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Addex GABAB PAM Candidate Demonstrates Robust Anti-Tussive Activity in Multiple Chronic Cough Preclinical Models
GlobeNewswire News Room· 2025-06-06 05:00
Ad Hoc Announcement Pursuant to Art. 53 LR  Geneva, Switzerland, June 6, 2025 - Addex Therapeutics (SIX: ADXN and Nasdaq: ADXN), a clinical-stage biopharmaceutical company focused on developing a portfolio of novel small molecule allosteric modulators for neurological disorders, announced today robust anti-tussive activity of its novel gamma-aminobutyric acid sub-type B receptor (GABAB) positive allosteric modulator (PAM) in multiple preclinical models of chronic cough compared to reference drugs. Some of ...
Reasons to Add Pampa Energia Stock to Your Portfolio Right Away
ZACKS· 2025-05-21 12:26
Pampa Energia S.A. (PAM) benefits from its focus on maintaining asset quality and expanding its generation portfolio. The company also gains from its efforts to expand its operations in the generation, transmission and distribution of electricity in Argentina. Given its strong growth, PAM makes for a solid investment option in the utility sector.Let’s focus on the factors that make this Zacks Rank #2 (Buy) company a strong investment option at the moment.PAM’s Growth Projections & Surprise HistoryThe Zacks ...
All You Need to Know About Pampa (PAM) Rating Upgrade to Strong Buy
ZACKS· 2025-04-22 17:00
Pampa Energia (PAM) could be a solid addition to your portfolio given its recent upgrade to a Zacks Rank #1 (Strong Buy). This rating change essentially reflects an upward trend in earnings estimates -- one of the most powerful forces impacting stock prices.A company's changing earnings picture is at the core of the Zacks rating. The system tracks the Zacks Consensus Estimate -- the consensus measure of EPS estimates from the sell-side analysts covering the stock -- for the current and following years.Since ...
Pampa Energia(PAM) - 2024 Q4 - Annual Report
2025-04-16 15:46
Production and Reserves - As of December 31, 2024, the company has a total production of 78.2 thousand boe/d, with crude oil production at 4.8 k bbl/d and natural gas production at 73.4 thousand boe/d[256][260] - As of December 31, 2024, the company's combined crude oil and natural gas proved reserves amounted to approximately 231.2 million boe, with 93% being natural gas[260] - Combined crude oil and natural gas proved reserves were 231 million boe, with 55% being proved developed reserves[310] - The total proved reserves increased from 199.0 million boe in 2023 to 231.2 million boe in 2024, reflecting successful extensions and discoveries[343] - The company has proved developed and undeveloped reserves totaling 231.2 million barrels of oil equivalent (boe), which includes 17.2 million barrels of liquid hydrocarbons and 1,284.2 billion cubic feet of natural gas[338] - Proved developed reserves of crude oil equivalent represented 55% of total proved reserves, equating to approximately nine years of production at 2024 volumes[339] - There was a 46% increase in proved undeveloped reserves in 2024 compared to 2023, primarily due to successful drilling activities[349] - The independent audit by GaffneyCline covered 98% of the company's estimated proved reserves as of December 31, 2024[337] - The reserves estimation process is supervised by a Reserves Technical Officer, ensuring compliance with SEC guidelines[350] Financial Performance - The oil and gas business segment recorded revenue of U.S.$730 million and an operating profit of U.S.$69 million for the fiscal year ended December 31, 2024[256] - Revenues from oil and gas operations in Argentina for 2024 totaled $730 million, an increase from $666 million in 2023[329] - The average production cost per barrel of oil equivalent in Argentina for 2024 was $17, a decrease from $18 in 2023[327] - The average sales price for oil in Argentina was $73 per barrel in 2024, up from $69 in 2023, while the gas price remained stable at $4 per thousand cubic feet[330] - The average gross margin for 2024 is projected to be 24, compared to 26 for 2023, indicating a slight decrease in profitability[395] - Average gross margin for 2024 is forecasted at $36/MWh, up from $35/MWh in 2023[397] Power Generation - The power generation segment achieved installed capacity of approximately 5,472 MW, representing about 13% of Argentina's total installed capacity, with revenue of U.S.