Summary of the Medical Aesthetic Industry Conference Call Industry Overview - The medical aesthetic industry has shown a GMV (Gross Merchandise Volume) growth of 13% year-on-year, reaching 450 million yuan for the period from January to November 2025, although the growth rate has slowed compared to the pandemic period [1][2] - The revenue from the Double Eleven shopping festival accounts for approximately 5% of the total revenue in Q4 [4] Key Insights - **Customer Spending Trends**: - The average transaction value for medical aesthetic products has significantly decreased, with an overall decline of 4% year-on-year. Non-surgical procedures, such as laser treatments and injections, saw a decline of 8-9%, while surgical procedures experienced a stable growth of 2% [1][5] - The long-term trend indicates a continuous decrease in average transaction value, particularly for injection products, which have seen a decline of over 8% [5][6] - **Market Dynamics**: - The decrease in product prices is attributed to increased information transparency, stricter regulations leading to product homogenization, and a rise in new products from upstream manufacturers, which lowers procurement costs [6][7] - Younger consumers are increasingly favoring lower-priced options, and demand from second and third-tier cities has contributed to the decline in average transaction value [6][7] - **Consumer Demographics**: - The proportion of male consumers has increased but remains low at around 5%. The share of younger consumers (ages 18-22) has decreased, while the proportion of consumers aged 35 and above has increased, showing a preference for mid to high-end services and higher repurchase rates [7] - Combined treatments, such as using laser devices alongside injections, have become the norm, reflecting a trend towards package sales [7] Financial Performance - The company has experienced a slowdown in revenue growth, with top-tier institutions reporting a year-on-year revenue increase of about 6% and a net profit margin maintained between 8% and 10% [3][11] - Customer traffic has increased by 12% year-on-year, but the average transaction value has decreased by approximately 5% [11] - The overall revenue growth for the year is expected to be no more than 10%, indicating a shift towards stable growth in the industry [3][11] Competitive Landscape - The market for various medical aesthetic products has become increasingly competitive, with mid-sized and chain clinics experiencing a general slowdown in growth. The overall industry is still growing at over 5%, but the explosive growth phase has ended, leading to a focus on refined operations [13] - The collagen market has seen significant growth, particularly for new specifications introduced by companies to extend product life cycles, despite increased competition from new entrants [19] Inventory Management - Medical aesthetic institutions typically maintain an inventory cycle of about 10 to 15 days, with a slight increase in inventory towards the end of the year to meet peak business demands and supplier requirements [23][24] Conclusion - The medical aesthetic industry is undergoing significant changes, with shifts in consumer behavior, pricing pressures, and competitive dynamics. Companies are adapting their strategies to maintain profitability and market share in a more regulated and competitive environment.

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不 負 責，對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明，並 明 確 表 示，概 不 就 因 本 公 告 全部或任何部份內容而產生或因倚賴該等內容而引致之任何損失承擔任何責 任。 Sihuan Pharmaceutical Holdings Group Ltd. 四環醫藥控股集團有限公司 （於百慕達註冊成立的有限公司） （股份代號：0460） 自願公告 四環醫藥旗下渼顏空間自主研發的 含L－肌 肽 的 複 合 溶 液 水 光 針「凍 妍」 獲得國家藥監局批准上市 四 環 醫 藥 控 股 集 團 有 限 公 司（「本公司」或「四環醫藥」，連 同 其 附 屬 公 司，統 稱 為「本集團」）董 事 會（「董事會」）欣 然 宣 佈，本 集 團 旗 下 渼 顏 空 間 生 物 科 技（吉 林） 有 限 公 司（「渼顏空間」）自 主 研 發 的 注 射 用 透 明 質 酸 鈉 複合溶液（商 品 名：凍 妍， 「該產品」）正 式 獲 得 中 國 國 家 藥 品 監 督 管 理 局（「國家藥監局」）頒 發 第 三 類 醫 療 器 械 註 冊 ...

