Core Viewpoint - The article highlights the recognition of outstanding women in the fields of scientific instrument research, testing technology application, and laboratory construction during the International Women's Day celebration held by the All-China Women's Federation on March 2, 2025, showcasing their contributions to national strategies and technological advancement [2][3]. Group 1: National Flag Bearers - Zhu Beiwei, an academician of the Chinese Academy of Engineering, is recognized for her long-term dedication to food processing and safety detection technology research [5]. - Yan Ning, an academician of the Chinese Academy of Sciences, has made pioneering achievements in structural biology, promoting the development of life science instruments and experimental technologies [5]. Group 2: Notable Women in Scientific Instrumentation and Laboratory Construction - Zhang Jinlan, deputy director of the Drug Analysis Research Room at the Chinese Academy of Medical Sciences, focuses on drug analysis instrument research and application [7]. - Xu Yuan, director of the Strategic Research Center at Qiyuan National Laboratory, specializes in artificial intelligence and experimental platforms [7]. - Liu Bingbing, director of the High Pressure and Superhard Materials National Key Laboratory at Jilin University, is involved in high-pressure scientific instruments [7]. Group 3: Notable Women in Testing Technology Application - Yu Qinghua, group leader at the Shanghai Institute of Technical Physics, focuses on optical remote sensing instruments [9]. - Wang Yang, director at the Suzhou Aerospace Information Research Institute, specializes in aerospace detection instruments [9]. - Zhang Xin, deputy director of the Strong Magnetic Field Science Center at the Hefei Institute of Physical Science, is involved in strong magnetic field scientific devices [9]. Group 4: Notable Women in Various Testing Fields - Ma Wei, technical leader at the Harbin Customs Technical Center, is responsible for customs food testing [9]. - Wang Huizhi, a senior technician at the Huaihe City Public Security Bureau, specializes in forensic toxicology analysis [9]. - Zhang Jing, deputy director of the Zhuzhou Water Investment Group's drainage company, focuses on water quality testing [9]. Group 5: Notable Groups - The Green Solvent Properties and Applications Research Team from the Chinese Academy of Sciences focuses on green solvent analysis technology [11]. - The Agricultural Products Quality Testing Center in Heilongjiang specializes in agricultural product quality testing [12]. - The Environmental Monitoring Center in Hunan is involved in atmospheric environment monitoring [13]. These individuals and groups represent the excellence in scientific instrument research and testing, contributing significantly to technological innovation and high-quality development [12][13].

Core Viewpoint - The "3i Award - Special Contribution Award for R&D" aims to recognize outstanding individuals who have made significant contributions to the development and innovation of scientific instruments in China, with the nomination process open from January 1 to March 15, 2026 [1][2][3]. Group 1: Award Overview - The "3i Award - Special Contribution Award for R&D" has been held annually since 2013, celebrating individuals who have made notable contributions to scientific instrument development in China [3]. - The award encourages innovation and accelerates the development of the scientific instrument industry in China [3]. Group 2: Nomination Process - The nomination process includes self-nomination, public recommendation, and recommendations from previous award winners [2][4][5]. - Candidates can submit their applications via email or by downloading the nomination form [4][5][6]. Group 3: Previous Award Winners - Notable past winners include: - Xu Ying, who developed China's first X-ray three-dimensional microscope, achieving a spatial resolution of 500 nanometers and generating over 850 million yuan in output [10]. - Yang Peiqiang, who led the development of high-end scientific instruments, particularly in nuclear magnetic resonance imaging, achieving significant advancements in accuracy and speed [11]. - Duan Yixiang, who has contributed to the development of innovative spectrometry and mass spectrometry technologies, addressing critical safety monitoring issues in nuclear power [13]. - Zhang Shulian, recognized for his pioneering work in laser nanomeasurement technology [15]. Group 4: Evaluation Criteria - Candidates must meet specific criteria, including having research results primarily completed or transformed in China and at least one invention patent [31][32]. - Award winners should demonstrate significant contributions to addressing major application needs and breaking international monopolies in technology [32].