$672 million and an operating profit of U.S.$204 million[257] - Installed capacity increased to 5,472 MW, with a market share of 13%[397] - The total net generation for 2024 is expected to be 3,633 GWh, reflecting a 15% increase compared to 2023[395] - Net generation for 2024 projected at 21,743 GWh, a 4% increase from 2023[397] - Sales for 2024 expected to reach 22,557 GWh, reflecting a 4% growth compared to 2023[397] Investments and Projects - The Vaca Muerta Oil Sur Project involves a 437 km pipeline with an estimated investment of U.S.$3 billion, aimed at enhancing crude oil evacuation and exports[266][269] - The company acquired a 20% stake in the FLNG Project, which is expected to start operations in September 2027, to monetize Vaca Muerta reserves and boost foreign currency inflows[271][272] - The "Proyecto Duplicar" increased the Allen - Puerto Rosales oil pipeline's capacity from 225,000 barrels per day to 540,000 barrels per day, with an investment of U.S.$1.4 billion[444] - VMOS project requires an estimated investment of U.S.$3 billion, aimed at constructing a 437 km pipeline for crude oil evacuation and exports[439] - The company invested U.S.$ 72.2 million in drilling and completion activities in 2024, converting approximately 12.7 million boe of proved undeveloped reserves to proved developed reserves[348] Production Activities - The company has a total of 688 productive wells in Argentina, with 272 being oil wells and 416 gas wells[312] - In 2024, the company drilled a total of 19 gross wells in Argentina, down from 44 in 2023, with 1 oil and 18 gas development wells[314] - Average daily production in 2024 was 4,772 barrels of crude oil and 440 million cubic feet of natural gas, with gas production increasing by 21% compared to 2023[318] - Total oil and gas production for 2024 was 1,742 thousand barrels of oil and 160,829 million cubic feet of gas, compared to 1,762 thousand barrels of oil and 132,652 million cubic feet of gas in 2023[321] - The company lifted hydrocarbons from 688 productive wells in Argentina as of December 31, 2024[317] Segment Performance - The petrochemicals segment generated revenue of U.S.$516 million and an operating profit of U.S.$43 million for the fiscal year ended December 31, 2024[259] - TGS's regulated segment revenues reached $427 million, a 249% increase from 2023[408] - TGS's midstream segment revenues totaled $215 million, a 97% increase compared to 2023[421] - Transener's annual revenues from extra high voltage power transmission amounted to U.S.$292 million, representing 89% of total revenues, a 103% increase compared to 2023[431] - Business development revenues were U.S.$38 million, accounting for 11% of total revenues, reflecting a 115% increase from 2023[432] Regulatory and Compliance - SE Resolutions No. 9/24 and No. 99/24 established increases of 73.9% and 25% in remuneration values for spot generation transactions[291] - The Independent Reserves Engineers Firm audited reserves estimates to conform to SEC guidelines, ensuring "reasonable certainty" about recoverability under current economic conditions[357] - The demand for electricity reached a new all-time high of 29,653 MW on February 1, 2024, exceeding the previous peak by 2%[430] - Transener recorded 0.35 failures per 100 km of line at the end of 2024, maintaining service quality consistent with international standards[430] - Transener's transparent remuneration policy has led to the continual renewal of most contracts, reflecting high customer satisfaction[435]
Marvell to Demonstrate Industry's First 400G/lane PAM4 Electrical-to-Optical Link Technology at OFC 2025
Prnewswire· 2025-03-31 13:00
Marvell® 400G Technology is an Industry Breakthrough Enabling a New Generation of PAM4 Network Connectivity SANTA CLARA, Calif., March 31, 2025 /PRNewswire/ -- Marvell Technology, Inc. (NASDAQ: MRVL), a leader in data infrastructure semiconductor solutions, will demonstrate the industry's first 400G/lane technology with complete electrical to optical link operating at 224 Gbaud at OFC 2025 taking place March 30-April 3, 2025 in San Francisco, CA. This technology was once considered impossible, but Marvell h ...