Core Viewpoint - The company, Langzi Co., Ltd. (002612), is accelerating its expansion in the fashion industry and medical beauty sector through both organic growth and acquisitions, with a recent announcement to acquire a controlling stake in Chongqing Milan Baiyu Cosmetic Surgery Hospital for nearly 100 million yuan [2][3]. Group 1: Acquisition Details - Langzi's subsidiary, Beijing Langzi Medical Management Co., plans to acquire 67.5% of Chongqing Milan Baiyu for 92.475 million yuan, based on an assessed value of 137 million yuan for the entire hospital [3][4]. - Chongqing Milan Baiyu is a specialized medical beauty hospital with a total operating area of 5,600 square meters, located in a prime area of Chongqing [3][4]. - The hospital has a comprehensive treatment capability and has obtained the necessary medical licenses to operate in the medical beauty sector [4]. Group 2: Financial Projections - The hospital's projected revenues for 2024 and Q1 2025 are 148 million yuan and 38 million yuan, with net profits of approximately 5.15 million yuan and 4.02 million yuan, respectively [4][5]. - Future revenue forecasts from 2025 to 2027 predict revenues of 111 million yuan, 157 million yuan, and 168 million yuan, with net profits of 5.09 million yuan, 9.73 million yuan, and 11.66 million yuan, respectively [5]. Group 3: Market Potential - The medical beauty industry in China is experiencing rapid growth, with a projected annual compound growth rate of 10%-15% from 2024 to 2027 [6]. - The current market penetration rate in China is only 4-5%, indicating a potential for 2-5 times growth compared to markets like the U.S. and South Korea [6]. - Langzi has established a diversified business ecosystem in the fashion industry, including 42 medical beauty institutions, and aims to expand its national footprint [6][7]. Group 4: Strategic Approach - Langzi employs a "cultivation and acquisition" model, initially investing in medical beauty funds to identify and nurture potential acquisition targets before making direct purchases [8][10]. - The company has participated in the establishment of multiple medical beauty funds to facilitate this strategy, ensuring that acquired institutions are well-managed and profitable before integration [8][10]. - Langzi has developed a comprehensive management system for medical beauty institutions, enhancing its ability to replicate successful operational models across its acquisitions [10].

Core Viewpoint - Aimeike (300896.SZ), a leading player in the medical aesthetics industry, reported a significant decline in revenue and net profit for the first half of 2025, leading to a drop in stock price following the announcement [1][2]. Financial Performance - The company achieved operating revenue of 1.299 billion yuan, a year-on-year decrease of 21.59% [1]. - Net profit attributable to shareholders was 789 million yuan, down 29.57% year-on-year [1]. - The net profit after deducting non-recurring gains and losses was 722 million yuan, a decline of 33.70% [1]. - The net cash flow from operating activities was 655 million yuan, down 43.06% year-on-year [1]. - Basic and diluted earnings per share were both 2.62 yuan, a decrease of 29.57% [1]. - The weighted average return on net assets was 10.10%, down 6.52 percentage points from the same period last year [1]. Product Performance - Revenue from solution-type injection products was 744 million yuan, a decrease of 23.79% year-on-year [1]. - Revenue from gel-type injection products was 493 million yuan, down 23.99% year-on-year [1]. - Gross margins for solution-type and gel-type products were 93.15% and 97.75%, respectively [1]. Research and Development - The company invested 157 million yuan in R&D, an increase of 24.47% year-on-year [1]. - Several products, including botulinum toxin injections and lidocaine cream, are in the registration phase, while others are undergoing clinical trials [1]. Asset and Equity Position - As of the end of the reporting period, total assets were 8.765 billion yuan, an increase of 5.09% from the previous year [2]. - Net assets attributable to shareholders were 7.456 billion yuan, a decrease of 4.37% from the previous year [2]. Dividend Distribution - The board approved a profit distribution plan to pay a cash dividend of 12 yuan (including tax) for every 10 shares, with no bonus shares or capital reserve transfers [4]. Legal Matters - The company is involved in arbitration with *ST Suwu regarding the "Tian Yan Needle" and has taken steps to protect its interests in the ongoing legal dispute [5].

Group 1 - The core viewpoint of the report highlights the growth potential of Ruiri Medical Technology, which is expanding its business from energy-based medical aesthetics to a diversified beauty and health ecosystem through acquisitions and market expansion [1] - The global market for energy-based medical devices reached $5.7 billion in 2022, with a projected CAGR of 13.8% from 2023 to 2030, indicating strong growth prospects [1] - North America accounted for 35.4% of the global market in 2022, while the Asia-Pacific region is expected to have a higher growth rate of 15.6% from 2023 to 2030 [1] Group 2 - The company is focusing on product development, channel expansion, and research and development to achieve steady global growth [1] - The product range includes various energy sources such as lasers, intense pulsed light, radiofrequency, ultrasound, plasma, and shockwave, catering to comprehensive beauty needs [1] - The company has established a sales network covering over 110 countries and regions by combining distribution and direct sales strategies, aiming for significant optimization of product pricing and overall performance [1] Group 3 - Long-acting botulinum toxin is expected to gain rapid market acceptance due to its advantages, including a median duration of 6 months and a maximum of 9 months, addressing consumer concerns about frequent injections [2] - The industry is anticipated to accelerate its development phase due to improved policies, consumer education, product technology iterations, and channel penetration [2] - Revenue projections for the company are $395 million, $468 million, and $530 million for 2025, 2026, and 2027, respectively, with corresponding net profits of $31 million, $45 million, and $57 million [2]