Core Viewpoint - The article discusses the announcement of the 2025 "Sensor and Scientific Instrument Innovation Research" project, specifically the "National Instrument Beijing Application" direction, which includes a public listing of 21 proposed projects for funding [1][2]. Summary by Relevant Sections - **Announcement Details** - The Beijing Municipal Science and Technology Commission and the Zhongguancun Science Park Management Committee have released a public notice regarding the proposed projects for the 2025 funding cycle [1][2]. - The public notice period is set from December 1 to December 5, 2025, during which stakeholders can submit objections via email [2]. - **Proposed Projects** - The public listing includes various innovative projects such as: - Cell Xpanse live cell wide-field all-time super-resolution microscope evaluation and application demonstration [4]. - KYKY-EM8200 scanning electron microscope evaluation and promotion research [4]. - Multi-functional atomic force microscope evaluation, application validation, and promotion [4]. - Development of a research platform integrating liquid chromatography, ion chromatography, surface plasmon resonance, and triple quadrupole mass spectrometry [4]. - Evaluation and promotion of domestic gas chromatography-mass spectrometry systems [4]. - Standardized evaluation and innovative application development of live imaging systems for multi-tissue pathology and organoids [4]. - **Participating Institutions** - Various prestigious institutions are involved in these projects, including: - Chinese Academy of Sciences [4]. - Tsinghua University [4]. - Peking University [4]. - Beijing University of Aeronautics and Astronautics [4]. - Beijing Institute of Technology [4].

Core Viewpoint - The development of a multi-color miniaturized two-photon microscope enables high-resolution imaging of deep brain structures in freely moving mice, significantly advancing brain science research and understanding of neurological diseases [2][3]. Group 1: Technological Advancements - The new microscope represents a significant technological breakthrough, allowing for multi-color imaging and the observation of various cell types simultaneously, overcoming previous limitations of single-color imaging [3][4]. - The fourth-generation system has achieved advancements in three dimensions: multi-color excitation, deep brain imaging, and multi-scale observation, enhancing the ability to study complex neural interactions [3][4]. - The ultra-broadband anti-resonant hollow-core fiber developed allows for low-loss, low-dispersion transmission of multi-wavelength femtosecond pulse lasers, which is crucial for observing multiple cellular functions [4]. Group 2: Research Implications - The microscope has been successfully used to visualize dynamic changes in brain cells and organelles in Alzheimer's disease model mice, providing critical insights into early cellular changes associated with the disease [4]. - The technology has been fully domesticated and has already been exported to multiple countries, indicating its potential for international application [4]. Group 3: Future Research Directions - Future research will focus on integrating optogenetics to create a "read-write" loop, enabling both the reading of neuronal electrical activity and the optical manipulation of specific neurons [5]. - There is a goal to increase imaging speed from 10-20 Hz to 1 kHz, allowing for real-time recording of brain electrical activity [5].

Core Viewpoint - The Shanghai Municipal Science and Technology Commission has approved 8 projects under the 2025 "Scientific Instruments" key technology R&D plan, aiming to enhance the independent R&D capabilities of high-end scientific instruments and support related industry development, with a total funding of 18 million RMB [1][2][3]. Project Overview - The approved projects cover various cutting-edge scientific instruments and technology fields, including: - Miniaturized polarization-independent superconducting single-photon detectors - High-resolution, high-throughput live-cell light-sheet imaging systems - High-end anti-gas-phase surface energy analyzers - Nuclear electrochemical water quality monitoring high-end scientific instruments - Fully automatic ultra-fast visualization of biological sample freeze-thaw instruments - High-end pure water and ultra-pure water systems for the electronics industry - Development of high-end flow cytometry fluorescent dyes - Development of high-end metabolic enzymes and their activity detection reagent kits [2][4]. Funding Details - The total funding allocated for this batch of projects is 18 million RMB, with 14.4 million RMB to be disbursed in the 2025 fiscal year. The notification emphasizes that project undertakers must effectively manage and implement the projects to ensure timely completion of research objectives [3][6].

