Core Insights - The article highlights the successful application of BGI Genomics' sequencing technology in addressing the recent outbreak of Chikungunya virus in Guangdong Province, China, emphasizing the importance of rapid virus tracing and control measures [1][2][3] Group 1: Technology and Application - BGI Genomics' sequencing technology, particularly the DNBSEQ-T1+ and CycloneSEQ G100-ER platforms, plays a crucial role in virus genome sequencing and tracing, achieving over 99.9% coverage in the Chikungunya virus genome analysis [1] - The DNBSEQ-T1+ is noted for its ability to produce Tb-level data within 24 hours and can complete sequencing in as little as 7 hours, significantly enhancing the response efficiency to public health emergencies [1] - The CycloneSEQ platform, utilizing nanopore technology, provides real-time and portable sequencing capabilities, achieving 100% genome coverage in just 20 minutes, which aids in intercepting imported cases at customs [2] Group 2: Market Position and Growth - In 2024, 37 gene sequencing instruments received NMPA approval for clinical testing, with 23 of them based on BGI Genomics' DNBSEQ technology, representing 62% of the total approved devices in China [3] - BGI Genomics has sold over 4,500 sequencing instruments globally, capturing approximately 28.2% of the new sales market share, marking a significant increase of 9.5 percentage points from 2023 [3] - The company is expanding its business beyond core sequencing instruments to include biobanks, cell genomics, and spatial omics, while also exploring applications in judicial and animal disease fields [3] Group 3: Future Outlook - The growing demand across clinical, agricultural, disease control, and customs sectors, combined with the rapid growth of multi-omics business and increasing installation of core sequencing instruments, is expected to drive BGI Genomics' future performance [3] - As the only company globally with both large-scale commercial production of short-read (DNBSEQ) and long-read (CycloneSEQ) sequencing products, BGI Genomics is positioned to expand its market share and achieve steady performance growth [3]

Group 1 - The recent outbreak of Chikungunya virus in Guangdong Province highlights the dual challenges of imported and local transmission, with BGI Genomics' sequencing technology providing critical support for rapid virus tracing [1] - BGI Genomics has deployed nearly 400 SEQ ALL series sequencers across national disease control and customs systems, ready to respond to public health emergencies [1] Group 2 - The T1+ sequencer achieved over 99.9% coverage in sequencing samples from four Chikungunya virus patients, successfully distinguishing between African and Asian strains [2] - The T1+ sequencer can produce Tb-level data within 24 hours and has a rapid sequencing time of 7 hours for SE50 sequencing, significantly enhancing epidemic response efficiency [2] Group 3 - The CycloneSEQ platform, utilizing nanopore technology, provides real-time and portable sequencing capabilities, achieving 100% genome coverage in just 20 minutes, matching traditional high-throughput sequencing results [3] - In 2024, 37 gene sequencers received NMPA approval for clinical testing, with 23 based on BGI Genomics' DNBSEQ technology, representing 62% of the total approved devices in China [3] Group 4 - BGI Genomics has sold over 4,500 gene sequencers globally, capturing approximately 28.2% of the new sales market share, a significant increase of 9.5 percentage points from 2023 [3] - The company is expanding its business beyond core sequencing instruments to include biobanks, cell genomics, and spatial omics, while also exploring applications in judicial and animal disease fields [3] Group 5 - The surge in demand across clinical, agricultural, disease control, and customs sectors, combined with rapid growth in multi-omics business and increasing installation of core sequencers, provides a solid growth driver for BGI Genomics' future performance [4] - As the only company globally with both large-scale commercial short-read (DNBSEQ) and long-read (CycloneSEQ) sequencing products, BGI Genomics is positioned to expand its market share in life science tools and offer diverse solutions for pathogen monitoring and public health safety [4]

Group 1 - The Shanghai Stock Exchange Sci-Tech Innovation Board Biopharmaceutical Index (000683) increased by 0.73% as of July 28, 2025, with notable gains from companies such as Junshi Biosciences (688180) up 3.74% and Zai Lab (688266) up 3.30% [1] - The recent outbreak of Chikungunya fever in Guangdong Province has led to nearly 3,000 new local cases, primarily concentrated in Foshan and Guangzhou, with a cumulative total exceeding 4,800 confirmed cases [1] - The Sci-Tech Biopharmaceutical ETF (588250) rose by 0.82%, with the latest price reported at 1.23 yuan [1] Group 2 - Short-term focus on beneficiaries of the Chikungunya fever outbreak includes the vaccine sector, which may see valuation recovery due to market sentiment stabilizing despite anticipated performance pressure in 2024 [2] - The pharmacy sector is adapting to changes in medical insurance and regulatory environments, with companies like Yao Yi Tang exploring new business models, such as health and beauty products, to enhance profitability [2] - The diagnostics sector may experience renewed demand due to the Chikungunya fever, following the normalization of COVID-19 related demand [2] Group 3 - As of June 30, 2025, the top ten weighted stocks in the Shanghai Stock Exchange Sci-Tech Innovation Board Biopharmaceutical Index accounted for 50.3% of the index, including companies like United Imaging Healthcare (688271) and BeiGene (688235) [3]

