重要内容提示： 一、股票交易异常波动的具体情况 证券代码：688222 证券简称：成都先导 公告编号：2025-028 成都先导药物开发股份有限公司 股票交易异常波动公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或 者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 公司股票交易连续 3 个交易日内（2025 年 7 月 17 日、2025 年 7 月 18 日和 2025 年 7 月 21 日）收盘价格涨幅偏离值累计达到 30%，根据《上海证券交易所交易规 则》、《上海证券交易所科创板股票异常交易实时监控细则》的有关规定，属于股票 交易异常波动。 二、公司关注并核实的相关情况 1 成都先导药物开发股份有限公司（以下简称"公司"）股票交易连续三个交易 日内（2025 年 7 月 17 日、2025 年 7 月 18 日和 2025 年 7 月 21 日）收盘价格 涨幅偏离值累计达到 30%，根据《上海证券交易所交易规则》、《上海证券交易 所科创板股票异常交易实时监控细则》的有关规定，属于股票交易异常波动。 经公司自查，并发函问询控股股东、实际控制人，确认截至本公告披露日 ...

成都先导公告，公司股票交易连续三个交易日内(2025年7月17日、2025年7月18日和2025年7月21日)收 盘价格涨幅偏离值累计达到30%，属于股票交易异常波动。目前公司自主研发新药项目多数处于临床前 的不同阶段，开发具有很大的不确定性，后续是否能够实现对外转让存在重大不确定性。 ...

Group 1 - The CRO concept index rose by 2.61%, ranking 10th among concept sectors, with 55 stocks increasing in value, including Chengdu Xian Dao which hit a 20% limit up [1] - Leading gainers in the CRO sector included MediWest, Haitai Biological, and Boji Pharmaceutical, with increases of 19.00%, 11.93%, and 9.50% respectively [1] - The sector saw a net inflow of 447 million yuan from main funds, with 30 stocks receiving net inflows, and 8 stocks exceeding 50 million yuan in net inflow [2] Group 2 - Major contributors to net inflow included WuXi AppTec with 203 million yuan, followed by Zhaoyan New Drug, Chengdu Xian Dao, and MediWest with net inflows of 130 million yuan, 126 million yuan, and 107 million yuan respectively [2] - The net inflow ratios for Zhaoyan New Drug, Chengdu Xian Dao, and MediWest were 13.04%, 12.33%, and 11.88% respectively [3] - The trading volume for WuXi AppTec was 20.33 million yuan with a turnover rate of 1.67% [3] Group 3 - The stock Boji Pharmaceutical had a significant increase of 9.50% with a trading volume of 21.40 million yuan [6] - The stock ST Unnamed experienced the largest decline of 5.01% with a trading volume of 96.79 million yuan [6] - The overall performance of the CRO sector indicates strong investor interest and potential growth opportunities within the industry [2][3]

Market Performance - The recombinant protein concept increased by 2.92%, ranking 7th among concept sectors, with 43 stocks rising, including Chengdu Xian Dao and Mai Wei Bio reaching a 20% limit up [1] - Leading gainers included Shen Zhou Cell, Hai Te Bio, and Ke Xing Pharmaceutical, with increases of 15.40%, 11.93%, and 10.14% respectively [1] - Decliners included ST Wei Ming, *ST Su Wu, and Lizu Group, with decreases of 5.01%, 4.81%, and 0.49% respectively [1] Capital Flow - The recombinant protein sector saw a net inflow of 188 million yuan, with 17 stocks receiving net inflows, and 5 stocks exceeding 30 million yuan in net inflow [1] - Shen Zhou Cell led with a net inflow of 217 million yuan, followed by Chengdu Xian Dao, Mai Wei Bio, and Hui Yu Pharmaceutical with net inflows of 126 million yuan, 96.87 million yuan, and 45.41 million yuan respectively [1] Capital Inflow Ratios - Leading stocks in capital inflow ratios included Shen Zhou Cell, Chengdu Xian Dao, and Cheng Da Bio, with net inflow ratios of 16.25%, 12.33%, and 10.79% respectively [2] - The top stocks in the recombinant protein concept based on capital flow included Shen Zhou Cell, Chengdu Xian Dao, and Mai Wei Bio, with respective daily turnover rates of 3.70%, 12.33%, and 17.80% [2]

