证券代码：688363 证券简称：华熙生物 公告编号：2025-009 华熙生物科技股份有限公司 关于预计2025年度日常关联交易公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 重要内容提示： 一、 日常关联交易基本情况 (一) 日常关联交易履行的审议程序 | 关联交 易类别 | 关联人 | 本次预计金 | 占同类业 务比例 | 本年年初至 披露日与关 联人累计已 | 上年实际发 | 占同类 业务比 | 本次预 计金额 与上年 实际发 | | --- | --- | --- | --- | --- | --- | --- | --- | | | | 额 | （%） | 发生的交易 金额 | 生金额 | 例（％） | 生金额 差异较 大的原 | | | | | | | | | 因 | | | 小计 | 10,200,000.00 | 0.19% | 50,538.94 | 2,072,197.31 | 0.04% | | | | 中国人寿保险股 | 4,000,000.00 | 42.16% | 30,188.68 | ...

证券代码：688363 证券简称：华熙生物 公告编号：2025-007 华熙生物科技股份有限公司 第二届监事会第十二次会议决议公告 本公司监事会及全体监事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 一、监事会会议召开情况 2025 年 4 月 9 日华熙生物科技股份有限公司（以下简称"公司"）以现场会 议结合通讯方式召开了第二届监事会第十二次会议，会议通知已于 2025 年 3 月 30 日以电子邮件形式发出。本次会议由监事会主席于静女士主持，应出席监事 3 人，实际出席并表决的监事 3 人。会议的召开及程序符合《中华人民共和国公司 法》《公司章程》及公司《监事会议事规则》的相关规定。 二、监事会会议审议情况 (一) 审议通过《关于审议 2024 年度监事会工作报告的议案》 表决结果：同意 3 票，反对 0 票，弃权 0 票。 2024 年度，监事会按照《公司法》《证券法》《上海证券交易所科创板股票 上市规则》《上海证券交易所科创板上市公司自律监管指引第 1 号——规范运作》 《公司章程》及《监事会议事规则》等有关法律法规和规范性文件的要求 ...

证券代码：688363 证券简称：华熙生物 公告编号：2025-006 华熙生物科技股份有限公司 第二届董事会第十七次会议决议公告 公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或 者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 一、董事会会议召开情况 1 表决结果：9 票赞成，0 票弃权，0 票反对。 2025 年 4 月 9 日华熙生物科技股份有限公司（以下简称"公司"或"华熙生物"） 于公司会议室以现场会议结合通讯方式召开了第二届董事会第十七次会议，会议 通知已于 2025 年 3 月 30 日以电子邮件形式发出。本次会议由董事长赵燕女士 主持，应出席董事 9 人，实际出席董事 9 人，其中董事邹松岩先生委托董事樊媛 女士代为出席会议并行使表决权，公司监事及部分高级管理人员列席了本次董事 会。会议的召开及程序符合《中华人民共和国公司法》《公司章程》等相关法律 法规的规定。 二、董事会会议审议情况 (一) 审议通过《关于审议公司 2024 年年度报告及其摘要的议案》 表决结果：9 票赞成，0 票弃权，0 票反对。 本议案在呈交董事会审议前已经公司审计委员会审议通过。 具 ...

华熙生物科技股份有限公司 会议决议 华熙生物科技股份有限公司 第二届董事会独立董事专门会议 2025 年第一次会议决议 华熙生物科技股份有限公司第二届董事会独立董事专门会议 2025 年第一次会 议于 2025 年 3 月 28 日在华熙国际中心 D 座 33 层以现场结合通讯方式召开。会议 通知及会议资料于 2025 年 3 月 25 日以电子邮件方式送达各位独立董事。本次会 议应出席独立董事 3 名，实际出席并表决独立董事 3 名。此外，公司董事会秘书 李亦争先生、财务总监汪卉先生列席了本次会议。会议的召集、召开及表决程序 符合公司《独立董事专门会议工作细则》的规定。 经与会独立董事审议，会议通过了如下议案： 1. 《关于预计公司 2025 年度日常关联交易的议案》 表决结果：3 票赞成，0 票弃权，0 票反对。 回避表决情况：无。 （以下无正文） 华熙生物科技股份有限公司 会议决议 （本页无正文，为《华熙生物科技股份有限公司第二届董事会独立董事专门会议 2025 年第一次会议决议》签字页 委员签字： 陈关亭： 王颖千： 会议决议 （本页无正文,为《华熙生物科技股份有限公司第二届董事会独立董事专门会议 2 ...

