上证指数报收于 3919.98，上涨0.07%。深证成指报收于13368.99，上涨0.27%。动物保健板块个股涨跌见下表： 从资金流向上来看，当日动物保健板块主力资金净流出2100.59万元，游资资金净流出1797.28万元，散 户资金净流入3897.87万元。动物保健板块个股资金流向见下表： 以上内容为证券之星据公开信息整理，由AI算法生成（网信算备310104345710301240019号），不构成投资建议。 ...

Core Viewpoint - Junshi Biosciences has submitted its IPO application to the Hong Kong Stock Exchange, aiming to enter the biotech sector with its innovative TIL therapies, GC101 and GC203, which show promising clinical results in treating solid tumors [1] Company Overview - Junshi Biosciences, established six years ago, focuses on innovative cell therapies and drug development for solid tumors [1] - The company has reported cumulative losses exceeding 350 million yuan from 2023 to the first half of 2025, with cash and cash equivalents at 63.635 million yuan as of June 30, 2025 [1][5] Product Pipeline - GC101, a TIL therapy, has shown an objective response rate (ORR) of 41.7% in patients with metastatic non-small cell lung cancer and 30% in advanced melanoma patients, positioning it as a potential first TIL therapy approved in China [1][3] - GC203, the world's first non-viral vector gene-modified TIL therapy, has demonstrated a 33.3% ORR in heavily pre-treated ovarian cancer patients [4] Market Potential - The global TIL therapy market is expected to reach $4.5 billion by 2035, with China's market projected to grow at a compound annual growth rate (CAGR) of 40% from 2030 to 2035, outpacing global growth [4] Financial Challenges - The company has not yet generated product sales revenue and is experiencing increasing R&D expenditures, which reached 57.62 million yuan in 2023 and are projected to rise further [5] - Junshi Biosciences faces significant cash flow pressure due to ongoing losses and rising operational costs [5] Competitive Landscape - The TIL therapy market is highly competitive, with over ten similar therapies in development globally, including Iovance's approved product, Amtagvi [6] - Junshi Biosciences must continue to build advantages in clinical progress, efficacy data, and cost control to stand out in the competitive environment [6] Regulatory Environment - Positive signals from industry policies, such as breakthrough therapy designations and conditional approval processes, are accelerating the approval of innovative cell therapies in China [6]

从资金流向上来看，当日动物保健板块主力资金净流出1.39亿元，游资资金净流入5021.79万元，散户资 金净流入8897.91万元。动物保健板块个股资金流向见下表： 以上内容为证券之星据公开信息整理，由AI算法生成（网信算备310104345710301240019号），不构成投资建议。 证券之星消息，12月22日动物保健板块较上一交易日上涨2.22%，生物股份领涨。当日上证指数报收于 3917.36，上涨0.69%。深证成指报收于13332.73，上涨1.47%。动物保健板块个股涨跌见下表： ...

Group 1 - The core point of the news is that Jin Yu Biological Technology Co., Ltd. has seen a stock price increase of 5.01%, reaching 15.72 yuan per share, with a trading volume of 779 million yuan and a turnover rate of 4.53%, resulting in a total market capitalization of 17.477 billion yuan [1] - The company, established on March 13, 1993, and listed on January 15, 1999, primarily engages in the research, production, and sales of veterinary biological products, with main business revenue composition being 94.42% from biopharmaceuticals, 3.18% from other income, and 2.40% from supplementary sources [1] Group 2 - From the perspective of major fund holdings, E Fund has one fund heavily invested in Jin Yu Biological, specifically the E Fund CSI Modern Agriculture Theme ETF (562900), which increased its holdings by 19,600 shares in the third quarter, totaling 239,100 shares, accounting for 2.79% of the fund's net value, ranking as the eighth largest holding [2] - The E Fund CSI Modern Agriculture Theme ETF (562900) was established on December 2, 2021, with a latest scale of 826.209 million yuan, showing a year-to-date return of 10.69% and a one-year return of 8.05%, with a cumulative loss of 20.3% since inception [2]

Core Insights - The animal health sector experienced a slight increase of 0.42% on December 19, with Huisheng Biological leading the gains [1] - The Shanghai Composite Index closed at 3890.45, up 0.36%, while the Shenzhen Component Index closed at 13140.22, up 0.66% [1] Stock Performance - Huisheng Biological (300871) closed at 20.75, with a rise of 2.47% and a trading volume of 45,200 shares, amounting to a transaction value of 92.96 million yuan [1] - Other notable performers included: - Qudongli (920275) at 9.27, up 2.43% [1] - Shenlian Biological (688098) at 9.01, up 2.15% [1] - Xianfeng Holdings (002141) at 3.74, up 1.91% [1] - Ruipu Biological (300119) at 19.60, up 1.87% [1] Capital Flow - The animal health sector saw a net outflow of 129 million yuan from institutional investors, while retail investors contributed a net inflow of 157 million yuan [2][3] - The detailed capital flow for selected stocks showed: - Xianfeng Holdings (002141) had a net inflow of 6.89 million yuan from institutional investors [3] - Ruipu Biological (300119) experienced a net outflow of 15.98 million yuan from institutional investors but a net inflow of 11.27 million yuan from retail investors [3] - Qudongli (920275) had a net inflow of 2.22 million yuan from retail investors [3]

