Core Viewpoint - A class action securities lawsuit has been filed against Novo Nordisk A/S due to alleged securities fraud affecting investors between November 2, 2022, and December 19, 2024 [1] Group 1: Lawsuit Details - The lawsuit aims to recover losses for investors impacted by the company's underperformance in the "REDEFINE 1" trial, which reported a weight loss of 22.7% after 68 weeks, falling short of the expected 25% [2] - Following the disappointing trial results, Novo's stock price dropped by $18.44, closing at $85.00 per share [2] Group 2: Next Steps for Investors - Investors who suffered losses during the specified timeframe have until March 25, 2025, to request appointment as lead plaintiff, although participation in any recovery does not require this role [3] - Class members may be eligible for compensation without incurring any out-of-pocket costs or fees [3] Group 3: Firm Background - Levi & Korsinsky has a history of securing significant settlements for shareholders and is recognized as one of the top securities litigation firms in the United States [4]

LOS ANGELES, Jan. 28, 2025 /PRNewswire/ -- The Schall Law Firm, a national shareholder rights litigation firm, reminds investors of a class action lawsuit against Novo Nordisk A/S ("Novo" or "the Company") (NYSE: NVO) for violations of §§10(b) and 20(a) of the Securities Exchange Act of 1934 and Rule 10b-5 promulgated thereunder by the U.S. Securities and Exchange Commission.Investors who purchased the Company's securities between November 02, 2022 and December 19, 2024, inclusive (the "Class Period"), are ...

SAN DIEGO, Jan. 27, 2025 /PRNewswire/ -- The law firm of Robbins Geller Rudman & Dowd LLP announces that purchasers or acquirers of Novo Nordisk A/S (NYSE: NVO) securities between November 2, 2022 and December 19, 2024, both dates inclusive (the "Class Period"), have until March 25, 2025 to seek appointment as lead plaintiff of the Novo Nordisk class action lawsuit.  Captioned Moon v. Novo Nordisk A/S, No. 25-cv-00713 (D.N.J.), the Novo Nordisk class action lawsuit charges Novo Nordisk and certain of Novo N ...

SAN DIEGO, Jan. 27, 2025 /PRNewswire/ -- Robbins LLP informs stockholders that a class action was filed on behalf of all investors who purchased or otherwise acquired Novo Nordisk A/S (NYSE: NVO) securities between November 2, 2022 and December 19, 2024. Novo is a healthcare company, focused on the research, development, manufacturing, and distribution of pharmaceutical productions globally.For more information, submit a form, email attorney Aaron Dumas, Jr., or give us a call at (800) 350-6003.The Allegati ...

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Core Insights - Novo Nordisk has reported promising results from a phase 1b/2a clinical trial of amycretin, a new GLP-1 and amylin receptor agonist, which has led to a positive market reaction with a 7.7% increase in stock price [2][4] - The trial showed a 9.7% average reduction in body weight over 36 weeks, with mild to moderate gastrointestinal side effects reported [3][4] - The company plans to further develop amycretin based on these encouraging results, despite it being an early-stage trial [4] Company Performance - The stock price of Novo Nordisk increased by 7.7% following the announcement of the trial results [2] - Novo Nordisk's current P/E ratio is 27.4, which is significantly lower than its closest competitor, Eli Lilly, suggesting it may be undervalued in the weight-loss drug market [4] Clinical Trial Details - The amycretin trial was conducted over 36 weeks with doses ranging from 1.25 mg to 20 mg [3] - The weight loss achieved in this trial is approximately half of that seen in previous studies of semaglutide, but achieved in a shorter time frame [4]

Core Insights - Novo Nordisk's U.S.-listed shares surged 9% following the announcement of early-stage results for its amycretin weight-loss drug [2][5] - The Phase 1b/2a clinical trial demonstrated significant weight loss in participants, with the highest dosage of 20mg resulting in a 22% reduction in body weight after 36 weeks, while placebo participants gained 2% [3][4] - The company plans further clinical development of amycretin for adults with overweight or obesity, indicating a positive outlook on the drug's potential [4] Company Performance - Prior to the announcement, Novo Nordisk's shares had been trending lower, with an 18% drop in one day last month due to disappointing results from another weight-loss drug, CagriSema [4] - Over the past 12 months, Novo Nordisk's shares fell approximately 23%, reflecting challenges in the weight-loss drug market amid increasing competition [5] - In contrast, Eli Lilly, a competitor in the weight-loss drug market, saw its shares increase by about 20% over the same period, despite a 1% dip following the news [5]

