Core Insights - iRhythm Technologies presented new data at the 18th Asia Pacific Heart Rhythm Society and Japanese Heart Rhythm Society Joint Scientific Session, highlighting the performance of its Zio long-term continuous ECG monitoring system in diverse patient populations [1][7]. Group 1: Study Overview - The study, led by Dr. Hiro Kawata, analyzed 408,470 U.S. patients monitored between 2018 and 2022, comparing device compliance, performance, and arrhythmia detection between Asian and non-Asian populations [2][5]. - The analysis aimed to determine if racial and cultural differences impact the effectiveness of ambulatory cardiac monitoring [3]. Group 2: Key Findings - The findings indicated no significant differences in wear time, analyzable time, or arrhythmia detection yield between Asian and non-Asian patients, supporting the reliability of the Zio system across diverse populations [5][6]. - Median wear time was 13.6 days for Asian patients compared to 13.0 days for non-Asian patients, while analyzable ECG duration was 12.9 days for Asians versus 12.2 days for non-Asians [8]. - The arrhythmia detection rates were comparable, with Asian patients showing a 14.0% detection rate for atrial fibrillation compared to 14.3% for non-Asians [8]. Group 3: Implications for Japan - As Japan's population ages, the demand for advanced cardiac monitoring is increasing, with approximately 1.6 million tests prescribed annually [9]. - iRhythm's Zio ECG system, which allows for up to 14 days of continuous monitoring, represents a significant advancement over traditional monitoring options in Japan [10]. - The company is collaborating with local investigators to expand evidence and support the adoption of the Zio system in Japanese clinical practice [11]. Group 4: Supporting Evidence - The analysis adds to the growing body of evidence supporting the Zio LTCM service, which has been validated in previous studies such as CAMELOT and AVALON [12]. - iRhythm has generated over 2 billion hours of curated heartbeat data and more than 12 million patient reports, reinforcing its commitment to improving cardiac arrhythmia detection and management [13].

Core AI Holdings Overview - Core AI Holdings, Inc. has announced the formation of Core Digital, a wholly-owned subsidiary aimed at entering the digital marketing sector [1][2] - The company is focused on leveraging its AI capabilities to expand into one of the fastest-growing technology markets globally [2] Strategic Goals - Core Digital will integrate Core AI's proprietary machine learning and media analytics platform to create an AI-driven digital marketing ecosystem [2] - The initiative is part of a broader strategy to expand into high-growth digital media segments and establish a strong operational presence in Asia [7] - Core Digital is expected to be operational by the first quarter of 2026 [3] Company Background - Core AI Holdings is an international AI-driven mobile games developer and publisher, having developed over 2,200 games and achieved over 800 million downloads [4] - The company aims to harness AI to build transformative offerings across multiple verticals, with a global user base exceeding 40 million from over 140 countries [4]

Core Insights - Vera Bradley, Inc. has appointed Ivan Brockman to its Board of Directors effective November 17, 2025, bringing extensive experience in strategic decision-making and investment banking [1][2]. Company Overview - Vera Bradley, based in Fort Wayne, Indiana, is a leading designer of women's handbags, luggage, travel items, fashion and home accessories, and unique gifts, known for its innovative designs and iconic patterns [5]. Leadership and Experience - Ivan Brockman has three decades of experience advising senior management teams and investors, currently serving as a Senior Advisor to PJT Partners and previously holding significant roles at Citigroup and Goldman Sachs [2][3]. - Throughout his career, Mr. Brockman has advised on over $100 billion of strategic transactions with major companies including Google, Microsoft, and Amazon [2]. Investment Activities - Mr. Brockman is also an active private investor in various sectors, including technology and consumer startups, with notable early-stage investments in companies like LifeLock and FIGS [3]. Strategic Transformation - Mr. Brockman expressed enthusiasm about joining Vera Bradley during a critical period of the company's strategic transformation [4]. Business Segments - Vera Bradley operates through two reportable segments: VB Direct, which includes sales through its own stores and websites, and VB Indirect, which consists of sales to specialty retail locations and other channels [6].

