Market Overview - The A-share market showed strong gains, with the Shanghai Composite Index recovering above 3900 points and the CSI 300 index surpassing 4600 points, while the CSI 500 opened over 7200 points [1] - The number of rising stocks significantly outnumbered declining ones, with trading volume showing a moderate increase [1] Sector Performance - Hainan local stocks experienced a surge, with the sector index rising over 9% and trading volume exceeding the previous day's total within the first hour [3] - Notable stocks such as Shen Nong Agricultural and Kangzhi Pharmaceutical hit the 20% daily limit, while Hainan Airlines and others also saw rapid gains [3] Hainan Tourism and Retail - On December 18, Hainan's duty-free shopping on the first day of closure reached 161 million yuan, with a year-on-year increase of 61% in sales [6] - The number of shoppers was 24,800, reflecting a 53.1% increase, and the number of items purchased rose by 25.5% [6] - Sanya's duty-free sales reached 118 million yuan, with a 60% increase in customer traffic [6] - Online travel booking platforms reported a significant rise in flight bookings to Hainan, with increases of 19% and 51% for flights to Haikou and Sanya, respectively [6] Semiconductor Industry - The photolithography machine sector is experiencing high demand, with related stocks rising over 3% and approaching historical highs [8] - ASML's advanced extreme ultraviolet (EUV) lithography technology has been successfully applied in biomedical research, opening new avenues for molecular sensing [10] - The World Semiconductor Trade Statistics (WSTS) predicts a 22.5% increase in global semiconductor revenue in 2025, reaching $772 billion, followed by a 26.3% increase in 2026 to $975 billion [11]

Core Viewpoint - The article discusses the successful demonstration of wafer-scale fabrication of solid-state nanopores using extreme ultraviolet (EUV) lithography technology by imec, marking a significant step towards low-cost mass production in the molecular sensing field [2][3]. Group 1: Technology and Innovation - imec has successfully created highly uniform nanopores with diameters as small as approximately 10nm on a 300mm wafer, combining EUV lithography with etching techniques to achieve nanoscale precision and repeatability [3]. - Solid-state nanopores, etched in silicon nitride membranes, allow for single-molecule detection by generating real-time analyzable electrical signals when immersed in liquid and connected to electrodes [2][3]. - The technology overcomes limitations faced by biological nanopores, such as stability and integration, making solid-state nanopores ideal for scalable, high-throughput sensing applications [2][3]. Group 2: Applications and Future Prospects - The advancements in EUV nanopore technology are expected to enable rapid diagnostics, personalized medicine, and molecular fingerprinting [4]. - imec is developing a modular readout system with scalable fluid control technology to provide a platform for chemical development related to these applications [4]. - A paper on a 256-channel event-driven readout for solid-state nanopore single-molecule sensing will be presented at the 2026 IEEE International Solid-State Circuits Conference (ISSCC), showcasing imec's concept validation ASIC readout [4].