Core Viewpoint - The demand for insulin in China is rapidly increasing due to the large diabetic patient population, with Aspart insulin being a key product that effectively controls postprandial hyperglycemia and is now more accessible due to its inclusion in the medical insurance catalog [1][7]. Market Overview - Aspart insulin is a commonly used rapid-acting insulin analog, primarily for controlling blood sugar in type 1 and type 2 diabetes patients, with effects starting within 10-20 minutes and lasting about 4-6 hours [2][3]. - The market size for Aspart insulin in China is projected to reach 8.451 billion yuan in 2024, representing a year-on-year growth of 5.33% and accounting for 31.1% of the overall insulin market [1][7]. Market Policies - The Chinese government has implemented various policies to regulate the insulin industry, ensuring quality and safety while promoting healthy and high-quality development [3]. Industry Chain - The upstream of the Aspart insulin industry includes animal-derived insulin raw materials, intermediates, active pharmaceutical ingredients, packaging materials, and pharmaceutical equipment. The midstream consists of Aspart insulin production companies, while the downstream includes medical institutions, pharmacies, e-commerce channels, and end consumers [4][5]. Patient Demographics - The prevalence of diabetes in China is on the rise, with an estimated 148 million diabetic patients by 2024, marking a year-on-year increase of 4.89%, which drives the demand for Aspart insulin [6]. Competitive Landscape - The centralized procurement policy has reshaped the competitive landscape of the insulin market, leading to price reductions but also providing more market opportunities for selected companies. As of April 2024, six companies were selected for Aspart insulin in the national procurement process, indicating a trend towards increased market share for domestic products [8][9]. Company Profiles - **Ganli Pharmaceutical**: Engaged in the research, production, and sales of insulin analogs, with a projected revenue of 3.045 billion yuan and a gross profit of 2.279 billion yuan in 2024, achieving a gross margin of 74.83% [10]. - **Tonghua Dongbao Pharmaceutical**: Focused on drug research and production, with a projected revenue of 2.01 billion yuan and a gross profit of 1.485 billion yuan in 2024, achieving a gross margin of 73.90% [11]. Future Development Trends - The inclusion of Aspart insulin in the medical insurance catalog will continue to impact its market sales, with ongoing adjustments in reimbursement policies and centralized procurement driving companies to optimize pricing strategies and enhance product accessibility in grassroots medical markets [12].

Market Overview - The Shanghai Composite Index rose by 0.37% on September 17, with 20 industries experiencing gains, led by the power equipment and automotive sectors, which increased by 2.55% and 2.05% respectively [1] - Conversely, the agriculture, forestry, animal husbandry, and fishery sectors, along with retail, saw declines of 1.02% and 0.98% respectively [1] - The pharmaceutical and biotechnology sector fell by 0.23% [1] Capital Flow Analysis - The main capital outflow from the two markets totaled 38.306 billion yuan, with five industries seeing net inflows [1] - The power equipment sector led the net inflow with 1.835 billion yuan, followed by the automotive sector with 1.142 billion yuan [1] - The non-bank financial sector experienced the largest net outflow, totaling 5.229 billion yuan, followed by the computer sector with a net outflow of 4.455 billion yuan [1] Pharmaceutical and Biotechnology Sector - The pharmaceutical and biotechnology sector saw a net outflow of 3.977 billion yuan, with 474 stocks in the sector; 135 stocks rose while 327 fell [2] - The top net inflow stocks included WuXi AppTec with 352 million yuan, followed by Hengrui Medicine and Boteng Co., with inflows of 312 million yuan and 55.426 million yuan respectively [2] - Nine stocks in the sector experienced net outflows exceeding 100 million yuan, with the largest outflows from Guangsheng Tang, Sino Medical, and Ganli Pharmaceutical, amounting to 253 million yuan, 164 million yuan, and 140 million yuan respectively [2] Top Gainers in Pharmaceutical Sector - WuXi AppTec: +2.09%, turnover rate 2.01%, net inflow 351.585 million yuan [2] - Hengrui Medicine: +1.42%, turnover rate 0.92%, net inflow 312.024 million yuan [2] - Boteng Co.: -0.93%, turnover rate 6.09%, net inflow 55.426 million yuan [2] Top Losers in Pharmaceutical Sector - Guangsheng Tang: -4.40%, turnover rate 9.74%, net outflow -252.737 million yuan [3] - Sino Medical: -1.74%, turnover rate 5.85%, net outflow -164.152 million yuan [3] - Ganli Pharmaceutical: -1.74%, turnover rate 2.88%, net outflow -139.861 million yuan [3]

