Core Viewpoint - The company reported its Q3 2025 earnings, achieving revenue of 1.869 billion yuan, which is essentially flat year-on-year, and a net profit attributable to shareholders of -120 million yuan, an improvement from -463 million yuan in the same period last year, indicating a reduction in losses and meeting prior expectations [1][2][3]. Financial Performance - For the first three quarters of 2025, the company achieved revenue of 1.869 billion yuan, with a net profit attributable to shareholders of -120 million yuan, compared to -463 million yuan in the previous year, and a non-recurring net profit of -228 million yuan, improving from -497 million yuan year-on-year [3][4]. - In Q3 2025, the company reported revenue of 755 million yuan, a year-on-year increase of 14.45%, driven by steady progress in domestic substitution and accelerated development in automation and multi-omics businesses [3][4]. - The company’s gross margin for the first three quarters was 53.32%, down 8.15 percentage points, primarily due to competitive pressures affecting product margins [8]. Business Segments - The full-read long sequencing business saw a steady increase in instrument sales, with the successful launch of the T7+ product, although instrument sales revenue slightly declined due to product mix effects [4]. - The smart automation business segment has been upgraded to focus on automation, with steady revenue growth in the first three quarters of 2025 [5]. Technological Advancements - The company is actively applying AI technologies in its smart automation business, enhancing its capabilities through new platforms and modules, which are expected to improve efficiency and reduce costs [5]. - A licensing agreement with SwissRockets for the CoolMPS sequencing technology is expected to generate at least 120 million USD in upfront payments and milestone payments, reflecting the company's technological leadership [6][7]. Future Outlook - The company is well-positioned to benefit from the domestic substitution trend, especially following the U.S. restrictions on Illumina, which may enhance its market share [9]. - The global sequencing industry is expected to see improved demand as macroeconomic conditions stabilize, with the company’s losses anticipated to narrow as operational efficiencies improve [9][10]. - Revenue projections for 2025-2027 are 3.041 billion, 3.389 billion, and 3.763 billion yuan, with net profits expected to improve significantly over the same period [10].

证券代码：688114 证券简称：华大智造 公告编号：2025-072 深圳华大智造科技股份有限公司 关于召开2025年第五次临时股东大会的通知 本公司董事会及全体董事保证公告内容不存在任何虚假记载、误导性陈述或 者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 重要内容提示： 股东大会召开日期：2025年11月26日 本次股东大会采用的网络投票系统：上海证券交易所股东大会网络 投票系统 一、 召开会议的基本情况 （一） 股东大会类型和届次 2025年第五次临时股东大会 （二） 股东大会召集人：董事会 （三） 投票方式：本次股东大会所采用的表决方式是现场投票和网络投票 相结合的方式 （四） 现场会议召开的日期、时间和地点 召开日期时间：2025 年 11 月 26 日 15 点 00 分 召开地点：深圳市盐田区梅沙街道云华路 9 号华大时空中心 C 区国际会议 中心 419 会议室 （五） 网络投票的系统、起止日期和投票时间。 网络投票系统：上海证券交易所股东大会网络投票系统 网络投票起止时间：自2025 年 11 月 26 日 至2025 年 11 月 26 日 （六） 融资融券、转融通、约 ...

Core Viewpoint - The medical device sector experienced a slight decline of 0.31% on November 6, with Danaher Biomedical leading the losses, while the overall market indices showed gains, with the Shanghai Composite Index up by 0.97% and the Shenzhen Component Index up by 1.73% [1][2]. Group 1: Market Performance - The Shanghai Composite Index closed at 4007.76, increasing by 0.97% [1]. - The Shenzhen Component Index closed at 13452.42, increasing by 1.73% [1]. - The medical device sector saw a net outflow of 638 million yuan from major funds, while retail investors contributed a net inflow of 446 million yuan [2][3]. Group 2: Individual Stock Performance - Hualan Co., Ltd. (301093) saw a significant increase of 8.53%, closing at 44.00 yuan with a trading volume of 67,500 shares and a transaction value of 293 million yuan [1]. - Danaher Biomedical (920009) led the declines with a drop of 4.69%, closing at 83.50 yuan and a trading volume of 24,900 shares, resulting in a transaction value of 206 million yuan [2]. - Other notable gainers included Furuida (300049) with a 4.32% increase and a closing price of 74.56 yuan, and Kangzhong Medical (688607) with a 3.04% increase, closing at 29.81 yuan [1][2]. Group 3: Fund Flow Analysis - Major funds showed a net outflow in several stocks, including Furuida with a net outflow of 23.99 million yuan, while retail investors showed a net inflow of 25.27 million yuan [3]. - Dongfulong (300171) experienced a net inflow of 21.17 million yuan from major funds, indicating positive sentiment towards the stock [3]. - The overall trend indicates a mixed sentiment in the medical device sector, with some stocks attracting retail interest despite the overall outflow from major funds [2][3].

