股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年12月31日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: WuXi Biologics (Cayman) Inc. 藥明生物技術有限公司*（於開曼群島註冊成立的有限公司）*僅供識別 呈交日期: 2026年1月6日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 02269 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 6,000,000,000 | USD | 0.000008333333 | USD | | 50,000 | | 增加 / 減少 (-) | | | 0 | | | USD | | 0 | | 本月底結存 | | | 6,000,000,000 | ...

Core Insights - WuXi Biologics has been recognized for its excellence in ESG disclosure by being included in the "Outstanding ESG Disclosure List" of the 2025 Hong Kong ESG Reporting Awards (HERA), marking a significant milestone in its commitment to transparency and responsible governance [1] - The company has received multiple accolades for its ESG efforts, including the "ESG Reporting Exemplary Award" in 2024, demonstrating its ongoing progress in sustainable development [1] - WuXi Biologics emphasizes the importance of transparent ESG disclosure as a competitive advantage in the current business environment, aiming to build trust with global clients, investors, and regulatory bodies [1] ESG Achievements - The CEO and Chairman of the ESG Committee, Dr. Chen Zhisheng, stated that transparency is the foundation of trust, and the company is committed to sharing its ESG journey to create long-term social and environmental value [2] - WuXi Biologics is a member of the UN Global Compact and the Pharmaceutical Supply Chain Initiative, actively promoting sustainable development strategies and receiving widespread industry recognition [2] - The company has achieved the highest AAA ESG rating from MSCI, a "Platinum" rating from EcoVadis, and inclusion in the Dow Jones Sustainability Index (DJSI), among other accolades, showcasing its outstanding performance in sustainability [2] Company Overview - WuXi Biologics (stock code: 2269.HK) is a leading global Contract Research, Development, and Manufacturing Organization (CRDMO) that provides comprehensive end-to-end services to help partners discover, develop, and manufacture biologics [3] - The company employs over 12,000 staff across China, the US, Ireland, Germany, and Singapore, offering efficient and cost-effective biologics solutions through its professional service teams and advanced technologies [3] - As of June 30, 2025, WuXi Biologics has supported clients in developing and producing a total of 864 projects, including 24 commercial production projects, highlighting its significant role in accelerating global biologics R&D [3]

Core Insights - WuXi Biologics has been recognized for its commitment to sustainability and transparency by receiving the Outstanding ESG Disclosure award at the Hong Kong ESG Reporting Awards (HERA) 2025, marking a significant achievement in its ESG journey [1][2] - The company emphasizes that transparent ESG reporting serves as a strategic advantage, enhancing trust and confidence among stakeholders, including clients, investors, and regulators [2][3] ESG Commitment - WuXi Biologics has a history of receiving accolades for its ESG efforts, including the ESG Report Benchmark Award from HERA in the previous year, which underscores the consistency of its progressive ESG initiatives [2] - The company actively participates in global sustainability initiatives, such as the United Nations Global Compact (UNGC) and the Pharmaceutical Supply Chain Initiative (PSCI), and has received numerous recognitions, including an MSCI AAA Rating and a Platinum Medal from EcoVadis [4] Business Operations - As of June 30, 2025, WuXi Biologics supports 864 integrated client projects, with 24 of these in commercial manufacturing, showcasing its extensive operational capabilities [6] - The company employs over 12,000 skilled professionals across multiple countries, including China, the United States, Ireland, Germany, and Singapore, leveraging its expertise to provide efficient and cost-effective biologics solutions [6] Sustainability Focus - WuXi Biologics views sustainability as essential for long-term business growth and is committed to driving green technology innovations to offer advanced Green CRDMO solutions [7] - The company aims to create shared value by collaborating with stakeholders to foster positive social and environmental impacts, promoting responsible practices throughout the value chain [7]

Group 1 - The core viewpoint of the article highlights a general increase in the pharmaceutical outsourcing sector, with notable stock price rises for companies such as WuXi Biologics (6.11%), Kelun Pharmaceutical (5.52%), and others [1] - According to a report from Century Securities, the recent NDAA legislation has led to a reduction in geopolitical risks, positively impacting the industry [1] - In the first three quarters, the total amount of license-out agreements for innovative drugs in China reached a historical high, indicating a continuous improvement in the innovation drug sector [1] Group 2 - The CXO sector is experiencing a recovery in performance and new orders, with market attention shifting towards preclinical safety evaluation assets [1] - The CXO industry, as an upstream segment of the innovative drug supply chain, is expected to benefit from the enhanced competitiveness of domestic innovative drugs, leading to a rebound in industry prosperity [1] - The outlook for CXO is positive, with expectations for both performance and valuation recovery following a complete industry cycle [1]