Overview - The demand for insulin in China is rapidly increasing due to a large diabetic patient population, with the market for insulin glargine projected to reach 6.083 billion yuan in 2024, representing a year-on-year growth of 4.13% and accounting for 22.36% of the overall insulin market [1][9]. Market Policy - The Chinese government has implemented a series of policies to regulate the production, sales, and use of insulin, including insulin glargine, to ensure drug quality and safety, promoting healthy and high-quality industry development [4][5]. Industry Chain - The upstream of the insulin glargine industry includes suppliers of raw materials such as gene-engineered strains, culture media, and packaging materials, while the midstream consists of production companies, and the downstream includes medical institutions and pharmacies [6][7]. Current Development - The prevalence of diabetes in China is on the rise, with an estimated 148 million diabetic patients in 2024, marking a year-on-year increase of 4.89%, which drives the demand for insulin glargine [8][9]. Competitive Landscape - The market is transitioning from foreign dominance to the rise of domestic companies, with a multi-faceted competitive landscape involving original research companies, leading domestic firms, and follow-up entrants. Domestic companies like Ganli Pharmaceutical and Tonghua Dongbao have gained market share through centralized procurement policies [10][11]. Company Profiles - **Ganli Pharmaceutical**: Focuses on the research, production, and sales of insulin analogs, with projected revenue of 3.045 billion yuan and a gross profit of 2.279 billion yuan in 2024, achieving a gross margin of 74.83% [11][12]. - **Tonghua Dongbao**: Engaged in drug research and production, with a focus on diabetes and endocrine treatments, reporting a revenue of 2.01 billion yuan and a gross profit of 1.485 billion yuan in 2024, with a gross margin of 73.90% [12]. Future Trends - Domestic companies are expected to continue improving product quality and reducing the gap with imported products, leading to an increase in market share for domestic insulin glargine as centralized procurement policies advance, and more products may enter the international market [10][12].

Group 1 - The company has approved a share repurchase plan to buy back its own A-shares, with a maximum price of RMB 62.76 per share and a total repurchase fund ranging from RMB 150 million to RMB 300 million, to be executed within 12 months [1][2] - The purpose of the repurchased shares has been adjusted from employee stock ownership plans or equity incentives to cancellation and reduction of registered capital [2] - A total of 3,540,021 shares have been repurchased, accounting for 0.5890% of the company's total share capital, with a total expenditure of approximately RMB 150.07 million [2] Group 2 - Following the cancellation of the repurchased shares, the company's total share capital will decrease from 601,065,290 shares to 597,525,269 shares, and registered capital will reduce from RMB 601,065,290 to RMB 597,525,269 [3] - Creditors are notified that they have 30 days from receiving the notice or 45 days from the announcement date to claim their debts or request guarantees [3][4] - Required documents for creditors to declare their claims include contracts, agreements, and other proof of debt, along with identification and authorization documents if applicable [3]

Core Points - The company announced a share repurchase plan with a total expected amount between RMB 150 million and RMB 300 million, with a maximum repurchase price of RMB 62.76 per share [1][2] - The actual number of shares repurchased is 3,540,021, representing 0.5890% of the total share capital, with a total expenditure of approximately RMB 150.07 million [3][4] - The purpose of the repurchased shares has been adjusted from employee stock ownership plans to cancellation and reduction of registered capital [2][3] Repurchase Plan Details - The repurchase period is from September 5, 2024, to September 4, 2025, and the company has complied with the regulations during the repurchase process [3][4] - The repurchase was conducted through centralized bidding, with the highest transaction price at RMB 45.14 per share and the lowest at RMB 37.65 per share, resulting in an average price of RMB 42.39 per share [3][4] - The company plans to cancel the repurchased shares on September 8, 2025, and will notify creditors regarding the capital reduction [6][7] Share Capital Changes - Before the repurchase, the total number of shares was 601,065,290, and after the cancellation of the repurchased shares, it will be reduced to 597,525,269 [6] - The repurchased shares will be canceled, leading to a decrease in the company's registered capital, which aligns with the long-term interests of the company and its investors [3][7]

Group 1 - Gannee Pharmaceutical has completed a share buyback, acquiring a total of 3.540021 million shares, which represents 0.589% of the company's total share capital [1] - The highest transaction price during the buyback was 45.14 CNY per share, while the lowest was 37.65 CNY per share, with an average buyback price of 42.39 CNY per share [1] - The total amount spent on the buyback was approximately 150 million CNY [1] Group 2 - For the year 2024, Gannee Pharmaceutical's revenue composition is entirely from the pharmaceutical manufacturing industry, accounting for 100.0% [1] - The current market capitalization of Gannee Pharmaceutical is 45 billion CNY [2]

