Core Insights - Crinetics Pharmaceuticals has initiated the CALM-CAH Phase 3 trial for atumelnant, a novel oral ACTH receptor antagonist aimed at treating classic congenital adrenal hyperplasia (CAH) [1][2] - The trial will assess atumelnant's effectiveness in normalizing adrenal androgen levels and reducing glucocorticoid levels to physiological ranges, setting a new standard for disease control assessment [2][3] - Atumelnant is the first small molecule ACTH receptor antagonist in late-stage clinical development, showing promising results in a Phase 2 study with significant reductions in key biomarkers [2][4] Company Overview - Crinetics Pharmaceuticals focuses on transforming the treatment of endocrine diseases and related tumors, emphasizing patient needs and innovative therapies [5] - The company has a robust pipeline, including its lead product PALSONIFY™ for acromegaly and atumelnant for CAH and ACTH-dependent Cushing's syndrome [6][7] - Crinetics has received Orphan Drug Designation from the FDA for atumelnant, highlighting its potential impact on rare diseases [3]

FOSTER CITY, Calif., Dec. 11, 2025 (GLOBE NEWSWIRE) -- Terns Pharmaceuticals, Inc. (“Terns” or the “Company”) (Nasdaq: TERN), a clinical-stage oncology company, today announced the closing of its previously announced underwritten public offering of 18,687,500 shares of its common stock, including 2,437,500 shares sold pursuant to the underwriters’ exercise in full of their option to purchase additional shares, at a public offering price of $40.00 per share, before underwriting discounts and commissions. The ...

MITCHEL FIELD, N.Y., Dec. 11, 2025 (GLOBE NEWSWIRE) -- Frequency Electronics, Inc. (“FEI” or the “Company”) (NASDAQ-FEIM) is pleased to announce its financial results for the second quarter and fiscal year 2026. Revenue for the three and six months ended October 31, 2025, was approximately $17.1 million and $30.9 million, respectively, compared to $15.8 million and $30.9 million, respectively, reported for the same period of fiscal year 2025. Operating income for the three and six months ended October 31, 2 ...

TORONTO, Dec. 11, 2025 (GLOBE NEWSWIRE) -- Cartier Silver Corporation (CSE:CFE) (“Cartier Silver” or the “Company”) announces the grant of stock options to directors, officers and consultants to purchase an aggregate of 3,430,000 common shares of the Company, exercisable at $0.24 per share at any time on or before December 11, 2030. The grants are subject to the terms of Cartier Silver’s stock option plan. In accordance with regulatory requirements, any shares issued pursuant to the exercise of such options ...

Core Points - Tevogen Bio Holdings Inc. announced a significant donation of 230,000 shares from its Founder and CEO, Dr. Ryan Saadi, to the Warren Township Honorary Policemen's Benevolent Association [2][10] - The donation aims to support local community initiatives, including safety equipment for police officers and community welfare programs [3][6] Company Overview - Tevogen is a next-generation healthcare enterprise focused on affordability, efficiency, and scientific rigor, utilizing advanced technologies for developing life-saving therapies [11] - The company has a diverse pipeline that includes programs in virology, oncology, and neurology, leveraging its proprietary ExacTcell™ platform [12] Community Engagement - The donation reflects Tevogen's commitment to community responsibility and enhancing the safety of local law enforcement [9][8] - The funds will be allocated for critical equipment to improve the safety and effectiveness of police services in Warren Township [6][7]

ATLANTA, Dec. 11, 2025 (GLOBE NEWSWIRE) -- Gray Media, Inc. is marking the 250th anniversary of the United States of America with a company-wide storytelling project that showcases how local people, places, and moments have shaped the American story. Through its “We the People” initiative, Gray stations across the country are producing hundreds of original stories that connect national history to hometown experiences. “America 250 is not just about a date on the calendar; it’s about who we are as a country ...

GUADALAJARA, Mexico, Dec. 11, 2025 (GLOBE NEWSWIRE) -- Grupo Aeroportuario del Pacífico, S.A.B. de C.V. (NYSE: PAC; BMV: GAP) (“GAP”) announces that, during its Ordinary and Extraordinary General Shareholders’ Meeting, with a quorum of 88.1% of its shareholders, around 96% of the votes cast approved the business combination of the Cross Border Xpress (CBX) and the provision of technical assistance and technology transfer services. This business combination will be carried out through the merger of various e ...

New Live-Action Banner to Produce Family and Youth Entertainment; First Project, “Real Santa” BEVERLY HILLS, Calif., Dec. 11, 2025 (GLOBE NEWSWIRE) -- Kartoon Studios (NYSE American: TOON), a global producer and distributor of children’s and family entertainment, and AETH Entertainment, a full service entertainment studio, today jointly announced they have teamed up to launch TaleSphere Studios, a joint venture that will produce live-action youth and family focused entertainment. “This marks an exciting ven ...

Core Insights - AlphaTON Capital Corp has entered a five-year Enterprise Colocation Service Agreement with atNorth AB to establish decentralized AI infrastructure supporting the Telegram ecosystem [1][3] - The agreement includes an initial GPU deployment capacity of 2.2 MW, expandable to 4.3 MW, positioning AlphaTON to leverage the growing AI infrastructure-as-a-service market, projected to reach $247 billion by 2030 [3][4] Agreement Highlights - The 60-month agreement starts on February 1, 2026, and secures GPU deployment capacity expansion [3] - The initial capacity of 2.2 MW can be expanded to 4.3 MW, allowing for the deployment of thousands of enterprise-grade GPUs [3][5] - The infrastructure will support 2,000+ high-performance GPUs initially, with potential expansion to over 4,000 GPUs [6] Infrastructure Details - The facility is located at atNorth's Tier 3 certified SWE01 facility in Kista, Sweden, with a peak power capacity of 2,230 kW and a Right of First Refusal for an additional 2,100 kW [5][6] - The infrastructure features sustainable Nordic power with competitive Power Usage Effectiveness (PUE) ratings between 1.4-1.7 [5] - It includes robust N+1 redundancy to support mission-critical computing operations [5][6] Revenue Generation - The infrastructure will enable AlphaTON to generate revenue through AI-as-a-Service offerings for enterprise and developer customers, GPU compute marketplaces, and application-specific inference services [12] - The company aims to support Telegram's ecosystem of mini-apps and bots with high-performance computing services [12] Company Overview - AlphaTON Capital Corp is a leading technology public company scaling the Telegram super app, targeting an addressable market of 1 billion monthly active users [9] - The company employs a comprehensive M&A and treasury strategy, focusing on direct token acquisition and strategic ecosystem investments [9] - AlphaTON is also involved in drug development, targeting therapies for checkpoint resistance pathways [10]

For patients whose time to progression on immediate prior therapy was >18 months, median progression-free survival (“PFS”) was 12.4 months with gedatolisib + palbociclib + fulvestrant (“gedatolisib triplet”) and 10.0 months with gedatolisib + fulvestrant (“gedatolisib doublet”) versus 1.9 months for fulvestrantFor patients enrolled in the U.S., Canada, Western Europe, and Asia Pacific, median PFS was 16.6 months with the gedatolisib triplet and 7.1 months with the gedatolisib doublet versus 1.9 months for f ...