Core Viewpoint - The article discusses the incident where a student with autism was denied admission to a vocational school, highlighting societal misconceptions about autism and the need for greater understanding and acceptance of individuals with disabilities [3][4][5]. Group 1: Incident Overview - A 19-year-old student, recommended by the Guangdong Provincial Disabled Persons' Federation, was admitted to Guangdong Mechanical Technician College but was rejected on the day of enrollment due to his autism diagnosis [3]. - The school claimed concerns about the student's impact on other students and his ability to cope with the academic environment, despite having accepted him months prior without objections [3][4]. Group 2: Societal Perception and Misunderstanding - The rejection reflects a broader societal misunderstanding of autism, where individuals with the condition are often viewed as "difficult" or "threatening," leading to discrimination [4][5]. - Experts indicate that autism does not inherently disrupt the learning environment and that inclusive education can benefit both autistic students and their peers [5]. Group 3: Call for Change - The article emphasizes the need for increased scientific literacy and awareness about autism to combat prejudice and promote acceptance [5][6]. - It advocates for a societal shift in attitudes towards individuals with disabilities, stressing that discrimination based on misunderstanding is unacceptable [6]. Group 4: Institutional Response - Following public backlash, the Guangdong Mechanical Technician College plans to reassess the situation by collaborating with the provincial disabled persons' federation and conducting a professional evaluation of the student [7]. - The school's commitment to addressing the issue and ensuring educational equity is seen as a positive step towards rectifying the situation [7].

Core Viewpoint - The incident involving the rejection of a student with autism by Guangdong Mechanical Technician College highlights societal biases and misunderstandings surrounding autism, emphasizing the need for greater awareness and acceptance of individuals with disabilities [1][2][4]. Group 1: Incident Overview - A 19-year-old student with autism was admitted to Guangdong Mechanical Technician College but was rejected on the day of enrollment due to concerns about his impact on other students [1]. - The college had previously accepted the student without objections, raising questions about the timing and reasoning behind the rejection [1][2]. - The college has a history of training disabled students, having collaborated with the Guangdong Provincial Disabled Persons' Federation since 2018 to educate over 100 disabled students [2]. Group 2: Societal Perception and Misunderstanding - The rejection reflects a deeper societal misunderstanding of autism, where individuals with the condition are often viewed as "difficult" or "dangerous," leading to pressure on institutions to exclude them [2][3]. - Experts indicate that autism does not inherently disrupt the learning environment and that inclusive education can benefit both autistic students and their peers [3]. - There is a call for increased scientific literacy and understanding of autism to combat societal biases and promote acceptance [3]. Group 3: Institutional Response and Future Actions - The college has committed to addressing the situation by ensuring educational fairness and considering professional assessments of the student's capabilities [4][5]. - The Guangdong Provincial Disabled Persons' Federation will collaborate with parents to evaluate the student's ability to participate in the program, aiming to uphold the student's right to education [4][5].

Core Viewpoint - The study identifies mitochondrial dysfunction as a potential mechanism for autism-related social deficits through the elevation of H₂S levels and subsequent sulfhydration of synaptic proteins [3][6]. Group 1: Research Findings - Mitochondrial dysfunction leads to increased H₂S levels, which mediates the sulfhydration of the synaptic protein mGluR5, potentially contributing to social deficits associated with autism [3][6]. - The research focused on the anterior cingulate cortex (ACC) and found that overexpression of cystathionine β-synthase (CBS) in wild-type mice impaired synaptic transmission and social function, while its knockdown effectively restored these functions in two autism mouse models [4][6]. - Significant changes in the sulfhydration of synaptic proteins were observed in Shank3b−/− ACC, confirming excessive sulfhydration of mGluR5 in both autism mouse models [4][6]. Group 2: Implications and Mechanisms - The study suggests that excessive H₂S and the sulfhydration of synaptic proteins may be underlying mechanisms for social function impairments in autism [6][7]. - Reducing the intake of sulfur-containing amino acids improved social dysfunction in Shank3b−/− and Fmr1−/y mice, as well as synaptic defects in corresponding human neurons [4][7].

Core Viewpoint - The article discusses the rising prevalence of autism and explores the underlying reasons for this increase, emphasizing that the rise is largely attributed to improved diagnostic practices rather than an actual increase in cases [3][6][16]. Summary by Sections Increase in Autism Diagnosis - The prevalence of autism has risen significantly, with the rate in the U.S. increasing from 1 in 150 children in 2000 to 1 in 31 children by 2022 [5][18]. - This trend is not limited to the U.S.; other high-income countries like the UK, Denmark, South Korea, and Japan have also reported similar increases [8]. Factors Contributing to Increased Diagnosis - Changes in diagnostic criteria over the years have led to more individuals being classified as autistic. For instance, the DSM and ICD have broadened their definitions, allowing for a wider range of symptoms and age groups to be included [12][14]. - A study indicated that approximately 60% of the increase in autism prevalence in Denmark from 1980 to 1991 could be attributed to changes in diagnostic standards [13]. - Increased awareness and reduced stigma around autism have led to more parents seeking diagnoses for their children, especially as educational support becomes more accessible [14][15]. Current Autism Prevalence Estimates - The U.S. Autism and Developmental Disabilities Monitoring Network reported that 1 in 31 children are diagnosed with autism, but some researchers question the accuracy of this data [18]. - A global estimate from 2021 suggested that the prevalence of autism spectrum disorder is approximately 1 in 127 individuals, totaling around 62 million people [18]. Genetic and Environmental Factors - Genetic factors are believed to play a significant role in autism, with a study estimating the heritability of autism at around 80% [22]. - Environmental factors are thought to have a smaller impact, with some studies linking advanced parental age and prenatal exposures to increased autism risk [23][24]. - Research indicates that there is no single environmental factor that significantly influences autism, and the interaction between genetic and environmental factors remains complex [25]. Research Initiatives and Funding - The NIH's Autism Data Science Initiative aims to explore the causes of autism and the effectiveness of existing interventions, focusing on the interaction between genetic and environmental factors [27]. - However, there are concerns about funding cuts to autism research, which have decreased from $274 million in early 2024 to $212 million in early 2025 [27].

在这场演讲中，艺术家杨放分享了与自闭症孩子相处的感人故事，探讨了艺术如何成为他们表达内心的“母语”，以及如何通过画笔发现他们隐藏的天赋与情感密码。 同时，她呼吁用爱与理解为每颗孤独的星星找到属于自己的轨道。 艺术家，EveryArt联合创始人。 This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx ...

Group 1 - The Brazilian Institute of Geography and Statistics (IBGE) reported that there are 14.4 million disabled individuals in Brazil, accounting for 7.3% of the population aged 2 and above [1][2] - Among disabled individuals, 8.3 million are women (8.1%) and 6.1 million are men (6.4%) [1] - The disability rate is significantly higher among the elderly, with over half of those aged 90 and above having at least one disability [1] Group 2 - The highest disability rate is found in the Northeast region at 8.6%, attributed to lower living quality and infrastructure [2] - Approximately 16% of households have at least one disabled member, rising to 19.3% in homes without toilets or sewage systems [2] - The prevalence of autism spectrum disorder (TEA) is reported at about 2.4 million individuals, or 1.2% of the national population, with the highest rates among children aged 5 to 9 at 2.6% [1][2]