Ad Hoc Announcement Pursuant to Art. 53 LR  Geneva, Switzerland, June 6, 2025 - Addex Therapeutics (SIX: ADXN and Nasdaq: ADXN), a clinical-stage biopharmaceutical company focused on developing a portfolio of novel small molecule allosteric modulators for neurological disorders, announced today robust anti-tussive activity of its novel gamma-aminobutyric acid sub-type B receptor (GABAB) positive allosteric modulator (PAM) in multiple preclinical models of chronic cough compared to reference drugs. Some of ...

Ad Hoc Announcement Pursuant to Art. 53 LR Geneva, Switzerland, June 6, 2025 - Addex Therapeutics (SIX: ADXN and Nasdaq: ADXN), a clinical-stage biopharmaceutical company focused on developing a portfolio of novel small molecule allosteric modulators for neurological disorders, announced today robust anti-tussive activity of its novel gamma-aminobutyric acid sub-type B receptor (GABAB) positive allosteric modulator (PAM) in multiple preclinical models of chronic cough compared to reference drugs. Some of ...

Group 1 - The focus has shifted towards offshore drilling, supply industry, and shipping, including tankers, containers, and dry bulk [1] - The fuel cell industry is being monitored as it is still in its early stages of development [1] Group 2 - The individual has extensive experience in auditing and trading, having navigated significant market events such as the dotcom bubble and the subprime crisis [2] - The research provided aims to maintain high quality despite language barriers [2]

Core Viewpoint - Defiance ETFs has launched the Defiance Daily Target 2X Short PLTR ETF (Ticker: PLTZ), which is the first 2X short single-stock ETF aimed at providing amplified daily inverse exposure to Palantir Technologies Inc. [1][2] Group 1: Fund Objectives and Structure - PLTZ aims to achieve daily investment results that correspond to -2 times (-200%) the daily percentage change of Palantir's stock price, making it a tactical tool for active traders to express bearish views on Palantir's short-term movements [2][3] - The fund is designed for knowledgeable investors who actively monitor their portfolios, as it pursues a daily inverse leveraged investment objective [3][4] Group 2: Company Background - Palantir Technologies Inc. was founded in 2003 to support U.S. intelligence operations and now provides software solutions for complex data environments across both public and private sectors [1] - The company develops software platforms that integrate data and enhance decision-making for commercial enterprises and government agencies, including defense and intelligence sectors [12] Group 3: Investment Strategy and Risks - The fund utilizes swap contracts and options based on the share price of Palantir, exposing it to risks similar to owning shares of Palantir [8] - The use of derivatives, including swaps and options, introduces additional risks such as market volatility, counterparty risk, and potential lack of liquidity [14][16][17]

Core Viewpoint - Silynxcom Ltd. has received a $140,000 purchase order from a special forces unit in the Asia-Pacific region, highlighting the company's expanding global presence and the increasing demand for its advanced communication solutions among elite military units [1][2]. Group 1: Company Overview - Silynxcom Ltd. specializes in the development and manufacturing of ruggedized tactical communication headset devices, which are field-tested and combat-proven [5]. - The company's in-ear headset systems are recognized for their durability, advanced technology, and critical in-ear sound protection, making them a preferred choice for defense organizations [2][5]. - Silynxcom's products are designed to meet the rigorous demands of elite military operations, enhancing operational effectiveness and safety through features like "talking from the ear" and environmental hearing [3][5]. Group 2: Recent Developments - The recent order from a prestigious special forces unit is seen as a testament to the reliability and effectiveness of Silynxcom's communication systems [3]. - The company has secured recent orders from elite units in various regions, including the Israel Defense Forces and European special forces units, further strengthening its position in the specialized tactical communications market [4]. Group 3: Product Features - Silynxcom's in-ear communication systems incorporate proprietary technology that allows for clear communication while protecting users' hearing in high-noise environments [3]. - The in-ear headsets provide 360° situational awareness by eliminating unsafe sounds while maintaining ambient environmental awareness [5].

Company Overview - Outset Medical, Inc. is a medical technology company focused on pioneering technology to reduce the cost and complexity of dialysis [3] - The Tablo® Hemodialysis System is FDA cleared for use from the hospital to the home, representing a significant technological advancement in dialysis [3] - Tablo serves as a single enterprise solution that can be utilized across the continuum of care, allowing dialysis to be delivered anytime, anywhere, and by anyone [3] Product Features - The integration of water purification and on-demand dialysate production enables Tablo to function as a "dialysis clinic on wheels" [3] - Tablo features 2-way wireless data transmission and a proprietary data analytics platform, promoting a holistic approach to dialysis care [3] Upcoming Events - Management will present at the Goldman Sachs 46th Annual Healthcare Conference on June 11, 2025, at 11:20 a.m. Eastern time [1] - A live and archived webcast of the presentation will be available on the "Investors" section of the Outset website [2]

