Core Viewpoint - The development of high-end medical device industry in Shanghai aims to enhance global competitiveness, with specific targets set for 2027, including over 500 new domestic third-class medical device registrations and over 100 products approved in overseas markets [1] Group 1: Industry Overview - The medical device CDMO (Contract Development and Manufacturing Organization) sector is compared to "precision handicrafts," indicating a more specialized and fragmented market compared to the "heavy industry" nature of biopharmaceutical CDMOs [3][5] - The market size of China's medical device industry is projected to reach 1.2 trillion yuan (approximately 1.2 trillion CNY) by 2024, highlighting significant growth potential [3] Group 2: CDMO Development and Challenges - Despite the growth potential, the medical device CDMO sector faces challenges, including a lack of large-scale providers akin to WuXi AppTec in biopharmaceuticals, and a predominance of low-value consumables in the current CDMO offerings [1][3] - The complexity and non-standard nature of medical devices make it difficult to establish a mature CDMO ecosystem, as the industry requires significant investment and expertise across multiple disciplines [6][7] Group 3: Market Dynamics and Trends - Many medical device companies prefer to build their own production lines to maintain control over core technologies and supply chains, with outsourcing primarily driven by cost efficiency and access to specialized capabilities [5][10] - The trend towards self-built production systems is evident as companies progress to mass production stages, although initial stages may benefit from CDMO partnerships [5][10] Group 4: Future Outlook - The future of medical device CDMOs in China is expected to improve as companies focus on specialization and collaboration with academic and research institutions, enhancing the overall ecosystem [7][12] - The integration of CDMO platforms into global supply chains is crucial for the competitiveness of Chinese medical device companies, with some platforms already establishing international R&D and manufacturing centers [12][13]

证券代码：603259 证券简称：药明康德 公告编号：临2025-065 2025年9月25日，由于市场环境变化，投资基金全体合伙人一致决议对投资基金财产进行清算。投资基 金尚无已完成交割的投资项目。截至本公告披露日，药明一期对投资基金实缴出资人民币24,000万元。 药明一期预计将收回投资本金24,000万元及相关利息收益。 本次投资终止不会对公司的财务及经营活动产生实质影响，不存在损害公司及全体股东利益的情形。 无锡药明康德新药开发股份有限公司 关于认购私募基金份额的进展公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重大遗漏，并对其内容 的真实性、准确性和完整性承担法律责任。 2023年10月20日，无锡药明康德新药开发股份有限公司（以下简称"公司"）全资子企业无锡药明康德一 期投资企业（有限合伙）（以下简称"药明一期"）与上海华平私募基金管理有限公司及其他合伙人签署 有限合伙协议，约定由药明一期认缴华平大健康产业投资（无锡宜兴）合伙企业（有限合伙）（以下简 称"投资基金"）不超过60,000万元人民币的投资基金份额（以下简称"本次投资"）。具体内容详见公司 于2023年10 ...

2025年9月25日，由于市场环境变化，投资基金全体合伙人一致决议对投资基金财产进行清算。投资基 金尚无已完成交割的投资项目。截至本公告披露日，药明一期对投资基金实缴出资人民币2.4亿元。药 明一期预计将收回投资本金2.4亿元及相关利息收益。 药明康德(02359)公布，2023年10月20日，公司全资子企业无锡药明康德一期投资企业(有限合伙)(以下 简称"药明一期")与上海华平私募基金管理有限公司及其他合伙人签署有限合伙协议，约定由药明一期 认缴华平大健康产业投资(无锡宜兴)合伙企业(有限合伙)(以下简称"投资基金")不超过6亿元人民币的投 资基金份额。 ...

2025 年 9 月 25 日，由于市场环境变化，投资基金全体合伙人一致决议对投资基金财产进行清算。投资 基金尚无已完成交割的投资项目。截至本公告披露日，药明一期对投资基金实缴出资人民币2.4亿元。 药明一期预计将收回投资本金2.4亿元及相关利息收益。 智通财经APP讯，药明康德(02359)公布，2023 年 10 月 20 日，公司全资子企业无锡药明康德一期投资 企业(有限合伙)(以下简称"药明一期")与上海华平私募基金管理有限公司及其他合伙人签署有限合伙协 议，约定由药明一期认缴华平大健康产业投资(无锡宜兴)合伙企业(有限合伙)(以下简称"投资基金")不超 过6亿元人民币的投资基金份额。 ...

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部分內容而產生或 因依賴該等內容而引致之任何損失承擔任何責任。 海外監管公告 本海外監管公告乃由本公司根據香港聯合交易所有限公司證券上市規則第 13.10B條作出。 WUXI APPTEC CO., LTD. * 無錫藥明康德新藥開發股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：2359） 无锡药明康德新药开发股份有限公司 关于认购私募基金份额的进展公告 茲載列本公司在上海證券交易所網站刊登的以下資料中文全文，僅供參閱。 承董事會命 無錫藥明康德新藥開發股份有限公司 董事長 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 李革博士 2023 年 10 月 20 日，无锡药明康德新药开发股份有限公司（以下简称"公 司"）全资子企业无锡药明康德一期投资企业（有限合伙）（以下简称"药明一 期"）与上海华平私募基金管理有限公司及其他合伙人签署有限合伙协议，约 定由药明 ...