重要内容提示： 登录新浪财经APP 搜索【信披】查看更多考评等级 证券代码：688739 证券简称：成大生物公告编号：2025-060 辽宁成大生物股份有限公司 关于部分募集资金投资项目内部投资结构调整的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重大遗漏，并对其内容 的真实性、准确性和完整性承担法律责任。 ● 部分募投项目内部投资结构调整情况：为进一步优化募集资金使用效率，合理配置资源，辽宁成大生 物股份有限公司（以下简称"公司"）拟对部分募集资金投资项目（以下简称"募投项目"）的内部投资结 构进行调整。本次募投项目内部投资结构调整包含两项内容：一是公司拟终止"人用疫苗研发项目"项下 子项目"b型流感嗜血杆菌结合疫苗"（以下简称"hib疫苗"）的开发；二是针对"生物技术产品研发生产基 地项目"内部投资结构及具体金额进行优化调整，以匹配项目建设节奏与实际需求。本次调整为募投项 目内部层面的投资结构优化，不涉及募投项目投资总额、实施主体及实施地点的变更，调整后可保障相 关项目规范有序推进，与公司整体发展战略高度契合。 公司于2025年12月18日召开第五届董事会第二十五次会议，审 ...

10月28日公司发布的三季报数据显示，前三季度公司共实现营业收入10.42亿元，同比增长7.38%，实现 净利润1.61亿元，同比下降4.85%。（数据宝） 生物股份12月17日交易公开信息 | 买/ | 会员营业部名称 | 买入金额（万 | 卖出金额（万 | | --- | --- | --- | --- | | 卖 | | 元） | 元） | | 买一 | 沪股通专用 | 3546.68 | | | 买二 | 东方财富证券股份有限公司拉萨东环路第一证券营业部 | 2955.62 | | | 买三 | 华泰证券股份有限公司昆山黑龙江北路证券营业部 | 2405.53 | | | 买四 | 中信建投证券股份有限公司杭州萍水西街证券营业部 | 2078.65 | | | 买五 | 财通证券股份有限公司宁海金融中心证券营业部 | 2042.86 | | | 卖一 | 机构专用 | | 9482.71 | | 卖二 | 沪股通专用 | | 9038.38 | | 卖三 | 中信证券股份有限公司大连分公司 | 3316.75 | | --- | --- | --- | | 卖四 | 平安证券股份有限公司深圳深南东路罗 ...

Group 1 - The core viewpoint of the article highlights the significant net buying and selling activities of stocks on December 17, with specific focus on the stocks that appeared on the trading leaderboard [1] - Among the stocks with net buying, ShenNan Circuit had the highest net purchase amount of 146 million yuan, followed by Shengxin Lithium Energy with 109 million yuan, Aerospace Machinery with 85.18 million yuan, and Guangxun Technology with 66.42 million yuan [1] - The stocks with the highest net selling included XueRen Group with a net selling amount of 143 million yuan, followed by Biological Shares with 54.91 million yuan and Juguang Technology with 53.47 million yuan [1]

Market Overview - The Shanghai Composite Index rose by 1.19% on December 17, with 28 out of 33 sectors experiencing gains, led by the communication and non-ferrous metals sectors, which increased by 5.07% and 3.03% respectively [1] - The agriculture, forestry, animal husbandry, and fishery sector had the largest decline, falling by 0.54% [1] Capital Flow Analysis - The net inflow of capital in the two markets was 9.51 billion yuan, with 16 sectors seeing net inflows [1] - The communication sector had the highest net inflow of 6.45 billion yuan, coinciding with its 5.07% increase [1] - The electronics sector also saw a significant net inflow of 6.34 billion yuan, with a daily increase of 2.48% [1] Agriculture, Forestry, Animal Husbandry, and Fishery Sector - This sector experienced a decline of 0.54%, with a net outflow of 1.94 billion yuan [2] - Out of 105 stocks in this sector, 60 rose, while 39 fell, including 3 that hit the daily limit down [2] - The top three stocks with the highest net inflow were COFCO Sugar Industry (35.26 million yuan), Beidahuang (33.62 million yuan), and Muyuan Foods (31.82 million yuan) [2] Capital Outflow in Agriculture, Forestry, Animal Husbandry, and Fishery Sector - The top three stocks with the highest net outflow were Pingtan Development (-1.28 billion yuan), Luoniushan (-264.82 million yuan), and Biological Shares (-142.17 million yuan) [4] - Pingtan Development saw a significant drop of 10.03%, while Luoniushan and Biological Shares fell by 9.19% and 10.01% respectively [4]

证券之星消息，12月17日动物保健板块较上一交易日下跌2.24%，生物股份领跌。当日上证指数报收于 3870.28，上涨1.19%。深证成指报收于13224.51，上涨2.4%。动物保健板块个股涨跌见下表： 从资金流向上来看，当日动物保健板块主力资金净流出1.42亿元，游资资金净流入3867.16万元，散户资 金净流入1.03亿元。动物保健板块个股资金流向见下表： 以上内容为证券之星据公开信息整理，由AI算法生成（网信算备310104345710301240019号），不构成投资建议。 ...