北京贝尔生物工程股份有限公司（下称"贝尔生物"）的上市之路再次按下了"暂停键"，这家老牌体外诊 断企业曾在五年内多次转换赛道、冲击IPO，至今未果。 2025年9月29日，北京证券交易信息显示，贝尔生物的IPO审核状态变更为"中止"。这是这家成立于1995 年的老牌体外诊断企业自2020年以来第三次冲击资本市场，再次遇到波折。 多次闯关IPO 贝尔生物的IPO之路可谓一波三折。 2020年7月，贝尔生物首次申请在深交所创业板上市，但2021年2月就撤回了申请。经历短暂调整后，公 司在2021年10月转战上交所主板。 然而这一尝试同样并未如愿，直到2025年4月，贝尔生物改道北交所。6月30日，贝尔生物北交所IPO获 受理。但仅仅三个月后，公司的上市进程再度停止。 此次IPO中止的直接原因是"财务报告到期补充审计事项"。据北交所规则，公司需更新财务资料，而贝 尔生物主动选择了中止审核。 本报（chinatimes.net.cn）记者张斯文 于娜 北京报道 据招股书，贝尔生物计划将募集资金分别投入以下两个项目： 体外诊断试剂及仪器生产基地建设项目，拟投入募集资金4.42亿元，用于扩大现有产品的生产能力，建 设新的 ...

Core Viewpoint - The company reported a decline in revenue and net profit for the first half of 2025, with a focus on domestic market challenges and strong overseas growth opportunities [1][2][3][4]. Domestic Market Performance - The domestic market is under pressure due to policy impacts, but large-scale installations are ongoing, laying a foundation for long-term growth. In H1 2025, domestic revenue was 1.229 billion yuan, down 12.81% year-on-year, with reagent revenue decreasing by 18.96% and instrument revenue increasing by 18.18% [2]. - The company completed the installation of 774 units, with large machines accounting for 74.81% and coverage rates for tertiary hospitals at 47.6% and for top-tier hospitals at 63.5% [2]. Overseas Market Performance - The overseas market showed strong growth, with revenue reaching 0.952 billion yuan, up 19.57% year-on-year. The reagent business grew by 36.86% due to increased installation volumes, with 1,971 units sold, and high-end models making up 77.02% of sales [3]. Financial Performance and Profitability - The company increased its sales and R&D investments, leading to temporary pressure on profits due to a higher proportion of low-margin products. The overall gross margin decreased to 68.44%, down 4.17 percentage points, and the net profit margin fell to 35.29%, down 5.56 percentage points [4]. - The company expects revenue for 2025-2027 to be 4.888 billion, 5.625 billion, and 6.477 billion yuan, with year-on-year growth rates of 7.78%, 15.07%, and 15.16%, respectively. Net profits are projected to be 1.866 billion, 2.183 billion, and 2.571 billion yuan, with corresponding growth rates of 2.06%, 16.98%, and 17.79% [4].

Core Viewpoint - The company, Dirui Medical, is facing significant financial challenges, with a projected net loss of 22 million to 33 million yuan for the first half of 2025, marking its first half-year loss in 11 years since its listing, contrasting sharply with a profit of 165 million yuan in the same period last year [2][3] Financial Performance - The company reported a 11.63% decline in revenue and a 48.5% drop in net profit for the full year of 2024, with the fourth quarter showing a staggering 87.14% decrease in total revenue [4] - The net profit for 2024 was only 142 million yuan, with a significant cash flow reversal from a net cash inflow of 224 million yuan in the previous year to a net outflow of 295 million yuan, a decline of 231.29% [4] Asset Quality and Impairment - Dirui Medical attributed its losses to a decline in overall gross profit and a substantial increase in asset impairment losses, with a provision for asset impairment of 23.89 million yuan announced alongside the earnings forecast [3][4] Product Structure and Market Position - The company has a product structure imbalance, with reagent revenue accounting for only 48.51% and instrument revenue at 51.49%, contrasting with industry leaders where reagent revenue is significantly higher [5] - The decline in gross margins for both reagent and instrument products was noted, with reagent gross margin dropping from 75.42% to 70.06% and instrument gross margin from 33.99% to 24.26% [4][5] Competitive Landscape - Dirui Medical faces intense competition from both domestic players like Mindray and international giants such as Abbott and Sysmex, particularly in the blood cell analysis market [6] - The company’s BF series blood cell analyzers, while technically advanced, struggle with brand recognition and channel development, hindering market penetration [6] Strategic Response and Management Changes - The company has outlined measures to focus on increasing reagent sales and expanding into international markets, although these strategies will require time to yield results [7][8] - Recent management changes include the departure of four board members, with new candidates from the China Resources background proposed, raising questions about the new leadership's ability to navigate the company out of its current difficulties [9]

Investment Rating - The report gives a "Buy" rating for the company with a target price of 47.95 RMB per share, based on a 21x PE valuation for 2025 [4]. Core Insights - The company is a leading player in the domestic in vitro diagnostics industry, primarily focusing on immunodiagnostics. The implementation of centralized procurement is expected to accelerate the domestic production process and enhance market share through high-speed analyzers [2][32]. - The company is expanding its product offerings across multiple innovative business areas, including automated laboratory workflows, molecular diagnostics, and microbiological mass spectrometry, which are expected to drive future growth [2][3][58]. - The international market expansion is underway, with overseas sales projected to reach 286 million RMB in 2024, reflecting a year-on-year growth of 36.6% [3]. Summary by Sections Investment Logic - The centralized procurement led by Anhui Province is expected to boost the demand for the company's products, with successful bids in the first round of procurement [2]. - The high-throughput chemiluminescence immunoassay analyzer AutoLumo A6000 has a detection speed of 600 tests per hour, which will enhance the company's market share in high-end products [2][49]. Business Expansion - The company is actively developing automated laboratory workflows, molecular diagnostics, and microbiological mass spectrometry systems, which are anticipated to create new growth avenues [2][3][58]. - The Sikun2000 gene sequencer is expected to capture market share following the ban on foreign competitor sales in China [2][3]. Financial Forecast and Investment Advice - The projected net profits for 2025-2027 are 1.305 billion, 1.566 billion, and 1.884 billion RMB, respectively, with growth rates of 9%, 20%, and 20% [4]. - The company’s revenue is expected to grow from 4.471 billion RMB in 2024 to 7.081 billion RMB by 2027, with a compound annual growth rate of approximately 18.74% [8]. Market Trends - The domestic in vitro diagnostics market is expected to grow significantly, with the immunodiagnostics segment projected to reach 105.5 billion RMB by 2028, reflecting a compound annual growth rate of 19.1% [39][40]. - The company’s international sales have increased from 1.5% of total revenue in 2017 to an estimated 6.5% in 2024, indicating a growing focus on global markets [25][27]. Competitive Landscape - The company holds a market share of 4% in the domestic immunodiagnostics market, which is dominated by foreign brands, indicating significant potential for growth through domestic product enhancements and procurement policies [45][46].