Core Viewpoint - The article highlights the strong performance and liquidity of the Science and Technology Innovation (Sci-Tech) Pharmaceutical ETF managed by Harvest, indicating significant growth in both trading volume and fund shares over the past year [2][4]. Group 1: Liquidity and Trading Performance - The Sci-Tech Pharmaceutical ETF by Harvest recorded a turnover rate of 15.19% during trading, with a transaction volume of 30.598 million yuan, reflecting active market participation [2]. - As of July 25, the average daily trading volume over the past week was 46.0799 million yuan, ranking first among comparable funds [2]. - The fund's shares increased by 67.5 million over the past year, also ranking first among comparable funds [2]. Group 2: Fund Performance and Returns - The net value of the Sci-Tech Pharmaceutical ETF increased by 52.17% over the past year, placing it in the top 16.41% among 2,938 index equity funds [2]. - Since its inception, the fund achieved a maximum monthly return of 23.29%, with the longest consecutive monthly gains lasting 5 months and a maximum cumulative increase of 23.50% [2]. - The average return during the months of increase was 7.43% [2]. Group 3: Key Holdings and Market Outlook - As of June 30, 2025, the top ten weighted stocks in the Shanghai Stock Exchange Sci-Tech Innovation Board Biopharmaceutical Index accounted for 50.3% of the index, with leading companies including United Imaging Healthcare, BeiGene, and Huatai Medical [2][4]. - Based on the current fundamentals of the pharmaceutical sector, which has undergone four years of adjustment, the market outlook suggests a positive trend for innovative drugs and the overall pharmaceutical sector [4][5]. - The recommendation is to focus on innovative drugs as the primary investment theme, while also considering sectors like CRO&CDMO and specialty raw materials that are expected to perform well [5].

Group 1 - The World Health Organization (WHO) experts issued a warning on July 22 regarding the chikungunya virus, urging countries to prepare for potential outbreaks and emphasizing the importance of mosquito control and source identification [1] - The Shenzhen CDC and BGI Genomics collaborated using the DNBSEQ T1+ sequencing platform to trace the chikungunya virus in infected individuals, achieving over 99.9% coverage in sequencing [1] - The T1+ sequencing instrument supports rapid and precise virus tracing, enabling public health authorities to develop effective control strategies [1] Group 2 - The T1+ is recognized as the fastest desktop Tb-level sequencer globally, capable of producing complete genomes from low-load, diverse virus samples without the need for culture [2] - It can generate Tb-level data within 24 hours and features automated operations, integrating sequencing and bioinformatics analysis into a closed-loop process [2] - The T1+ provides a comprehensive automated workflow for infectious disease control, meeting the core demands of public health for precision, speed, and simplicity [2] Group 3 - Multiple customs authorities are utilizing the CycloneSEQ platform for full genome sequencing of the chikungunya virus to control imported cases [3] - The CycloneSEQ platform achieves 100% coverage in sequencing results, matching those obtained from the DNBSEQ platform, and offers real-time monitoring of high-density samples at entry points [3] - BGI Genomics is the only company globally to offer both short-read (DNBSEQ) and long-read (CycloneSEQ) sequencing products, catering to diverse monitoring and control needs for pathogenic microorganisms [3]

Group 1: ETF Performance - The liquidity of the Kexin Pharmaceutical ETF managed by Jiashi showed a turnover rate of 16.97% with a transaction volume of 33.88 million yuan, indicating active market trading [2] - Over the past year, the Kexin Pharmaceutical ETF has seen a significant growth in scale, increasing by 119 million yuan, ranking first among comparable funds [2] - The net asset value of the Kexin Pharmaceutical ETF has risen by 48.37% over the past year, placing it in the top 15.05% among index equity funds [2] Group 2: Stock Performance - The top ten weighted stocks in the Shanghai Stock Exchange Science and Technology Innovation Board Biopharmaceutical Index account for 50.3% of the index, with leading stocks including United Imaging Healthcare and BeiGene [2] - Recent stock performance includes United Imaging Healthcare with a rise of 2.04% and BeiGene with a slight increase of 0.21%, while Huatai Medical saw a decline of 2.71% [4] Group 3: Industry Trends - The biopharmaceutical industry is entering a dual-driven phase of policy and technology, with innovation drug support policies advancing to phase 2.0 [5] - The medical device sector is experiencing a core trend of replacement and technology export, with regulatory upgrades promoting innovation and industry breakthroughs [5] - State-owned capital entering the biopharmaceutical sector is injecting financial vitality, accelerating R&D investment and industry chain integration [5] Group 4: Licensing Agreements - Chinese innovative pharmaceutical companies are reporting significant "Licence Out" transactions, with Kexin Pharmaceuticals announcing a deal with ERIGEN for an exclusive overseas licensing agreement worth up to 1.32 billion USD [4]