Core Viewpoint - The biopharmaceutical sector on the STAR Market has shown mixed performance, with the STAR Biopharmaceutical Index declining by 0.60% as of November 6, 2025, while individual stocks exhibited varied movements, indicating a potential for structural recovery in the sector [1][4]. Group 1: Market Performance - The STAR Biopharmaceutical Index decreased by 0.60% as of November 6, 2025, with stocks like Huaheng Biological leading gains at 2.86%, while Yifang Biological experienced the largest decline [1]. - The Jiashi STAR Biopharmaceutical ETF recorded a turnover of 6.67% and a transaction volume of 21.39 million yuan, reaching a new high of 322 million yuan in scale, ranking first among comparable funds [3]. - The Jiashi STAR Biopharmaceutical ETF has seen a net inflow of 56.85 million yuan over the past four days, with a peak single-day net inflow of 16.85 million yuan [3]. Group 2: Fund Performance - As of November 5, 2025, the Jiashi STAR Biopharmaceutical ETF has achieved a one-year net value increase of 26.53%, with the highest monthly return since inception being 23.29% and the longest consecutive monthly gain lasting seven months [3]. - The average monthly return during the rising months of the Jiashi STAR Biopharmaceutical ETF is 7.85% [3]. Group 3: Industry Outlook - Recent adjustments in the pharmaceutical sector are attributed to a recovery in capital market financing and an increase in the scale of innovative drug exports, leading to a rebound in domestic innovative drug research and development [3]. - The outlook for the innovative drug sector remains focused on business development (BD) expectations, with BD activities typically accounting for about 40% of annual transactions in the fourth quarter [3]. - According to data, the top ten weighted stocks in the STAR Biopharmaceutical Index account for 49.74% of the index, indicating a concentration of investment in key players [4][6].

Market Overview - The precision medicine sector experienced a decline of 1.77% on November 4, with TuoJing Life leading the drop [1][2] - The Shanghai Composite Index closed at 3960.19, down 0.41%, while the Shenzhen Component Index closed at 13175.22, down 1.71% [1] Stock Performance - Notable stock performances in the precision medicine sector included: - RenDu Bio (688193) closed at 52.90, up 1.05% with a trading volume of 7076.23 hands and a transaction value exceeding 36.99 million yuan [1] - TuoJing Life (300642) closed at 22.73, down 2.86% with a trading volume of 78,200 hands and a transaction value of 178 million yuan [2] - Other companies like DaAn Gene (002030) and Anke Bio (300009) showed minimal changes, with DaAn Gene remaining flat at 6.57 and Anke Bio down 0.55% to 10.84 [1][2] Capital Flow - The precision medicine sector saw a net outflow of 979 million yuan from institutional investors, while retail investors contributed a net inflow of 642 million yuan [2][3] - Specific stock capital flows indicated: - GuoMai Technology (002093) had a net inflow of 8.61 million yuan from institutional investors, while retail investors saw a net outflow of 15.98 million yuan [3] - TuoJing Life experienced minimal net inflow from institutional investors at 25,000 yuan, with retail investors also showing a slight outflow [3]

Investment Rating - The report maintains an "Overweight" rating for the medical device sector [6] Core Insights - The medical device sector is entering a turning point, driven by innovation and international expansion as key growth drivers [12][29] - The overall revenue for medical device companies in the first three quarters of 2025 was 183.45 billion yuan, a year-on-year decrease of 3.90%, while the net profit excluding non-recurring items was 22.70 billion yuan, down 17.70% [8][15] - Different sub-sectors show significant divergence in performance, with high-value consumables showing a growth of 5.12%, while in vitro diagnostics faced a decline of 13.94% [8][15] Summary by Sections Medical Device Sector Overview - The medical device sector is experiencing a recovery with improved bidding processes and a gradual clearing of high-cost consumables [8][15] - The revenue growth rate for the medical device sector in Q3 2025 was 9.99%, with a net profit growth of 4.87% [9][16] High-Value Consumables - High-value consumables saw a revenue increase of 5.12% in the first three quarters of 2025, with a net profit growth of 1.18% [29] - The sector is stabilizing as it enters the post-collection phase, with significant growth driven by innovation and international expansion [29] Medical Equipment - The medical equipment sector's revenue decreased by 1.02% in the first three quarters of 2025, but showed a positive trend in Q3 with a revenue increase of 9.99% [9][16] - The sector is expected to experience structural differentiation in demand as bidding processes improve [9] Low-Value Consumables - Low-value consumables experienced a revenue decline of 0.75% in the first three quarters of 2025, with a significant drop in net profit by 21.68% [9][16] - The sector's performance is heavily influenced by international market conditions, but there is potential for recovery in Q4 2025 [9] In Vitro Diagnostics - The in vitro diagnostics sector faced a revenue decline of 13.94% in the first three quarters of 2025, with net profit down 32.20% [9][16] - The sector is expected to stabilize by the end of 2025 as negative impacts from policies begin to clear [9]