Core Viewpoint - The innovative drug sector is experiencing a significant surge in stock prices, driven by positive news and market momentum, with both A-shares and Hong Kong stocks showing substantial gains in related companies [1][2][3]. Group 1: Market Performance - On July 17, A-shares saw a collective rise, with the Shanghai Composite Index up by 0.37%, the Shenzhen Component up by 1.43%, and the ChiNext Index up by 1.76% [1]. - The innovative drug sector led the market, with nearly 20 related stocks hitting the daily limit or rising over 10%, including Chengdu XianDai, Saily Medical, and Lisheng Pharmaceutical [1][3]. Group 2: Positive News and Developments - A recent report indicated that the innovative drug "Qiruisuo Wei," developed in China for treating respiratory syncytial virus, has been included in the World Health Organization's priority list for children's medications, potentially providing accessible and affordable treatment for children globally [4][5][6]. - The WHO's initiative aims to accelerate the development of urgently needed children's medications, highlighting the critical need for effective treatments for respiratory syncytial virus, which causes millions of infections and significant mortality among young children each year [5]. Group 3: Policy Support - The National Healthcare Security Administration and the National Health Commission have issued measures to support the high-quality development of innovative drugs, including increasing support for R&D, facilitating access to insurance coverage, and enhancing clinical application [8]. - The introduction of a commercial health insurance directory for innovative drugs marks a significant step in expanding the role of commercial insurance in the multi-tiered healthcare system, providing more opportunities for high-priced innovative drugs [9][10]. Group 4: Industry Outlook - Analysts predict that the domestic innovative drug industry may reach a turning point in 2025, shifting from capital-driven growth to profit-driven growth, presenting opportunities for both performance and valuation recovery [11]. - China's share in global innovative drug business development transactions is expected to increase significantly, with a notable rise in the number and value of projects, particularly in areas like ADC and bispecific antibodies [12].

Market Overview - The A-share market showed a strong performance on July 17, with the Shanghai Composite Index rising by 0.37% and the Shenzhen Component Index increasing by 1.43% [1][2] - The total trading volume reached 1.56 trillion yuan, an increase of 98.5 billion yuan compared to the previous trading day, with over 3,500 stocks rising [1] Sector Performance - The CPO concept stocks performed strongly, with notable gains from companies like Shengyi Technology and Changfei Optical Fiber, which hit the daily limit [4][5] - The pharmaceutical sector also saw significant gains, with stocks such as Chengdu Xian Dao and Xin Li Tai reaching their daily limit [6][7] - The military industry stocks were active, with AVIC Shenfei reaching a historical high [6] - The steel sector experienced a rally, with Liugang Co. and Linggang Co. hitting the daily limit, while other steel stocks also showed positive performance [8] Notable Stocks - In the CPO sector, Shengyi Technology rose by 13.86%, while Shijia Photon increased by 11.10% [5] - In the military sector, AVIC Shenfei and other companies saw gains exceeding 6% [6] - The innovative drug sector had a surge, with Chengdu Xian Dao and Maiwei Biotech both hitting the daily limit [7] - In the steel sector, Liugang Co. rose by 10.08%, and Linggang Co. increased by 5.32% [8] Financial Sector - The financial sector, including banks and insurance companies, showed weakness, with *ST Tianmao dropping over 5% and several banks declining by more than 1% [12][13] Precious Metals and Real Estate - The precious metals sector experienced low volatility, with Shandong Gold falling over 2% [9][10] - The real estate sector faced adjustments, with companies like Zhongxin Group dropping over 6% [11] Future Outlook - According to research from China International Capital Corporation, the financial data indicates that market conditions are improving, and the current market point is significantly higher than the average cost over the past year and three years, suggesting a better profit outlook [14]

Market Overview - The A-share market experienced a rebound on July 17, with the Shanghai Composite Index fluctuating around the 3500-point mark, and the ChiNext Index showing stronger performance. The market saw nearly 3500 stocks in the green, with a total trading volume of 1.5 trillion yuan, an increase of 973.3 billion yuan compared to the previous trading day. The Shanghai Composite Index rose by 0.37%, the Shenzhen Component Index increased by 1.43%, and the ChiNext Index gained 1.76% [1][2]. Reasons for Index Rebound - The rebound in the index is attributed to three main factors: 1. China released better-than-expected economic data, prompting foreign institutions like Morgan Stanley, Goldman Sachs, and UBS to raise their GDP growth forecasts for China in 2025. 2. Positive signals emerged from US-China trade relations, with significant changes in US export policies for AI chips, including the resumption of sales of Nvidia's H20 chip and AMD's plans to restore exports of MI308 chips to China. 3. The ongoing strong performance of mid-year reports, particularly in the computing power and innovative pharmaceuticals sectors, with many companies in these areas reporting positive earnings forecasts [2]. Hot Sectors 1. **Computing Power Hardware Sector** - The computing power hardware sector saw a collective surge, with PCB and CPO sectors leading the gains. Stocks like Cambridge Technology and Dongshan Precision hit the daily limit, while others like Xinyisheng and Shenghong Technology reached new highs. The positive sentiment is driven by recent earnings forecasts and Nvidia's resumption of H20 chip sales to China, which is expected to boost investment opportunities in the industry chain [4][5]. 2. **Innovative Pharmaceuticals Sector** - The innovative pharmaceuticals sector continued its strong performance, with stocks such as Weikang Pharmaceutical and Chengdu Xian Dao hitting the daily limit. The sector's strength is attributed to a series of favorable policy releases and consistent earnings growth among several companies, indicating a high level of industry prosperity. The National Medical Insurance Bureau's push for payment reform is expected to provide more opportunities for high-priced innovative drugs and medical devices [6][7]. 3. **Robotics Sector** - The robotics sector experienced renewed strength, with stocks like Zhongdali De achieving significant gains. The momentum is supported by Nvidia's CEO highlighting the upcoming wave of AI in robotics at a recent conference, indicating a pivotal moment for the commercialization of humanoid robots [8][9]. Institutional Perspectives 1. **Ping An Securities** - Ping An Securities suggests that while there are external uncertainties, domestic policy support and positive changes in industrial upgrades are likely to sustain a strong market trend. They recommend focusing on three main lines: technology growth sectors, industries benefiting from "anti-involution" policies, and financial sectors with high dividend advantages [10]. 2. **Caixin Securities** - Caixin Securities notes that the market is entering a new bullish phase, with no significant macro risks expected before August. They anticipate continued upward momentum in the index, supported by improved investor sentiment and increased capital inflow [11]. 3. **Huaxi Securities** - Huaxi Securities highlights a recovery in market risk appetite, driven by the return of financing and capital inflows. They believe that while the market may experience some consolidation, the long-term outlook remains positive due to ongoing policy support for the capital market [12].