RICHMOND, Calif., Nov. 21, 2025 (GLOBE NEWSWIRE) -- Sangamo Therapeutics, Inc. (Nasdaq: SGMO), a genomic medicine company, today announced that the U.S. Food and Drug Administration (FDA) has accepted Sangamo’s request for a rolling submission and review of the Biologics License Application (BLA) for isaralgagene civaparvovec, or ST-920, a wholly owned investigational gene therapy for the treatment of adults with Fabry disease. This acceptance follows Sangamo’s meeting with the FDA in October 2025 to discus ...

BELGRADE, Mont., Nov. 21, 2025 (GLOBE NEWSWIRE) -- Bridger Aerospace Group Holdings, Inc. (“Bridger”, “the Company” or “Bridger Aerospace”), (NASDAQ: BAER, BAERW), one of the nation’s largest aerial firefighting companies, today announced the planned retirement of Eric Gerratt, Chief Financial Officer. The Company also announced a succession plan for the CFO role, with the appointment of Director Anne Hayes as Deputy Chief Financial Officer and the appointment of Ernie Freedman as an independent director an ...

90-day trial will measure change in general fatigue in patients with chronic babesiosis following tafenoquine treatmentStudy will run approximately 12 months and enroll up to 100 patientsInternal estimates of the unmet medical need are between 4,400 and 190,000 cases annually, with no existing FDA-approved treatment for babesiosis WASHINGTON, Nov. 21, 2025 (GLOBE NEWSWIRE) -- 60 Degrees Pharmaceuticals, Inc. (NASDAQ: SXTP; SXTPW) (“60 Degrees Pharma” or the “Company”), a pharmaceutical company focused on de ...

SINGAPORE and NORTH BRUNSWICK, N.J. and HANGZHOU, China, Nov. 21, 2025 (GLOBE NEWSWIRE) -- Adlai Nortye Ltd. (NASDAQ: ANL) (the “Company” or “Adlai Nortye”), a clinical-stage biotechnology company focused on the development of innovative cancer therapies, today announced that members of its management team are scheduled to participate in the following investor conferences: The 8th Annual Evercore Healthcare ConferenceFormat: Fireside ChatHost: Jonathan MillerDate and Time: Tuesday, December 2, 2025; 4:15 pm ...

Company Also Names Industry Veteran Elizabeth Simer as COOATLANTA, Nov. 21, 2025 (GLOBE NEWSWIRE) -- Bitcoin Depot (“Bitcoin Depot” or the “Company”) (NASDAQ: BTM), a U.S.-based Bitcoin ATM (“BTM”) operator and leading fintech company, today announced a planned leadership transition designed to support the Company’s long-term strategy, operational scaling, and M&A objectives. Bitcoin Depot’s Board of Directors has appointed Scott Buchanan, the Company’s current President and Chief Operating Officer, as Chie ...

– Company to Receive $90 Million Total Payment – – Third Largest Global Market for Cardiovascular Prevention Represents Significant Global Growth Opportunity for NEXLETOL – ANN ARBOR, Mich., Nov. 21, 2025 (GLOBE NEWSWIRE) -- Esperion (NASDAQ: ESPR) today announced that Otsuka Pharmaceutical Co., Ltd. (Otsuka), the Company’s partner in Japan for the development and commercialization of NEXLETOL® (bempedoic acid) tablets, received National Health Insurance Price Listing and launched NEXLETOL for the treatment ...

LONDON, Nov. 21, 2025 (GLOBE NEWSWIRE) -- Diginex Limited (“Diginex” or the “Company”) (NASDAQ: DGNX), a recognized provider of Sustainability RegTech solutions, today announced that it has executed a non-binding memorandum of understanding (the “MOU”) to acquire The Remedy Project Limited (“Remedy”), a pioneering organization specializing in data-driven human rights risk assessment and worker-centered remediation protocols for global supply chains. The proposed acquisition combines Diginex’s AI-powered pla ...