Core Insights - Anhui Guoke Liangguang Technology Co., Ltd. has launched China's first tabletop extreme ultraviolet (EUV) absorption spectrometer, marking a significant breakthrough in high-end scientific instruments in China [1] - The product utilizes laser plasma technology to achieve a compact, high-brightness short-wavelength light source, which is expected to support the development of strategic new industries such as new materials and new energy [1] - The instrument integrates high-precision EUV detection technology into industrial production lines, providing a domestically controllable solution for core detection challenges in advanced manufacturing [1] Company Overview - Guoke Liangguang focuses on the research and development of high-brightness miniaturized light sources and related scientific instruments across the ultraviolet to X-ray spectrum [1] - The product range includes absorption spectroscopy, photoelectron spectroscopy, short-wavelength imaging equipment, and in-situ detection equipment for industrial production lines [1] Industry Context - The launch is seen as a practical implementation of local efforts to promote efficient transformation of scientific achievements and aligns with the national strategy for high-level technological self-reliance [2] - The event was guided by the Hefei Municipal Science and Technology Bureau and highlights the significant results of local innovation ecosystems [2]

Core Viewpoint - Guangdong Meisi Scientific Instrument Innovation Research Institute has successfully developed and delivered a customized gas chromatography-high-resolution time-of-flight mass spectrometry (GC-HRTOFMS) system, which features high resolution and switchable ion sources, suitable for complex sample analysis [1][2]. Group 1 - The GC-HRTOFMS system was commissioned by a university and has passed all technical tests upon delivery, now officially in use [2]. - The instrument integrates separation and high-precision detection, with a mass resolution exceeding 5000 [2]. - The switchable ion source design (photoionization source and EI source) significantly enhances the coverage and qualitative capabilities of compounds, allowing for accurate analysis of complex samples [2]. Group 2 - The system is applicable in various research fields, including chemistry and environmental studies, due to its ability to efficiently separate components in complex samples and accurately determine molecular weights and structural analysis [2].

Core Viewpoint - The article highlights the awarding of the "2024 Annual Special Contribution Award for R&D in the Scientific Instrument Industry" to Xu Ying, Chairman of Tianjin Sanying Precision Instrument Co., Ltd., recognizing his significant contributions to the development of high-end scientific instruments in China [1][2]. Group 1: Award Overview - The "China Scientific Instrument Industry R&D Special Contribution Award" was established in 2013 to honor individuals who have made outstanding contributions to scientific instrument technology innovation and industrialization [2][38]. - The award is presented annually at the China Scientific Instrument Development Annual Conference, with a maximum of two recipients each year [2][38]. - The 2025 edition marks the 12th year of the award, with Xu Ying being the 13th recipient [2]. Group 2: Xu Ying's Contributions - Xu Ying, who obtained his PhD from the University of Warwick in 1995, has over 20 years of experience in non-destructive testing and has developed a global perspective through his work in renowned international companies [6]. - He returned to China in 2009 with a mission to contribute to national scientific advancements, leading significant projects such as the development of China's first X-ray three-dimensional microscope with a spatial resolution of 500 nanometers, breaking foreign monopolies [6]. - Under his leadership, Tianjin Sanying Precision Instrument Co., Ltd. has transformed scientific research achievements into internationally advanced products, generating over 850 million yuan in output value and holding 10 invention patents [6]. Group 3: Historical Context of Award Recipients - The article provides a brief overview of past award winners, highlighting their contributions to various fields within scientific instrumentation, such as microwave chemistry, atomic spectroscopy, and the development of advanced analytical instruments [8][10][11][15][18][21][30][33][36]. - Each recipient has played a pivotal role in advancing China's capabilities in scientific instrumentation, often overcoming significant technological challenges and contributing to the country's self-sufficiency in high-tech fields [8][10][11][15][18][21][30][33][36]. Group 4: About the 3i Award - The "3i Award" (Innovative, Interactive, Integrative) was established in 2006 to recognize outstanding contributions in the scientific instrument and testing industry, with a focus on innovation and industry development [39][46]. - The award is based on principles of fairness and transparency, relying on evaluations from industry experts and a large user base to select awardees [39].