证券代码：603087 证券简称：甘李药业 公告编号：2025-064 甘李药业股份有限公司 关于股份回购实施结果暨股份变动的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： | 回购方案首次披露日 | 2024/9/6 | | | | | | --- | --- | --- | --- | --- | --- | | 回购方案实施期限 | 年 月 月 2024 9 9 4 | 5 | 日~2025 | 年 | 日 | | 预计回购金额 | 15,000万元~30,000万元 | | | | | | 回购价格上限 | 62.76元/股 | | | | | | 回购用途 | √减少注册资本 □用于员工持股计划或股权激励 | | | | | | | □为维护公司价值及股东权益 | | | | | | 实际回购股数 | 354.0021万股 | | | | | | 实际回购股数占总股本比例 | 0.5890% | | | | | | 实际回购金额 | 15,006.9654万元 | | | | | | 实际回购价 ...

证券代码：603087 证券简称：甘李药业 公告编号：2025-065 1 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 一、本次回购股份注销并减少注册资本的情况暨通知债权人的原因 中竞价交易方式实施回购股份 3,540,021 股，占公司总股本的比例为 0.5890%， 成交最高价为 45.14 元/股，成交最低价为 37.65 元/股，已支付的资金总额约为人 民币 15,006.9654 万元（不含交易费用），公司本次回购方案已实施完毕。具体内 容详见公司于 2025 年 9 月 8 日在上海证券交易所披露的《关于股份回购实施结 果暨股份变动的公告》（公告编号：2025-064）。 二、需债权人知晓的相关信息 上述回购股份 3,540,021 股注销完成后，公司总股本将由 601,065,290 股减少 至 597,525,269 股，注册资本将由 601,065,290 元减少至 597,525,269 元（鉴于公 司前次回购注销部分限制性股票并减少注册资本尚未完成，公司总股本暂按 601,065,290 股计算，最终 ...

Core Viewpoint - 甘李药业 has shown significant growth in stock price and financial performance, indicating strong market interest and operational success [1][2]. Financial Performance - As of June 30, 甘李药业 reported a revenue of 2.067 billion yuan, representing a year-on-year increase of 57.18% [2]. - The net profit attributable to shareholders reached 604 million yuan, marking a substantial growth of 101.96% compared to the previous year [2]. - Cumulatively, the company has distributed 1.612 billion yuan in dividends since its A-share listing, with 1.018 billion yuan distributed over the last three years [3]. Stock Performance - The stock price of 甘李药业 increased by 69.72% year-to-date, with a recent 5-day increase of 0.32%, a 20-day increase of 19.00%, and a 60-day increase of 31.04% [1]. - The stock was trading at 73.16 yuan per share, with a market capitalization of 43.974 billion yuan as of September 5 [1]. Shareholder Structure - As of June 30, the number of shareholders increased to 77,300, up by 3.08% from the previous period [2]. - The average number of circulating shares per shareholder decreased by 2.99% to 7,165 shares [2]. - Major shareholders include Hong Kong Central Clearing Limited, which increased its holdings by 174,800 shares, and new entrants like Innovation Drug and Southern Alpha Mixed A [3].

Group 1 - The biopharmaceutical ETF (159859) has shown strong performance, rising 1.16% with a trading volume exceeding 94 million yuan, making it the top performer among its peers [1] - The ETF has seen a net inflow of over 61 million yuan over the past three trading days, indicating strong investor interest [1] - The ETF closely tracks the National Index of Biopharmaceuticals (399441.SZ), which covers various sectors including innovative drugs, CXO, vaccines, and blood products [1] Group 2 - The innovative drug ETF Tianhong (517380) is the largest in the market, covering both A-shares and Hong Kong stocks, and is the only ETF tracking the Hang Seng-Hushen-Hong Kong Innovative Drug Selected 50 Index [2] - The Tianhong ETF has also experienced a net inflow of over 64 million yuan over the past three trading days, reflecting positive market sentiment [2] - A recent meeting emphasized the need for comprehensive reforms in drug regulation and innovation, which could positively impact the pharmaceutical industry [2] Group 3 - Overall, the market may face short-term fluctuations, but there are signs of capital rotation, with many undervalued stocks beginning to rebound [3] - The expectation of interest rate cuts and economic recovery may lead to a focus on cyclical sectors in the future [3]