Group 1: ETF Performance - The liquidity of the Kexin Pharmaceutical ETF (嘉实) showed an intraday turnover of 18.19%, with a transaction volume of 40.9491 million yuan, indicating active market trading [3] - Over the past week, the Kexin Pharmaceutical ETF (嘉实) experienced a scale increase of 16.9597 million yuan, ranking first among comparable funds [3] - The Kexin Pharmaceutical ETF (嘉实) saw a share increase of 7.5 million shares over the past week, also ranking first among comparable funds [3] - As of July 21, the Kexin Pharmaceutical ETF (嘉实) has achieved a net value increase of 43.45% over the past year, placing it in the top 16.56% among 2,929 index equity funds [3] Group 2: Stock Performance - The top ten weighted stocks in the Shanghai Stock Exchange Science and Technology Innovation Board Biopharmaceutical Index account for 50.3% of the index, with leading stocks including 联影医疗 (9.73%), 百济神州 (6.04%), and 惠泰医疗 (5.69%) [5][3] - The highest monthly return since inception for the Kexin Pharmaceutical ETF (嘉实) was 23.29%, with the longest consecutive monthly increase being 5 months and an average monthly return of 7.43% [3] Group 3: Market Trends - Huazhong Securities maintains a bottom-up view of the pharmaceutical sector, emphasizing the importance of hard technology innovations, particularly in innovative drugs and devices, which are becoming market hotspots [6] - The recent announcement from the Shanghai Sunshine Pharmaceutical Procurement Network regarding the 11th batch of national centralized procurement includes 55 drug varieties, with key principles focusing on stability, quality assurance, and anti-competitive practices [5]

证券代码：688114 证券简称：华大智造 公告编号：2025-046 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 深圳华大智造科技股份有限公司（以下简称"公司"）于 2025 年 6 月 8 日 召开第二届董事会第十四次会议，审议通过了《关于聘任董事会秘书的议案》， 董事会同意聘任彭欢欢女士为公司董事会秘书，任期自董事会审议通过之日起至 第二届董事会任期届满之日止。由于彭欢欢女士获聘时尚未取得上海证券交易所 颁发的科创板董事会秘书任职培训证明，暂由董事、总经理牟峰先生代行董事会 秘书职责。具体内容详见公司于 2025 年 6 月 9 日在上海证券交易所网站 （www.sse.com.cn）披露的《关于聘任董事会秘书以及补选第二届董事会非独立 董事的公告》（公告编号：2025-035）。 彭欢欢女士近期已参加上海证券交易所科创板上市公司董事会秘书任职培 训并完成测试，取得了董事会秘书任职培训证明。彭欢欢女士的董事会秘书任职 资格已在上海证券交易所备案。彭欢欢女士自取得科创板上市公司董事会秘书任 职培训证明之日起正式履行 ...

Group 1 - The third China International Supply Chain Promotion Expo showcased innovative health testing products, including gene testing for alcohol sensitivity and real-time ultrasound checks [1][2] - BGI Group introduced a proprietary "micro-sequencing" technology aimed at making gene testing as accessible as blood glucose and blood pressure monitoring, allowing for quick alcohol metabolism capability assessments [1][3] - The mini-sequencer and portable ultrasound device are designed to make advanced medical technology more accessible, with applications in public health and personalized healthcare solutions [2][3] Group 2 - BGI Genomics, as a leading company in the gene sequencing equipment sector in China, has over 3,300 users across research and clinical fields, contributing to daily scientific advancements [3] - The company emphasizes the importance of collaboration and resilience in advancing life sciences and health technology applications, aiming to establish industry standards and an open ecosystem [3]

Core Viewpoint - The AI Fund Zhaoshang Frontier Healthcare Stock A (011373) reported a profit of 41.645 million yuan for Q2 2025, with a fund net value growth rate of 7.89% and a total fund size of 570 million yuan as of the end of Q2 2025 [2][12]. Fund Performance - The fund's weighted average profit per share for the reporting period was 0.0404 yuan [2]. - As of July 17, the unit net value was 0.625 yuan [2]. - The fund's performance over various time frames includes a 32.00% growth rate over the last three months, 43.06% over the last six months, and 42.96% over the last year, ranking 22/54 and 21/53 among comparable funds respectively [2]. Fund Management - The fund is managed by Li Jiasun, who oversees four funds, all of which have shown positive returns over the past year [2]. - The fund focuses on sectors with a comparative advantage in certain growth, particularly in innovative drugs, R&D outsourcing, medical devices, and AI healthcare [2]. Risk Metrics - The fund's three-year Sharpe ratio stands at -0.1027, ranking 28/46 among comparable funds [7]. - The maximum drawdown over the last three years was 48.11%, with the largest single-quarter drawdown occurring in Q3 2022 at 26.38% [8]. Investment Strategy - The fund maintains a high stock position, averaging 90.79% over the last three years, with a peak of 94.27% at the end of Q3 2024 [11]. - The fund has a high concentration in its top ten holdings, which have consistently exceeded 60% over the past two years [15].