Investment Rating - The report maintains an "Outperform" rating for the company, with a target price of RMB 75.81 based on a 2025 PS of 11X [4][10]. Core Insights - The company achieved revenue of RMB 1.87 billion in the first three quarters of 2025, showing a slight decrease of 0.01% year-on-year, while net profit attributable to shareholders improved, reducing losses by RMB 343 million to RMB -120 million [4][10]. - As of September 30, 2025, the company had cash reserves of RMB 2.19 billion, a decrease of RMB 427 million from June 30, 2025 [4][10]. - In Q3 2025, the company reported revenue of RMB 755 million, reflecting a growth of 14.45% year-on-year, with net profit attributable to shareholders at RMB -16 million, indicating continued loss reduction [4][11]. - The company effectively controlled its expense ratios, with a gross profit margin of 54.01% (down 4.37 percentage points), and reductions in sales, general and administrative, and R&D expense ratios [4][12]. - The company holds a significant number of patents, with 640 domestic and 492 foreign effective patents, totaling 1,132 effective authorized patents as of September 30, 2025 [4][13]. Financial Summary - Total revenue projections for the upcoming years are as follows: RMB 2.87 billion in 2025, RMB 3.33 billion in 2026, and RMB 3.78 billion in 2027, with respective growth rates of -4.7%, 16.1%, and 13.5% [3]. - The net profit attributable to shareholders is projected to improve significantly from RMB -146 million in 2025 to RMB 151 million in 2027, reflecting a growth rate of 1,538.4% [3]. - The company’s return on equity (ROE) is expected to turn positive by 2027, reaching 1.9% [3].

Group 1: AIA Group (友邦保险) - AIA Group achieved new business value of USD 4.31 billion in the first three quarters of 2025, representing a year-on-year increase of 18% (fixed exchange rate) and 19.3% (actual exchange rate) [5] - The new business value for Q3 2025 alone saw a significant year-on-year growth of 27.1% [5] - Annualized new premiums reached USD 7.49 billion, up 10.9% year-on-year, with Q3 2025 showing a 15.3% increase [5] - Total weighted premium income was USD 35.85 billion, reflecting a 14.2% year-on-year growth, with Q3 2025 also showing a 15.6% increase [5] Group 2: Keda Manufacturing (科达制造) - Keda Manufacturing reported revenue of CNY 12.61 billion and net profit attributable to shareholders of CNY 1.15 billion for the first nine months of 2025, marking increases of 47.2% and 63.5% year-on-year, respectively [6] - In Q3 2025, the company achieved revenue of CNY 4.42 billion, with net profit attributable to shareholders reaching CNY 400 million, reflecting year-on-year growth of 43.9% and 62.6% [6] Group 3: SANY Heavy Industry (三一重工) - SANY Heavy Industry reported revenue of CNY 65.74 billion for the first three quarters of 2025, a year-on-year increase of 13.6%, with net profit attributable to shareholders growing by 46.6% to CNY 7.14 billion [7] - The company's gross margin improved to 27.6%, up 0.7 percentage points year-on-year, while the net margin increased to 11.0%, up 2.4 percentage points [7] Group 4: BYD Electronics (比亚迪电子) - BYD Electronics reported Q3 2025 revenue of CNY 42.68 billion, a year-on-year decrease of 2.0%, with gross profit declining by 20.0% to CNY 2.946 billion, resulting in a gross margin of 6.9% [10] - The decline in revenue and gross profit was attributed to changes in product mix, particularly delays in the delivery of high-margin products for North American clients [10] - Net profit for Q3 2025 decreased by 9.0% to CNY 1.407 billion [10] Group 5: TAL Education Group (好未来) - TAL Education Group reported revenue of USD 861 million for FY26 Q2, representing a year-on-year increase of 39.1%, with net profit attributable to shareholders rising by 116.1% to USD 124 million [11] - The company's Non-GAAP net profit reached USD 136 million, up 82.7% year-on-year, indicating strong growth in both learning services and learning equipment revenue [11] Group 6: Wuliangye Yibin (五粮液) - Wuliangye Yibin's total revenue for the first three quarters of 2025 was CNY 60.945 billion, down 10.26% year-on-year, with net profit attributable to shareholders declining by 13.72% to CNY 21.511 billion [12] - In Q3 2025, total revenue fell sharply by 52.66% to CNY 8.174 billion, with net profit down 65.62% to CNY 2.019 billion [12] Group 7: BGI Genomics (华大智造) - BGI Genomics reported revenue of CNY 1.869 billion for the first three quarters of 2025, a slight decrease of 0.01%, while net loss attributable to shareholders improved by 74.20% to CNY 120 million [13] - In Q3 2025, revenue increased by 14.45% to CNY 755 million, with a significant reduction in net loss by 90.31% to CNY 16 million [13]