Core Insights - The medical beauty industry is rapidly emerging, driven by advancements in medical technology and evolving consumer perceptions, expanding from traditional cosmetic surgery to non-invasive beauty treatments, laser skincare, and body management [1][16] - The industry is experiencing significant growth potential due to improved consumer decision-making facilitated by big data, alongside a push towards standardization through enhanced regulation [1][16] - The long-term outlook for the industry remains positive, supported by rising disposable incomes and increasing demand for quality living [1][16] Industry Overview - Medical beauty, abbreviated as "医美," utilizes medical methods, including drugs, instruments, and surgeries, to enhance external beauty and improve physiological functions [2] - The industry encompasses various segments, including facial beauty, body beauty, skin beauty, non-invasive beauty, and oral beauty [2] Market Trends - Consumer acceptance of light medical beauty is increasing, with 34% of consumers planning to engage in light medical beauty services in the coming year, reflecting a 36% year-on-year growth [5] - The emerging consumer base includes young people, men, and consumers from lower-tier markets, indicating a shift in demand driven by changing aesthetic values and rational consumption attitudes [5] Industry Structure - The medical beauty industry chain consists of upstream products and equipment, midstream service providers, and downstream customer acquisition platforms, with a stable upstream structure and a competitive midstream landscape [7][8] - Upstream manufacturers face high entry barriers due to regulatory requirements and technical challenges, making it the most profitable segment of the industry [8] - The downstream market is characterized by intense competition and low concentration, with 71% of service providers being private clinics or beauty salons [10] Market Size and Growth - The Chinese medical beauty market has shown steady growth, with a compound annual growth rate (CAGR) of 17.5% from 2017 to 2021, reaching nearly 190 billion yuan, and is projected to grow at a CAGR of 15.2% to nearly 400 billion yuan by 2026 [11] - The penetration rate of medical beauty services in China was 4.5% in 2022, indicating significant room for growth compared to Japan (11.3%), the U.S. (17.2%), and South Korea (22.0%) [11] Regulatory Environment - The industry has faced challenges such as varying qualifications, false advertising, and price transparency issues, prompting the government to enhance regulatory frameworks and industry standards [14] - Increased compliance awareness among institutions and improved consumer protection mechanisms are expected to foster a healthier development phase for the industry [14] Investment Opportunities - Key companies in the medical beauty sector include Aimeike, Huaxi Biological, Longzi Co., and Huadong Pharmaceutical, which are positioned to benefit from the industry's growth and regulatory improvements [16]

Group 1 - The core viewpoint of the article highlights that New Oxygen Technology (SY.US) reported a revenue decline in Q1 2025, but still exceeded market expectations [1] - In Q1 2025, the company's revenue reached 40.97 million USD, a decrease of 6.6% year-on-year, while the GAAP diluted loss per share was 0.04 USD, slightly better than the market average expectation of a loss of 0.05 USD [1] - The decline in revenue was primarily due to a reduction in the number of medical beauty institutions on the subscription platform [1] Group 2 - The total transaction amount for medical beauty treatments facilitated by the platform in Q1 was 30.32 million RMB, down from 36.71 million RMB in the same period of 2024 [1] - The number of verified paid visits exceeded 45,500, showing a nearly ninefold increase compared to approximately 4,600 visits in the same period of 2024 [1] - The number of active users as of March 31, 2025, was over 75,700, compared to about 8,000 in the same period of 2024 [1] Group 3 - As of March 31, 2025, New Oxygen operates 23 medical beauty centers in nine major cities, with 18 centers achieving positive monthly operating cash flow [2] - For Q2 2025, the company expects medical beauty service revenue to be between 120 million RMB (approximately 16.5 million USD) and 140 million RMB (approximately 19.3 million USD), representing a year-on-year growth of 337.3% to 410.1% compared to the same period in 2024 [2]