Group 1 - The A-share CRO (Contract Research Organization) sector experienced a significant rally in the afternoon, with notable stocks such as Chengdu Xian Dao hitting the daily limit up [1] - MediXy and Hite Bio both surged over 14%, indicating strong investor interest and market momentum [1] - Other companies in the sector, including Zhaoyan New Drug, Yinuosi, Sunshine Nuohe, Kanglong Huacheng, and Puris, also saw positive gains, reflecting a broader trend in the CRO market [1]

Group 1: Stock Performance - Zhejiang Zhenyuan and Asia-Pacific Pharmaceutical both achieved a 2-day limit-up with increases of 10.01% and 9.98% respectively, driven by innovation in pharmaceuticals [2] - Chengdu XianDao saw a first board listing with a significant rise of 20.02%, attributed to innovative drug developments [2] - TaiJing Technology and YanHua Intelligent both recorded first board listings with increases of 9.97% and 9.94%, linked to Huawei's influence in robotics [5] Group 2: AI and Robotics - Nvidia's CEO suggested that Huawei's AI chips could potentially replace Nvidia's offerings, indicating a competitive shift in the AI chip market [4] - The domestic robotics industry is gaining traction with significant orders being awarded, highlighting its importance in national competition [7] Group 3: Market Trends - The light communication sector is expected to see sustained growth due to high demand in both domestic and international markets, with performance likely to continue improving [13] - The low-altitude economy is gaining attention, with a notable $1 billion procurement agreement signed for eVTOL aircraft, indicating growth potential in this sector [17] Group 4: Consumer and Retail - The Chinese government is implementing measures to boost consumer spending, which is expected to positively impact the retail sector [21] - Companies like Guoguang Chain and Hanshang Group have seen first board listings with increases of 9.98% and 9.97%, reflecting the positive sentiment in the retail market [23] Group 5: Solar and Food & Beverage - The price of polysilicon has increased by 12.4% week-on-week, indicating a rising trend in the solar industry [24] - The food and beverage sector is also benefiting from government initiatives aimed at enhancing consumer demand, with companies like Huangshi Group seeing a 10.10% increase [26]

Market Overview - The A-share market opened slightly lower on July 17 but then experienced a rebound, with all three major indices showing positive performance, particularly the ChiNext index which rose nearly 1% [2] - The total market capitalization reached 14.20 trillion CNY, with a trading volume of 7698.06 million hands and a turnover rate of 1.46% [3] Pharmaceutical Sector - The pharmaceutical sector saw a significant surge, with multiple stocks hitting the daily limit up, including Weikang Pharmaceutical and Chengdu Xian Dao, both reaching a 20% increase [4][5] - Notable stocks in the pharmaceutical sector included: - Chengdu Xian Dao: 21.46 CNY, up 20.02% - Weikang Pharmaceutical: 20.71 CNY, up 19.99% - Other stocks like Lifespring Pharmaceutical and Zhejiang Zhenyuan also saw increases of around 10% [5][6] - The Hong Kong pharmaceutical and biotechnology sector also experienced notable gains, with companies like Fudan Zhangjiang and Kanyin Biotech showing significant price increases [6] Robotics Sector - The humanoid robot concept stocks remained active, with Nanjing Julong hitting the daily limit up of 20%, and other companies like Dongshan Precision and Taijing Technology also seeing substantial gains [7][8] - On July 17, the stock of Aowei New Materials achieved a 20% limit up, marking its seventh consecutive trading day of gains, with a closing price of 27.89 CNY [10][11] Policy Impact - The National Healthcare Security Administration recently announced the initiation of the 11th batch of centralized drug procurement, which will include 55 drug varieties, focusing on mature "old drugs" while excluding innovative drugs from the procurement list [6]