[music] [applause] Your thoughts shape your leadership. Leadership shapes communities and communities shape the future. Your mindset is your greatest leadership asset and it needs to be recognized as such.Recent brain imaging from Queens University found that we have over 6,000 distinct thoughts a day. And that's just during our waking hours. They tracked changes in brain activity to measure when our minds shift from one thought to the next.That's hundreds of mental shifts every hour, whether we notice them ...

Just by the show of hands, do you believe that no one is really disadvantaged. No one is disadvantaged. Some people are disadvantaged.H interesting. But you see, if no one is truly disadvantaged like the topic says, how do we explain poverty. And what about people that were born with impaired hearing.And this is speaking to those that said that no one is really disadvantaged. People with impaired sight, malformed limbs. How can someone thrive when life actually seems unfair.Is that not a disadvantage and in ...

At different times in our lives, we're all bound to reach a stage that feels like the edge of our given capacity. When everything we once knew stops working the way it used to, and we're forced to confront who we've become at that limit. And we do have an instinct to adapt.It's not just part of what makes us human. It's also how we survive change in our environment. It's how we evolve through it and most importantly despite it.But what happens when the environment itself changes. And what does adaptation lo ...

What if healing emotion control is not about finding the right words but rather about finding the right reason. Imagine waking up every day feeling like you are drowning in emotions that you cannot escape from. Well, for me, this was my reality for many years until I was able to discover a way to take struggle and pain and turn it into something beautiful.Now, being a performing artist, drama teacher, creative, I've often been wondering and exploring ways to understand how creativity impacts our minds. So t ...

[music] Good morning everyone. When I first heard I had to speak on the theme beneath the silicon, I was utterly stumped. I had literally no idea what the theme meant.And so I decided to turn to Google. I searched up periodic table of elements. And it turns out that three rows beneath silicon in the periodic table is lead. So I concluded that I needed to talk about the lead that is beneath the silicon.The next step in my quest was to brush up on the history of lead. It turns out that during medieval times, ...

Core Insights - NRx Pharmaceuticals has amended its Investigational New Drug filing for NRX-101 to include its use in conjunction with Transcranial Magnetic Stimulation (TMS) for treating depression, including suicidal depression [1][8] Group 1: Clinical Findings - NRX-101 has shown a promising new indication that may expedite its commercialization as a Breakthrough Therapy-designated drug, with evidence indicating a more than two-fold benefit in symptom reduction when combined with TMS [2] - Clinical trials reported a 75% clinical response and a 40% remission rate in patients treated with D-cycloserine (DCS) alongside TMS [2] - A recent study using a modern TMS device and a one-day protocol combined with DCS showed an 87% clinical response and a 72% remission rate at six weeks [3] Group 2: Mechanism and Efficacy - Nonclinical evidence suggests that D-cycloserine enhances neuroplasticity when used with TMS, potentially leading to a response rate exceeding 80%, which is significantly higher than the 30% success rate associated with traditional SSRI antidepressants [4] - NRX-101 combines D-cycloserine with a low dose of lurasidone, which is already approved for depression treatment and has anti-hallucinatory properties, addressing the contraindication of DCS in depression patients [5] Group 3: Future Prospects - The company plans to conduct well-controlled trials with approximately 120 participants to further validate the clinical benefits observed in earlier studies [6] - NRx anticipates that over 1 million Americans may be treated with TMS annually by 2030, creating a substantial market opportunity for NRX-101 [7] - The company has published an Expanded Access policy for NRX-101, allowing physicians to request information for patients who may benefit from the treatment [7]

I'm going up. >> At first glance, it appears Kathy Denapoli is controlling her own hand. >> Squeeze, squeeze, squeeze, squeeze, squeeze.>> But the 63-year-old grandmother, recovering from a severe spinal injury, isn't operating solo because across the table. >> And Kathy, I'm going to put my hand around the bottle. >> Keith Thomas, a quadripollegic just like Kathy, aids every movement.>> She lift the bottle up. transmitting thoughts wirelessly from his brain to an electronic device on Cathy's arm. >> Does i ...

Here is Tula Berkeley. [applause] I never feel more alive than when I'm on stage performing. Whether it be acting, singing, or dancing, the connection with my cast and crew, the magic in the room when the audience comes alive, it's unlike anything in the world, and I'm addicted to it.Whether as a very young child with dog ears dancing to how Much is that doggy in the window or belting at the top of my lungs with my favorite meadows Mustangs and Rock of Ages, there is no show too small and no challenge too g ...

[applause] What if your thoughts were seeds. They say hearing is the last sense to go when someone's dying. Even when the body is unresponsive, the brain still listens and responds to sound.I've seen this happen so many times in my career being a nurse for 20 years. Even at the threshold of death, we are still taking in sound. On March 27th, 2021, my father told me he was going to take his last breath and he did.But then 15 minutes later, he came back, not with words, not with explanations, but with a heart ...

[applause] I remember waking up lying in a dense forest, looking up at the sky through the tops of the trees, but having no recollection of how I'd gotten there. Within seconds, my brain was overflooded with pain signals, and then everything went dark. I came back in fragments being dragged out of the woods, paramedics cutting my clothes off in the ambulance, and then waking up in the ICU, having difficulty speaking.At 15, I nearly died in an accident that left me overcoming a speech impediment following tr ...