无锡药明康德新药开发股份有限公司 证券代码：603259 证券简称：药明康德 公告编号：临 2025-065 关于认购私募基金份额的进展公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 2023 年 10 月 20 日，无锡药明康德新药开发股份有限公司（以下简称"公 司"）全资子企业无锡药明康德一期投资企业（有限合伙）（以下简称"药明一 期"）与上海华平私募基金管理有限公司及其他合伙人签署有限合伙协议，约 定由药明一期认缴华平大健康产业投资（无锡宜兴）合伙企业（有限合伙）（以 下简称"投资基金"）不超过 60,000 万元人民币的投资基金份额（以下简称"本 次投资"）。具体内容详见公司于 2023 年 10 月 21 日在上海证券交易所网站 （www.sse.com.cn）及相关指定媒体披露的《关于认购私募基金份额的公告》（公 告编号：临 2023-062）。 2025 年 9 月 25 日，由于市场环境变化，投资基金全体合伙人一致决议对投 资基金财产进行清算。投资基金尚无已完成交割的投资项目。截至本公告披露 日，药明一期 ...

Core Viewpoint - Daiwa maintains a "Buy" rating for WuXi AppTec (02359) and raises the target price from HKD 128 to HKD 134, reflecting a 3% increase in revenue and earnings per share forecasts for the company from 2023 to 2027 [1] Group 1: Financial Performance - The company produced 4 out of the 10 best-selling chemical drugs last year and is expected to receive FDA approval for 8 out of 40 small molecule drugs between 2024 and the first half of 2025 [1] - Management anticipates that WuXi TIDES business will see a year-on-year revenue growth of over 80% this year [1] Group 2: Product Development - The company is currently producing 23 GLP-1 drugs, an increase from 21 disclosed in January and 19 in September of last year, with 16 of these in Phase 2 and Phase 3 clinical trials, capturing 26% of the market share [1] Group 3: Future Operations - The first small molecule factory at the Singapore API base is expected to commence operations in 2027, followed by the first TIDES factory in the second quarter of 2028 and a second small molecule factory in the fourth quarter of 2029 [1] - The DP base in Delaware, USA, is expected to begin operations in the fourth quarter of next year, with sterile filling/completion capacity anticipated by the fourth quarter of 2027 [1]

Core Viewpoint - Daiwa maintains a "Buy" rating for WuXi AppTec (603259) with a target price raised from HKD 128 to HKD 134, reflecting an optimistic outlook on the company's revenue and earnings growth [1] Revenue and Earnings Forecast - The firm has increased its revenue and earnings per share forecasts for the company by 3% for the years 2023 to 2027, driven by higher revenue expectations from WuXi's chemical business [1] Product Development and Market Position - WuXi produced 4 out of the 10 best-selling chemical drugs last year and is expected to have 8 out of 40 small molecule drugs approved by the FDA between 2024 and the first half of 2025 [1] - The company is currently developing 23 GLP-1 drugs, an increase from 21 in January and 19 in September of the previous year, with 16 of these in Phase 2 and Phase 3 clinical trials, capturing 26% of the market share [1] Business Growth Expectations - Management anticipates that WuXi's TIDES business will see a year-on-year revenue growth of over 80% this year [1] Future Operational Plans - The first small molecule factory at the Singapore API site is expected to commence operations in 2027, followed by the first TIDES factory in the second quarter of 2028 and a second small molecule factory in the fourth quarter of 2029 [1] - The DP base in Delaware, USA, is projected to begin operations in the fourth quarter of next year, with sterile filling/completion capabilities expected by the fourth quarter of 2027 [1]

Core Viewpoint - Daiwa maintains a "Buy" rating for WuXi AppTec, raising the target price from HKD 128 to HKD 134, reflecting a 3% increase in revenue and earnings per share forecasts for the company from 2023 to 2027 due to higher revenue expectations in its chemical business [1] Group 1: Financial Performance - The company produced 4 out of the 10 best-selling chemical drugs last year and is expected to have 8 out of 40 small molecule drugs approved by the FDA between 2024 and the first half of 2025 [1] - Management anticipates that WuXi TIDES business will see over 80% year-on-year revenue growth this year [1] Group 2: Production Capacity and Future Plans - The first small molecule factory at the Singapore API site is expected to be operational by 2027, followed by the first TIDES factory in the second quarter of 2028, and a second small molecule factory by the fourth quarter of 2029 [1] - The DP site in Delaware, USA, is expected to be operational by the fourth quarter of next year, with sterile filling/completion capabilities anticipated by the fourth quarter of 2027 [1]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部分內容而產生或 因依賴該等內容而引致之任何損失承擔任何責任。 WUXI APPTEC CO., LTD. * 無錫藥明康德新藥開發股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：2359） 海外監管公告 承董事會命 無錫藥明康德新藥開發股份有限公司 董事長 李革博士 香港，2025年9月23日 截至本公告日期，本公司董事會包括執行董事李革博士、陳民章博士、楊青博士及張朝暉先生； 非執行董事童小幪先生及吳亦兵博士；以及獨立非執行董事盧韶華女士、俞衛博士、張新博士、 詹智玲女士及冷雪松先生。 * 僅供識別 FANGDA PARTNERS http://www.fangdalaw.com 本海外監管公告乃由本公司根據香港聯合交易所有限公司證券上市規則第 13.10B條作出。 茲載列本公司在上海證券交易所網站刊登的以下資料中文全文，僅供參閱。 2025 年第二次临时股东大会的法律意见书 致：无锡药明康德新药开发股份有限公司 上海市方达（北京）律师事务 ...