Core Viewpoint - The company reported a slight decline in revenue for the first three quarters of 2025, but showed significant improvement in net profit and operational efficiency in Q3 2025, indicating a positive trend in financial performance [4][5]. Financial Performance - For the first three quarters of 2025, the company achieved revenue of 1.869 billion yuan, a year-on-year decrease of 0.01%. The net profit attributable to shareholders was -120 million yuan, a year-on-year reduction in losses of 74.20%. The net profit excluding non-recurring items was -228 million yuan, a year-on-year reduction in losses of 54.17% [4]. - In Q3 2025, the company reported revenue of 755 million yuan, a year-on-year increase of 14.45%. The net profit attributable to shareholders was -16 million yuan, a significant year-on-year reduction in losses of 90.31%. The net profit excluding non-recurring items was -25 million yuan, a year-on-year reduction in losses of 85.33% [4]. Cost Management - In Q3 2025, the company achieved a significant reduction in costs, with the sales expense ratio at 23.19%, down 10.80 percentage points year-on-year, and the management expense ratio at 11.19%, down 12.17 percentage points year-on-year [5]. Research and Development - The company maintained high levels of R&D investment in Q3 2025, with expenditures of 123 million yuan, accounting for 16.27% of revenue. Several innovative products were launched, including the GenSIRO-16 automated sequencing library preparation system and the upgraded MGIEasy Large-scale PCR-FREE whole genome low-depth enzyme-cut library preparation kit [6]. Strategic Partnerships - In Q3 2025, the company established strategic partnerships with Nanjing Practice Medicine, Zhaiguang Biology, and Shinyou Medicine to enhance resource integration and promote advancements in genomics and related fields. The company also launched the ATOPlex Fast targeted sequencing product for the Chikungunya virus, demonstrating its commitment to public health [7].

Investment Rating - The report maintains a "Buy" rating for the company, considering the broad opportunities brought by the continuous promotion of domestic substitution and adherence to globalization [3][5]. Core Insights - The company reported a slight year-on-year decline in revenue of 0.01% for the first three quarters of 2025, with total revenue reaching 1.869 billion yuan. However, the net profit attributable to shareholders improved significantly, with a reduction in losses by 74.20% to -120 million yuan [1][2]. - In Q3 2025, the company achieved a revenue of 755 million yuan, marking a year-on-year growth of 14.45%, and a substantial reduction in net losses by 90.31% compared to the previous year [1][2]. Revenue and Profitability - The company’s revenue for 2023 is projected at 2.911 billion yuan, with a growth rate of -31.19%. By 2025, revenue is expected to increase to 3.250 billion yuan, reflecting a growth rate of 7.87% [4][8]. - The net profit attributable to shareholders is forecasted to improve from -607 million yuan in 2023 to -176 million yuan in 2025, with an EPS of -0.42 yuan for 2025 [4][8]. Cost Management and R&D Investment - The company has successfully reduced costs, with the sales expense ratio decreasing by 10.80 percentage points to 23.19% and the management expense ratio down by 12.17 percentage points to 11.19% in Q3 2025 [2]. - R&D investment remains robust at 123 million yuan in Q3 2025, accounting for 16.27% of revenue, with multiple innovative products launched [2][3]. Strategic Collaborations - The company has formed strategic partnerships with several organizations to enhance resource integration and advance research in genomics and related fields [3]. - The launch of the ATOPlex Fast product for the rapid sequencing of the Chikungunya virus demonstrates the company's commitment to public health and technological advancement [3]. Financial Projections - The company’s projected financials indicate a gradual recovery, with net profits expected to turn positive by 2027, reaching 154 million yuan [4][10]. - The return on equity (ROE) is anticipated to improve from -7.04% in 2023 to 2.03% in 2027, reflecting a positive trend in profitability [10].