本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 一、 利润分配预案内容 证券代码：688363 证券简称：华熙生物 公告编号：2025-008 华熙生物科技股份有限公司 2024 年年度利润分配预案公告 (一) 利润分配预案的具体内容 经致同会计师事务所（特殊普通合伙）审计，公司 2024 年度合并报表实现 归属于母公司股东的净利润 174,267,399.74 元，截至 2024 年 12 月 31 日，公司 母公司报表中期末未分配利润为 3,500,635,673.29 元。经董事会决议，公司 2024 年年度拟以实施权益分派股权登记日登记的总股本扣除公司回购专用证券账户 中股份数为基数分配利润。本次利润分配预案如下： 1 每股分配比例:每股派发现金红利 0.11 元（含税），不进行资本公积转增 股本，亦不派发红股 本次利润分配以实施权益分派股权登记日登记的总股本扣除公司回购 专用证券账户中股份数为基数，具体日期将在权益分派实施公告中明确。 若在实施权益分派的股权登记日前公司总股本扣除公司回购专用证券 账户 ...

Core Viewpoint - The article discusses the internal turmoil and strategic challenges faced by Huaxi Biological, particularly in light of its declining performance and the need for significant internal reforms to address corruption and strategic misalignment [3][4][5]. Group 1: Internal Challenges and Strategic Issues - Huaxi Biological's CEO Zhao Yan issued an ultimatum for employees involved in corruption to resign by March 31, indicating a critical need for internal restructuring [3]. - The company is experiencing a significant decline in revenue and profits, with a reported drop of over 70% in profits for 2024, highlighting the urgency of the situation [3][4]. - The internal issues are compounded by strategic missteps, particularly the failure to adapt to market changes and the overproduction of hyaluronic acid, leading to an oversupply situation [9][15]. Group 2: Market Dynamics and Competitive Landscape - The hyaluronic acid market has shifted from a scarcity to an oversupply, with average prices dropping from 210 RMB per gram in 2017 to 124 RMB in 2021, a decline of 41% [9]. - New competitors in the collagen market have emerged, capturing consumer interest and market share, which has further pressured Huaxi Biological's traditional hyaluronic acid business [11][12]. - The company has been slow to diversify into collagen products, missing out on a significant market opportunity that could have alleviated current pressures [12][15]. Group 3: Financial Performance and Cost Management - Huaxi Biological's sales and management expenses have surged from 38.23% in 2018 to 61.72% in 2023, with sales expenses alone increasing from 284 million RMB to 2.842 billion RMB during the same period [27]. - Despite maintaining a high gross margin of around 73%, the net profit margin has plummeted from 33.56% in 2018 to approximately 9.27% in 2024, indicating severe profitability issues [27][28]. - The company's strategy to cut costs and improve profitability through internal reforms may provide short-term relief, but long-term success will depend on genuine operational improvements [29][30].

证券代码：688363 证券简称：华熙生物 公告编号：2025-005 华熙生物科技股份有限公司 关于高级管理人员调整及聘任的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 2025 年 3 月 18 日，华熙生物科技股份有限公司（以下简称"公司"）召开第 二届董事会第十六次会议，审议通过《关于高级管理人员调整以及聘任的议案》。 公司正在进行管理变革，为调整管理架构，结合公司战略发展需要，根据《公司 法》《公司章程》等有关规定，经公司总经理提议，对部分高级管理人员职务进 行调整，同时根据公司经营管理需要，聘任新的高级管理人员，具体情况如下： 一、公司高级管理人员的调整 （一）刘爱华女士 鉴于刘爱华女士已超过法定退休年龄，退休时与公司签订了返聘合同，现该 返聘合同将于近期到期，且到期后不再续签。刘爱华女士不再担任副总经理职务， 后续将不再在公司担任任何职务。 （二）徐桂欣女士、栾依峥先生 公司正在进行管理变革，为调整管理架构、精简管理层级，公司决定减少非 法定要求的副总经理职位数量。徐桂欣女士与栾依峥先生不再担任副总经 ...