Group 1 - The pharmaceutical outsourcing sector is experiencing a general increase, with notable stock price rises for companies such as WuXi Biologics (6.11%), Kelun Pharmaceutical (5.52%), and others [1] - A recent report from Century Securities indicates that the NDAA bill has been implemented, leading to a reduction in geopolitical risks [1] - In the first three quarters, the total amount of license-out agreements for innovative drugs in China reached a historical high, indicating a continuous improvement in the innovative drug industry [1] Group 2 - The performance and new orders for CXO companies are showing signs of improvement, with the market beginning to focus on preclinical safety evaluation assets [1] - CXO companies, as part of the upstream of the innovative drug industry chain, are expected to benefit from the enhanced competitiveness of domestic innovative drugs, leading to a recovery in industry prosperity [1] - The industry is anticipated to see a dual recovery in both performance and valuation for CXO companies [1]

Group 1 - The core viewpoint of the article highlights a rebound in two major sectors of Hong Kong stocks: internet and innovative pharmaceuticals, with the Hong Kong Stock Connect Technology ETF (159101.SZ) rising by 1.5% [1] - Key stocks such as WuXi Biologics increased by over 6%, and WuXi AppTec rose by over 4%, while Tencent, Meituan, and Alibaba experienced slight increases [1] - After three months of adjustment, the crowdedness in these two core sectors has returned to low levels, with recent catalysts for growth including Tencent's release of the mixed reality model and Baidu's Kunlun chip accelerating towards an IPO, projected to exceed 2 billion yuan in revenue by 2025 [1] Group 2 - The passing of the U.S. National Defense Authorization Act for fiscal year 2026 on December 18 is seen as beneficial for CXO companies like WuXi Biologics and WuXi AppTec, as the new version of the biosafety law does not specifically name any companies [1] - Improved relations between the two countries have also boosted market risk appetite [1] - The Hong Kong Stock Connect Technology ETF (159101.SZ) tracks the National Index for Hong Kong Stock Connect Technology, which has reduced exposure to consumer retail while increasing allocation to biopharmaceuticals and hardware equipment, allowing for greater index elasticity [1]

Group 1 - Hong Kong pharmaceutical stocks showed a significant rebound this morning, particularly in the CRO and innovative drug sectors [1] - Kelaiying (06821.HK) increased by 6.28%, reaching HKD 77 [1] - WuXi Biologics (02269.HK) rose by 6.11%, trading at HKD 34.72 [1] - Sangfor Pharmaceuticals (01530.HK) gained 5.04%, priced at HKD 26.68 [1] - Innovent Biologics (09969.HK) saw an increase of 4.25%, with shares at HKD 13.74 [1]

Core Viewpoint - The Hong Kong technology sector experienced a rebound on December 19, with significant gains in biotechnology stocks, particularly benefiting from the recent passage of the 2026 National Defense Authorization Act (2026 NDAA) in the U.S. [1] Group 1: Market Performance - The Hang Seng Biotechnology and Hong Kong Stock Connect Technology Indexes led the gains, with WuXi Biologics rising over 5% and WuXi AppTec increasing more than 4% [1] - Other notable performers included Innovent Biologics and CanSino Biologics, both of which saw increases exceeding 2% [1] Group 2: Regulatory Impact - The new version of the U.S. bioterrorism law did not specifically name any companies, which is seen as a significant positive for Chinese CXO companies, including WuXi AppTec and WuXi Biologics, that have been under pressure from previous regulations [1] Group 3: Investment Opportunities - There are low-positioning opportunities in related ETFs covering Hong Kong CXO leaders, specifically the Hang Seng Pharmaceutical ETF (159892.SZ) and the Hong Kong Stock Connect Technology ETF (159101.SZ) [1]

Core Viewpoint - WuXi Biologics has signed a strategic cooperation memorandum with the Qatar Free Zones Authority to enhance collaboration in biopharmaceutical manufacturing, research, and innovation [1] Group 1 - The signing ceremony was attended by Qatar's Minister of Commerce and Industry, Faisal [1]

股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年11月30日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: WuXi Biologics (Cayman) Inc. 藥明生物技術有限公司*（於開曼群島註冊成立的有限公司）*僅供識別 呈交日期: 2025年12月4日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 02269 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 6,000,000,000 | USD | 0.000008333333 | USD | | 50,000 | | 增加 / 減少 (-) | | | 0 | | | USD | | 0 | | 本月底結存 | | | 6,000,000,000 | ...