Core Insights - GoPro, Inc. has appointed Mike Dennison to its Board of Directors, effective June 3, 2025 [1] - Dennison brings extensive experience in global manufacturing, product innovation, and brand leadership to GoPro [2] - He currently serves as CEO of Fox Factory Holding Corp., managing operations worth approximately $1.4 billion across 29 locations globally [2] Company Overview - GoPro is recognized for its ability to connect people to their passions through storytelling and innovation [3] - The company has been acknowledged as an employer of choice by Outside Magazine and U.S. News & World Report [4] - GoPro encourages customer engagement through initiatives like GoPro Awards, allowing users to submit photos and videos for potential features on social media [5]

Core Perspective - TJ Maxx launches "You Sponsored by TJ Maxx," a program aimed at providing sponsorship opportunities to everyday women, addressing the disparity in sponsorship support [1][4][8] Group 1: Program Overview - The program will award 10 women custom sponsorship deals to enhance their visibility, connections, and opportunities [2][6] - Each recipient will be paired with one of five influential Co-Sponsors from various fields, including athletics, arts, fashion, and entrepreneurship [2][5] Group 2: Key Findings from Survey - A TJ Maxx survey indicates that fewer than 10% of women currently have a sponsor, while 75% believe sponsorship would help them embrace their authentic selves [1][10] - The survey was conducted with 2,000 U.S. women aged 18-65, highlighting the need for increased support for women in various professional fields [10] Group 3: Sponsorship Benefits - Recipients will receive $20,000 in funding to support their personal or professional endeavors [6] - The program includes one-on-one mentorship with Co-Sponsors and introductions to their networks to facilitate further opportunities [6] - Visibility will be enhanced through storytelling on TJ Maxx's social media platforms, reaching millions of followers [6] Group 4: Historical Context - The initiative builds on the Maxx You Project, which has supported over 200,000 women since its inception in 2017, providing resources for women to pursue their authentic lives [11]

Core Viewpoint - Zefiro Methane Corp. has appointed Catherine Flax as Interim Chief Executive Officer, bringing extensive experience in investment banking and a commitment to leading the company in the evolving energy sector [2][5][6]. Company Overview - Zefiro Methane Corp. specializes in methane abatement and aims to be a significant player in the Active Sustainability movement, focusing on cleaning up air, land, and water sources affected by methane leaks [9]. - The company is recognized as North America's largest single plugger of wells and an originator of high-quality carbon offsets [1]. Leadership Background - Catherine Flax has a notable background, having served as Head of Commodity Derivatives (Americas) at BNP Paribas and CEO of Commodities EMEA at J.P. Morgan. She was named the Most Influential Woman in European Investment Banking in 2012 [3]. - Flax is also involved with the Securities Industry and Financial Markets Association (SIFMA) and serves on the board of the Independent System Operator for the New England Transmission grid [3]. Recent Activities - In 2025, Flax has been active in promoting Zefiro's initiatives, including speaking engagements and media appearances related to investment in alternative energy sources [4]. - The appointment of Flax follows the departure of Talal Debs, the previous CEO, who was recognized for his contributions as the company's founder [5]. Strategic Vision - Flax expressed a commitment to leading Zefiro through a period of growth and opportunity in the U.S. energy and resource sectors, emphasizing the company's readiness to adapt to technological and regulatory changes [6]. - The company aims to build the largest oilfield decommissioning business in North America while producing high-quality carbon offsets in the voluntary market [8].

Core Insights - BrightSpring Health Services, Inc. (BTSG) has made significant investments in process improvements and technology enhancements, leading to better care delivery efficiency and patient outcomes [1][4] - The company has achieved high ratings across various segments, with over 80% of Home Health branches rated 4 stars or better and patient satisfaction nearing 90% [1][8] Home Health Segment - Over 80% of Home Health branches achieved a 4-star rating or better, with declining 60-day hospitalization rates [1][8] - Patient satisfaction in the Home Health segment is approaching 90% [1] Hospice Operations - Hospice operations have outperformed, with visit frequency and time spent with patients exceeding the national average by 50% [2] - Quality index scores in the Hospice segment have reached record highs [2] Rehabilitation and Personal Care Segments - Patient satisfaction in the Rehab segment remains strong at 98% [2] - The Personal Care segment achieved its highest-ever rating with a satisfaction score of 4.6 out of 5 [2] Community Living and Infusion Segments - Community Living recorded its lowest number of audit findings to date, which is 40% better than the industry average [2] - The Infusion segment reported a 96% therapy completion discharge rate and a 95% patient satisfaction score [3] Operational Metrics - Home and Community Pharmacy Services achieved near-perfect operational metrics, including 99.999% dispense accuracy and 99% order completeness [3] Competitive Landscape - Amedisys (AMED) maintains a focus on clinical distinction, achieving an average Quality of Patient Care star rating of 4.18 across all providers, with 88% of care centers rated 4 stars or higher [5] - Addus HomeCare Corporation (ADUS) has launched the Care Advantage Program to enhance preventive care and patient satisfaction through a tech-enabled approach [6] Stock Performance and Valuation - Shares of BrightSpring have gained 104.1% in the past year, significantly outperforming the industry, which saw a decline of 21.7% [7] - BTSG trades at a forward price-to-earnings ratio of 21.59, above the industry's 14.25 [9] Earnings Estimates - The Zacks Consensus Estimate for BTSG's earnings has been on the rise over the past 30 days, with current quarter estimates at $0.22 and next year at $1.19 [10][11]