Pampa Energia(PAM) - 2024 Q4 - Annual Report
2025-03-11 14:34
2024 Annual Report To the shareholders of Pampa Energía S.A. ('Pampa,' the 'Company' or the 'Group'): Pursuant to the statutory rules and Bylaws currently in force, we submit for your consideration the Annual Report and Financial Statements for the 81 fiscal year that ended December 31, 2024. Pampa Energía ● 2024 Annual Report ● 3 Contents | 1. The fiscal year 2024 and the outlook | 5 | | --- | --- | | 2. Macroeconomic context | 7 | | 3. Corporate governance | 8 | | 4. The Argentine oil and gas market | 14 ...
Pampa Energia(PAM) - 2024 Q4 - Earnings Call Transcript
2025-03-06 19:51
Raquel Cardasz Good morning everyone and thank you for waiting. I'm Raquel Cardasz from IR and we would like to welcome everyone to Pampa Energia's Fourth Quarter 2024 Results Video Conference. We would like to inform you that this event is being recorded. All participants will be in listen-only mode during the presentation. After the company's remarks, there will be a Q&A session. Questions can only be submitted in writing through Zoom. Should any participants need help, please send us a chat message. Befo ...
Pampa Energia(PAM) - 2024 Q4 - Earnings Call Presentation
2025-03-06 15:02
The material that follows is a presentation of general background information about Pampa Energía S.A.("Pampa" or the "Company") as of the date of the presentation. It is information in summary form and does not purport to be complete. It is not intended to be relied upon as advice to potential investors. This presentation is strictly confidential and may not be disclosed to any other person. No representation or warranty, express or implied, is made concerning, and no reliance should be placed on, the accu ...
Pampa Energia: Attractive Valuation Despite Recent Gains
Seeking Alpha· 2025-02-13 12:03
Group 1 - Seeking Alpha welcomes Ivan Leyba as a new contributing analyst, encouraging others to share investment ideas for publication and potential earnings [1] - The new analyst has over 10 years of experience in accounting, auditing, and tax, with a focus on global macro strategy and value investing in sectors like energy, real estate, and utilities [2] - The analyst emphasizes the importance of studying companies with competitive advantages, good management, and strong future prospects, particularly those with solid cash flow and healthy margins [2] Group 2 - The article does not provide any specific company or industry analysis, focusing instead on the background and expertise of the new analyst [3][4]
Marvell Unveils Industry's First 3nm 1.6 Tbps PAM4 Interconnect Platform to Scale Accelerated Infrastructure
Prnewswire· 2024-12-03 14:00
Core Insights - Marvell Technology, Inc. has introduced the Ara platform, the first 3nm 1.6 Tbps PAM4 interconnects platform, which reduces optical module power by over 20% to support the increasing bandwidth demands of AI workloads [1][2][3] - The Ara platform integrates eight 200 Gbps electrical lanes and eight 200 Gbps optical lanes, enabling a compact design that simplifies module design complexity and reduces costs [2][4] - The anticipated unit shipments of PAM4 DSPs are expected to triple from 2024 to 2029, reaching nearly 127 million units annually, indicating a strong market demand for this technology [3] Company Overview - Marvell has a long-standing leadership in PAM4 optical DSP technology, with Ara being the latest advancement in a series of innovations [2][3] - The company emphasizes partnerships with leading technology firms to deliver data infrastructure solutions that meet current and future needs [6] Product Features - Ara supports 200 Gbps per channel, enhancing bandwidth for AI-driven applications and ensuring backward compatibility with previous generations [4] - The platform includes a high-swing laser driver and PAM4 modulation, which are critical for efficient high-speed data transmission in AI and cloud applications [4] - Enhanced crossbar switching capabilities and support for both InfiniBand and Ethernet provide flexibility across diverse network topologies [4] Availability - The Ara platform is set to sample to select customers in Q1 2025, indicating a forthcoming market introduction [5]