Company Performance - Shares of Novo Nordisk jumped 9 5% at 11 02 a m London time following positive early-stage results for its once weekly amycretin obesity drug [1] - The trial showed an average weight reduction of 22% in obese and overweight patients after 36 weeks [1] Product Development - Novo Nordisk reported positive early-stage results for its once weekly amycretin obesity drug [1] - The drug demonstrated significant efficacy with a 22% average weight reduction in obese and overweight patients over 36 weeks [1]

Clinical Trial Results - Novo Nordisk announced topline results from a phase 1b/2a clinical trial for amycretin, a unimolecular GLP-1 and amylin receptor agonist intended for once-weekly subcutaneous administration [1] - The trial involved 125 people with overweight or obesity and investigated safety, tolerability, pharmacokinetics, and proof-of-concept over up to 36 weeks of treatment [2] - The primary endpoint was treatment-emergent adverse events, with the safety profile consistent with incretin-based therapies and most adverse events being mild to moderate gastrointestinal issues [3] Efficacy Data - Participants treated with amycretin achieved estimated body weight loss of 9.7% on 1.25mg (20 weeks), 16.2% on 5mg (28 weeks), and 22.0% on 20mg (36 weeks) from a mean baseline body weight of 92.7 kg [4] - Placebo-treated participants experienced estimated body weight gains of 1.9%, 2.3%, and 2.0% respectively [4] Company Commentary - Novo Nordisk expressed encouragement with the trial results, highlighting the weight-lowering potential of amycretin and its alignment with previous oral formulation results [5] - The company plans further clinical development of amycretin for adults with overweight or obesity [5] Product Background - Amycretin is a unimolecular long-acting GLP-1 and amylin receptor agonist under development for both oral and subcutaneous administration, targeting overweight, obesity, and type 2 diabetes [6] Trial Design - The phase 1b/2a trial was a randomised, placebo-controlled, double-blinded study conducted in five parts, exploring pharmacokinetics, safety, tolerability, and proof-of-concept over up to 36 weeks with dose escalation [7] Company Overview - Novo Nordisk is a global healthcare company founded in 1923, headquartered in Denmark, with a focus on defeating serious chronic diseases through scientific breakthroughs and expanding access to medicines [8] - The company employs approximately 72,000 people in 80 countries and markets products in around 170 countries [8]

Core Viewpoint - Novo Nordisk's shares declined by 5.3% following Medicare's announcement of including its semaglutide medicines in the second round of price negotiations for 2025, raising concerns about potential profit margin reductions [1][2]. Group 1: Medicare Negotiations Impact - Medicare has selected Novo Nordisk's semaglutide medicines for price negotiations, which will take effect in 2027, with a decision deadline for the company set for February 28, 2025 [2]. - The Inflation Reduction Act enables Medicare to negotiate prices for certain prescription drugs, aiming to make them more affordable for seniors and individuals with disabilities [2]. - Approximately 5.3 million Medicare Part D beneficiaries used the selected drugs, which accounted for around $41 billion, or 14%, of total gross covered prescription drug costs under Medicare Part D from November 2023 to October 2024 [3]. Group 2: Stock Performance and Industry Comparison - In the past three months, Novo Nordisk's shares have decreased by 32.9%, while the industry average decline was 16.6% [3]. - Eli Lilly, a competitor in the obesity market, also saw a 4.2% decline in its stock, despite none of its drugs being selected for negotiations, indicating investor concerns about future selections [4]. Group 3: Clinical Study Results - Novo Nordisk announced positive topline data from a late-stage study of semaglutide 7.2 mg, showing superior weight loss compared to Wegovy and placebo [7][8]. - Patients starting with a mean baseline weight of 113 kg experienced a weight loss of 20.7% after 72 weeks with semaglutide 7.2 mg, compared to 17.5% with Wegovy and 2.4% with placebo [9]. - The candidate demonstrated a safe profile, with adverse events mostly mild to moderate, consistent with the GLP-1 receptor agonist class [10]. Group 4: Future Expectations - Novo Nordisk plans to present detailed results from the phase IIIb STEP UP study at a medical conference in 2025 and expects to share results from another phase III study for T2D and obesity in the coming months [11].