Investment Rating - The report recommends a "buy" rating for the cosmetics and medical beauty sectors, highlighting a favorable outlook for 2025 due to improved consumer expectations and policy support [4][6]. Core Insights - The report emphasizes that the cosmetics sector will focus on three key elements: domestic brands, segmentation, and cost-effectiveness, with a projected steady growth in demand for 2025 [4][6]. - The medical beauty industry is expected to benefit from improved income expectations, with domestic companies poised to become major competitors in the light medical beauty segment [4][6]. - E-commerce is identified as a growth area, with new consumption models and brands emerging to drive development [4][6]. Summary by Sections 1. Industry Performance Review - The beauty and personal care sector has not achieved excess returns in 2025 due to trading disruptions, but is expected to rebound with policy support [7][8]. - The SW beauty index has seen a growth of 0.6% since the beginning of 2025, underperforming compared to the broader A-share index [8][10]. 2. Cosmetics Sector - The report forecasts a recovery in the cosmetics demand in 2025, with a focus on high cost-performance brands benefiting from consumer preferences [15][18]. - Domestic brands are gaining market share, with significant growth in the skincare market, where domestic brands now occupy four out of the top ten positions [18][19]. - The report highlights the success of domestic brands in e-commerce platforms, particularly during promotional events, indicating a strong competitive position against international brands [21][22]. 3. Medical Beauty Sector - The medical beauty market is transitioning from a blue ocean to a red ocean, with domestic companies expanding their product lines and research pipelines [4][6]. - Key recommendations include focusing on companies with strong product pipelines and high profitability, such as Ai Meike [4][6]. 4. E-commerce Sector - The report suggests that the e-commerce sector will continue to thrive with the rise of new consumption models and brands, particularly benefiting from the growth of domestic brands [4][6]. 5. Key Company Recommendations - The report recommends several companies based on their brand matrix and growth potential, including Shangmei Co., Pulaile, and others in the cosmetics sector [4][6]. - In the medical beauty sector, Ai Meike is highlighted as a key player, with a focus on companies with strong product offerings and research capabilities [4][6].

Investment Rating - The industry investment rating is "Overweight" [1] Core Insights - The prospects for biomanufacturing are broad, contributing to industrial upgrades. Biomanufacturing, centered on industrial biotechnology, utilizes enzymes and microbial cells in the processing of target products, including bio-based materials, chemicals, and bioenergy. Synthetic biology plays a crucial role as a platform technology in biomanufacturing. The global synthetic biology market is expected to maintain rapid growth, reaching nearly $50 billion by 2028 [3][4][22]. - Technological breakthroughs combined with policy support are driving the synthetic biology industry forward. Factors such as reduced costs of gene synthesis and sequencing, along with advancements in efficient gene editing technologies, provide a solid technical foundation for the rapid development of synthetic biology. Governments worldwide are increasingly prioritizing the development of synthetic biology, with various supportive policies being introduced [4][28]. - Synthetic biology is reshaping industrial models, offering more efficient and environmentally friendly synthesis solutions. It addresses issues associated with traditional chemical synthesis and natural extraction methods, such as high costs, limited yields, and environmental pollution. With breakthroughs in gene editing, enzyme engineering, and metabolic engineering, synthetic biology not only reduces drug production costs but also enhances capacity, enabling large-scale industrial production [4][5]. Summary by Sections Industry Overview - Biomanufacturing is defined as the processing of target products using industrial biotechnology, involving enzymes and microbial cells. Synthetic biology is a key platform technology in this field, enabling the design and construction of biological systems for various applications [13][14]. Policy Support and Technological Breakthroughs - The development of synthetic biology is supported by various policies and technological advancements. Governments are investing in funding, technology, and talent development to foster innovation and industrialization in this field [28][29]. - Major countries are establishing synthetic biology research centers and networks, with the UK and the US leading in policy initiatives to promote synthetic biology [29][30]. Synthetic Biology's Impact on Industrial Models - Synthetic biology is transforming production methods, achieving tasks that traditional biotechnologies cannot, while providing more efficient and eco-friendly synthesis options. This shift is crucial for addressing environmental challenges and enhancing production efficiency [4][5]. Investment Recommendations - Companies to watch include Chuan Ning Biological, Kingfisher Biotech, Kylin Biotech, and Huaxi Biological, which are positioned to benefit from the growth in synthetic biology [5].